R Babaei-Jadidi, N Karachalias, N Ahmed, S … - Diabetes, 2003 - Am Diabetes Assoc Accumulation of triosephosphates arising from high cytosolic glucose
concentrations in hyperglycemia is the trigger for biochemical dysfunction
leading to the development of diabetic nephropathy—a common complication ... Cited by 169 - Related articles - BL Direct - All 5 versions
HP Hammes, X Du, D Edelstein, T Taguchi, T … - Nature Medicine, 2003 - med.uio.no Diabetes-specific microvascular disease is a leading cause of blindness, renal
failure and nerve damage. Diabetes-accelerated atherosclerosis leads to
increased risk of myocardial infarction, stroke and limb amputation. Large ... Cited by 331 - Related articles - BL Direct - All 9 versions
H Stracke, HP Hammes, D Werkmann, K Mavrakis … - Experimental and Clinical Endocrinology & Diabetes, 2001 - thieme-connect.com In rats with streptozotocin (STZ) induced diabetes the effect of (watersoluble)
thiamine nitrate and of (lipidsoluble) benfotiamine on peripheral nerve function
(motor nerve conduction velocity) as well as on the formation of advanced ... Cited by 63 - Related articles - All 5 versions
R Babaei-Jadidi, N Karachalias, C Kupich, N … - Diabetologia, 2004 - Springer Aims/hypothesis. Cardiovascular disease in diabetes is linked to increased risk
of atherosclerosis, increased levels of triglyceride-rich lipoproteins and
enhanced hepatic lipogenesis. The hepatic hexosamine pathway has been ... Cited by 33 - Related articles - All 5 versions
E Haupt, H Ledermann, W Köpcke - International journal of clinical pharmacology and …, 2005 - ncbi.nlm.nih.gov OBJECTIVE: The aim of the study was to evaluate the efficacy of benfotiamine
administered over three weeks (allithiamine; a lipid-soluble vitamin B1 prodrug
with high bioavailability) to patients with diabetic polyneuropathy in a ... Cited by 47 - Related articles - All 2 versions
TP Degenhardt, NL Alderson, DD Arrington, … - Kidney international, 2002 - chem.sc.edu Department of Chemistry and Biochemistry, Animal Resource Facility, and School
of Medicine, University of South Carolina, Columbia, South Carolina, and
Department of Laboratory Medicine, University of Minnesota School of ... Cited by 193 - Related articles - BL Direct - All 6 versions
- ►fasebj.org [PDF] JM Forbes, V Thallas, MC Thomas, HW … - The FASEB Journal, 2003 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.02-1102fje. Published online
July 18, 2003. The breakdown of pre-existing advanced glycation end ... Cited by 127 - Related articles - BL Direct - All 5 versions
G Winkler, B Pal, E Nagybeganyi, I Ory, M … - Arzneimittelforschung, 1999 - grande.nal.usda.gov Record Detail. Return to previous page, Save: Title: Effectiveness of different
benfotiamine dosage regimens in the treatment of painful diabetic neuropathy. ... Cited by 33 - Related articles - Cached - BL Direct - All 4 versions
- ►shouxi.net E Berrone, E Beltramo, C Solimine, AU Ape, M … - Journal of Biological Chemistry, 2006 - ASBMB Hyperglycemia is a causal factor in the development of the vascular
complications of diabetes. One of the biochemical mechanisms activated by excess
glucose is the polyol pathway, the key enzyme of which, aldose reductase, ... Cited by 37 - Related articles - BL Direct - All 7 versions
E Beltramo, E Berrone, S Buttiglieri, M Porta - Diabetes/Metabolism Reviews - interscience.wiley.com High glucose induces pathological alterations in small and large vessels,
possibly through increased formation of AGE, activation of aldose reductase and
protein kinase C, and increased flux through the hexosamine pathway. We ... Cited by 33 - Related articles - BL Direct - All 3 versions