- ►diabetesjournals.org M Flodström, D Tsai, C Fine, A Maday, N Sarvetnick - Diabetes, 2003 - Am Diabetes Assoc Pancreatic β-cell antiviral defense plays a critical role in protection from coxsackievirus B4
(CVB4)-induced diabetes. In the present study, we tested the hypothesis that interferon
(IFN)-induced antiviral defense determines β-cell survival after infection by the human ... Cited by 23 - Related articles - BL Direct - All 4 versions
F Nicoletti, G Scalia, M Lunetta, F Condorelli, M Di … - Clinical Immunology and …, 1990 - Elsevier To investigate whether cytomegalovirus (CMV) infection may be related to islet cell antibodies
(ICA) production and/or to insulin-dependent diabetes mellitus (IDDM) development, we have
analyzed the prevalence of anti-CMV, IgM, and IgG antibodies and of ICA in 80 healthy ... Cited by 24 - Related articles - All 2 versions
JAN ROZING - Clinical & Developmental Immunology, 2003 - downloads.hindawi.com Most autoimmune diseases (AID) have been shown to have a strong genetic component.
However, studies on monozygous twins showed, that only in 50% of the cases both siblings developed
an AID of the same type (McFarland, 1992; Kumar et al., 1993). These data indicate that ... Cited by 7 - Related articles - View as HTML - BL Direct - All 12 versions
S Skarsvik, J Puranen, J Honkanen, M Roivainen, J … - Diabetes, 2006 - Am Diabetes Assoc Enteroviruses, particularly Coxsackie virus B4 (CVB4), are considered to be involved in the pathogenesis
of type 1 diabetes. We wanted to compare the characteristics of T-cell immune response to CVB4
in children with type 1 diabetes and healthy children with and without HLA risk-associated ... Cited by 10 - Related articles - BL Direct - All 6 versions
- ►nih.gov BS Coulson, PD Witterick, Y Tan, MJ Hewish, JN … - The Journal of …, 2002 - jvi.highwire.org Rotaviruses are the major cause of human infantile gastroenteritis worldwide, with multiple serotypes
causing regular winter outbreaks until herd immunity is almost complete by 5 years of age
(4). These nonenveloped, triple-layered, double-stranded RNA viruses are members of ... Cited by 22 - Related articles - BL Direct - All 8 versions
- ►jimmunol.org MMW Chong, Y Chen, R Darwiche, NL … - The Journal of …, 2004 - Am Assoc Immnol In type 1 diabetes, cytokine action on cells potentially contributes to cell destruction by direct
cytotoxicity, inducing Fas expression, and up-regulating class I MHC and chemokine expression
to increase immune recognition. To simultaneously block cell responsiveness to multiple ... Cited by 37 - Related articles - BL Direct - All 4 versions
TM Szopa, DM Dronfield, T Ward, KW Taylor - Diabet Med, 1989 - interscience.wiley.com The long-term effects of Coxsackie B4 (CB4) infection of mice on pancreatic islet function were
investigated. Mice were inoculated with various strains of CB4 virus and 2, 3 and 6 months later
islet insulin synthesis and release from isolated islets were measured. Insulin release at ... Cited by 14 - Related articles - All 3 versions
[CITATION] Etiopatogenia do diabetes mellitus tipo 1. Aspectos genéticos e fatores ambientais
M Roivainen, P Ylipaasto, C Savolainen, J Galama, T … - Diabetologia, 2002 - Springer Aims/hypothesis. Direct infection of beta cells could explain the diabetogenic effect of
enteroviruses. Pri- mary adult human beta cells are susceptible to cox- sackievirus
infections, which could result in impaired beta-cell function or cell death ... Cited by 44 - Related articles - BL Direct - All 5 versions