F Maingrette, G Renier - Diabetes, 2003 - Am Diabetes Assoc Recent data suggest that plasma leptin may represent a cardiovascular risk factor in diabetic
patients. To gain further insight into the role of leptin in atherogenesis associated with
diabetes, we investigated in the present study the role of this hormone in the regulation of ... Cited by 61 - Related articles - BL Direct - All 4 versions
J Bełtowski, G Wójcicka, A Jamroz - Atherosclerosis, 2003 - Elsevier Obesity is an important risk factor of atherosclerosis; however, the mechanism of proatherogenic
effect of obesity is not definitely established. Recent studies suggest an important role of leptin
in obesity associated complications. We investigated the effect of chronic hyperleptinemia ... Cited by 78 - Related articles - All 11 versions
A Jalali, DA Morgan, WI Sivitz, MLG Correia, AL Mark, … - 2001 - nature.com Leptin is a protein produced by adipocytes. Leptin is known to markedly and rapidly increase
sympathetic nerve activity to the kidney and hindlimb of experimental animals. Recent studies
suggest that leptin may stimulate endothelial production of nitric oxide, which could ... Cited by 23 - Related articles - All 4 versions
- ►ahajournals.org K Stephenson, J Tunstead, A Tsai, R Gordon, … - … , and vascular biology, 2003 - Am Heart Assoc Methods and Results— Femoral artery endoluminal wire injury was performed in diabetic insulin
2 Akita (ins2 Akita ) and leptin receptor db/db (lepr db/db ) mutant mice. Neointima size in ins2
Akita mouse arteries was unchanged compared with nondiabetic wild-type littermates. ... Cited by 66 - Related articles - BL Direct - All 9 versions
I Maruyama, M Nakata, K Yamaji - Annals of the New York Academy of …, 2000 - ncbi.nlm.nih.gov We demonstrated that leptin showed effects on both platelets and endothelial cells through its
functional receptor. These effects are the vector to inducing thrombotic tendency. Leptin concentrations
used in our experiments correspond to that of leptin in the circulation of obese individuals. ... Cited by 41 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org LO'Rourke, SJ Yeaman, PR Shepherd - Diabetes, 2001 - Am Diabetes Assoc Leptin is produced in adipose tissue and acts in the hypothalamus to regulate food intake.
However, recent evidence also indicates a potential for direct roles for leptin in peripheral
tissues, including those of the immune system. In this study, we provide direct evidence ... Cited by 63 - Related articles - BL Direct - All 4 versions
T Kazumi, A Kawaguchi, T Hirano, G Yoshino - Metabolism, 2003 - Elsevier To determine which anthropometric, biochemical, and cardiovascular variables are associated
with serum levels of C-reactive protein (CRP) in young, apparently healthy men, a cross-sectional
study of 179 male college students aged 18 to 22 years was performed. Multiple ... Cited by 60 - Related articles - All 9 versions
- ►ahajournals.org JL Mitchell, DA Morgan, MLG Correia, AL Mark, WI … - Hypertension, 2001 - Am Heart Assoc Abstract—— Leptin decreases appetite and increases sympathetic nerve activity and arterial
pressure. Recent reports suggest that leptin may also have peripheral vasodilator actions that
would tend to reduce arterial pressure. We tested the hypothesis that the direct vascular ... Cited by 43 - Related articles - BL Direct - All 6 versions
A Oda, T Taniguchi, M Yokoyama - Kobe Journal of Medical Sciences, 2001 - med.kobe-u.ac.jp Leptin, a peptide secreted from adipose tissue, plays an important role in the regulation of food
intake and energy expenditure. In obese patients, plasma leptin levels are elevated and obesity
is one of the major risk factors for cardiovascular diseases. Therefore, in this study, we ... Cited by 176 - Related articles - View as HTML - BL Direct - All 3 versions
J Bełtowski, G Wójcicka, A Marciniak, A Jamroz - Life Sciences, 2004 - Elsevier Chronic hyperleptinemia induces arterial hypertension in experimental animals and may contribute
to the development of hypertension in obese humans; however, the mechanism of hypertensive
effect of leptin is not completely elucidated. We investigated the effect of leptin on whole- ... Cited by 48 - Related articles - All 4 versions
