- ►diabetesjournals.org M Hayashi, M Otsuka, R Morimoto, A … - Diabetes, 2003 - Am Diabetes Assoc Islets of Langerhans contain γ-aminobutyrate (GABA) and may use it as an
intercellular transmitter. In β-cells, GABA is stored in synaptic-like
microvesicles and secreted through Ca 2+ -dependent exocytosis. Vesicular ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org SD Chessler, WT Simonson, IR Sweet, LP … - Diabetes, 2002 - Am Diabetes Assoc Expression of GAD is a characteristic of the islets of Langerhans. GAD is
produced in a number of different tissues but is most abundant in brain and
pancreatic islets (1). There are two major isoforms of the enzyme: GAD65 ... Cited by 16 - Related articles - BL Direct - All 5 versions
A Muroyama, S Uehara, S Yatsushiro, N … - Diabetes, 2004 - Am Diabetes Assoc Many metabolic factors affect the secretion of insulin from β-cells and
glucagon from α-cells of the islets of Langerhans to regulate blood glucose.
Somatostatin from δ-cells, considered a local inhibitor of islet function, ... Cited by 9 - Related articles - BL Direct - All 7 versions
S Uehara, A Muroyama, N Echigo, R Morimoto … - Diabetes, 2004 - Am Diabetes Assoc In islets of Langerhans, l-glutamate is stored in glucagon-containing secretory
granules of α-cells and cosecreted with glucagon under low-glucose conditions.
The l-glutamate triggers secretion of γ-aminobutyric acid (GABA) from ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►aspetjournals.org M Storto, L Capobianco, G Battaglia, G … - Molecular pharmacology, 2006 - ASPET Recent evidence suggests that metabotropic glutamate (mGlu) receptors are
involved in the regulation of hormone secretion in the endocrine pancreas. We
report here that endogenous activation of mGlu5 receptors is required for ... Cited by 11 - Related articles - BL Direct - All 6 versions
[CITATION] Glutamatergic signaling in islet of Langerhans: thread entangled
N Echigo, Y Moriyama - Neuroscience letters, 2004 - Elsevier GABA acts as an inhibitory amino acid in the central nervous system and
peripheral tissues [1]. To use GABA as an intercellular transmitter, the central
nervous system and peripheral tissues develop the GABAergic system, which ... Cited by 4 - Related articles - All 3 versions
- ►jbc.org M Hayashi, H Yamada, S Uehara, R Morimoto … - Journal of Biological Chemistry, 2003 - ASBMB L-Glutamate is believed to function as an intercellular transmitter in the
islets of Langerhans. However, critical issues, ie where, when and how
L-glutamate appears, and what happens upon stimulation of glutamate ... Cited by 57 - Related articles - BL Direct - All 4 versions
JW Hell, R Jahn - Methods in enzymology, 1998 - ncbi.nlm.nih.gov 1: Methods Enzymol. 1998;296:116-24. Bioenergetic characterization of gamma-
aminobutyric acid transporter of synaptic vesicles. Hell JW, Jahn R. ... Cited by 6 - Related articles - BL Direct - All 2 versions
Y Akagi, A Hashigasako, P Degenaar, S … - Journal of Biochemistry, 2003 - Jpn Biochemical Soc This paper describes a method for imaging the endogenous release of glutamate
from cerebral neurons. This method is based on the reactions of glutamate
oxidase and peroxidase, and on the detection of hydrogen peroxide by a ... Cited by 7 - Related articles - BL Direct - All 5 versions
