- ►diabetesjournals.org SB Wheatcroft, MT Kearney, AM Shah, DJ … - Diabetes, 2003 - Am Diabetes Assoc IGFs and their binding proteins (IGFBPs) play a significant role in metabolic
regulation, and there is growing evidence that they also exert important
vascular effects. IGFBP-1 contributes to glucose counterregulation, and ... Cited by 20 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org SB Wheatcroft, AM Shah, JM Li, E Duncan, … - Diabetes, 2004 - Am Diabetes Assoc Type 2 diabetes is preceded by years of insulin resistance and is characterized
by reduced bioavailability of the antiatherosclerotic signaling molecule nitric
oxide (NO) and premature atherosclerosis. The relationship between ... Cited by 20 - Related articles - BL Direct - All 5 versions
- ►shouxi.net BT Noronha, JM Li, SB Wheatcroft, AM Shah, … - Diabetes, 2005 - Am Diabetes Assoc Previous studies have suggested an involvement of inducible nitric oxide
synthase (iNOS) in obesity, but the relation, if any, between this and
mechanisms underlying endothelial dysfunction in obesity is unknown. We ... Cited by 31 - Related articles - All 5 versions
MT Kearney, AJ Cowley, TA Stubbs, IA … - Clinical science (London, England: 1979), 1996 - ncbi.nlm.nih.gov 1. While the haemodynamic adjustments occurring after meal ingestion and the
different effects of meals of different composition on these changes are well
established, the mechanisms underlying these changes are less clear. ... Cited by 11 - Related articles - BL Direct - All 11 versions
SB Wheatcroft, MT Kearney - Trends in Endocrinology & Metabolism, 2009 - Elsevier Insulin-like growth factor (IGF)-binding proteins (IGFBPs) confer temporospatial
regulation to IGF bioactivity. Both stimulatory and inhibitory effects of IGFBPs
on IGF actions have been described, and IGF-independent effects of several ... Cited by 1 - Related articles - All 2 versions
PA Crossey, JS Jones, JP Miell - Diabetes, 2000 - Am Diabetes Assoc The insulin/IGF binding protein-1 (IGFBP-1) axis is important in coordinating
insulin- and IGF-mediated regulation of glucose metabolism and glycemia. Dys-
regulation of the axis may play a role in the patho- physiology of ... Cited by 46 - Related articles - BL Direct - All 3 versions
- ►physiology.org ER Duncan, SJ Walker, VA Ezzat, SB … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc Insulin resistance is well established as an independent risk factor for the
development of type 2 diabetes and cardiovascular atherosclerosis. Most studies
have examined atherogenesis in models of severe insulin resistance or ... Cited by 13 - Related articles - BL Direct - All 3 versions
E Monastyrskaya, N Folarin, I Malyshev, C … - Nitric Oxide, 2002 - Elsevier Multiple data indicates that nitric oxide (NO) donors retain immediate
protective effects against different disturbances in cardiovascular system. The
aim of the present study was to investigate delayed effects of nitric oxide ... Cited by 16 - Related articles - All 3 versions
- ►diabetesjournals.org AH Heald, KW Siddals, W Fraser, W Taylor, K … - Diabetes, 2002 - Am Diabetes Assoc The IGF system is increasingly implicated in the development of cardiovascular
disease. The effects of circulating IGFs on the vasculature are largely
modulated by IGFBPs, which control their access to cell-surface IGF ... Cited by 41 - Related articles - BL Direct - All 4 versions
VA Ezzat, ER Duncan, SB Wheatcroft, MT … - Diabetes, obesity & metabolism, 2008 - pt.wkhealth.com Patients with insulin resistance and type 2 diabetes have an excessive risk of
cardiovascular disease (CVD); this increased risk is not fully explained by
traditional risk factors such as hypertension and dyslipidaemias. There is ... Cited by 19 - Related articles - BL Direct - All 5 versions
