- ►diabetesjournals.org TJ Huang, SA Price, L Chilton, NA Calcutt, DR … - Diabetes, 2003 - Am Diabetes Assoc Mitochondrial dysfunction has been proposed as a mediator of neurodegeneration in diabetes
complications. The aim of this study was to determine whether deficits in insulin-dependent neurotrophic
support contributed to depolarization of the mitochondrial membrane in sensory neurons ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org V Brussee, FA Cunningham, DW Zochodne - Diabetes, 2004 - Am Diabetes Assoc Diabetic polyneuropathy is the most common acquired diffuse disorder of the peripheral nervous
system. It is generally assumed that insulin benefits human and experimental diabetic neuropathy
indirectly by lowering glucose levels. Insulin also provides potent direct support of ... Cited by 66 - Related articles - BL Direct - All 5 versions
K Sugimoto, Y Murakawa, AAF … - Journal of the Peripheral …, 2002 - interscience.wiley.com Abstract The expression and localization of the insulin receptor (IR) was examined in rat dorsal
root ganglia (DRG) and spinal cord using Western blotting, in situ hybridization and
immunocytochemistry. Western blotting showed that the molecular weight of the IR β ... Cited by 47 - Related articles - BL Direct - All 3 versions
A Singhal, C Cheng, H Sun, DW Zochodne - Brain research, 1997 - Elsevier BRAIN RESEARCH ELSEVIER Brain Research 763 (1997) 209-214 Research report Near nerve
local insulin prevents conduction slowing in experimental diabetes Ash Singhal, Chu
Cheng, Hong Sun, Douglas W. Zochodne * Department of Clinical Neurosciences and ... Cited by 43 - Related articles - All 4 versions
NM Sayers, LJ Beswick, A Middlemas, NA Calcutt, AP … - Diabetes, 2003 - Am Diabetes Assoc The relation between neurofilament expression and/or phosphorylation in the proximal versus
distal components of the sensory peripheral neuraxis was studied and related to disorders in
structure and function of the distal axon of streptozocin (STZ)-induced diabetic rats ... Cited by 30 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org M Kishi, J Tanabe, JD Schmelzer, PA Low - Diabetes, 2002 - Am Diabetes Assoc Chronic hyperglycemia results in a predominantly sensory neuropathy. Recent studies suggest
that dorsal root ganglion (DRG) neurons comprise a specific target and may be responsible for
the important complication of diabetic sensory neuropathy, since hyperglycemia for ... Cited by 39 - Related articles - BL Direct - All 4 versions
P Fernyhough, TJ Huang, A … - Journal of the Peripheral …, 2003 - interscience.wiley.com Abstract Symmetrical sensory polyneuropathy, the most common form of diabetic neuropathy
in humans, is associated with a spectrum of structural changes in peripheral nerve that includes
axonal degeneration, paranodal demyelination, and loss of myelinated fibers – the latter ... Cited by 23 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org DW Zochodne, VMK Verge, C Cheng, H Sun, J … - Brain, 2001 - Oxford Univ Press Targeting of dorsal root ganglia by diabetes could account for the selective sensory abnormalities
that patients with early diabetic polyneuropathy develop. In this work, we addressed survival,
phenotype and gene expression in sensory neurones in lumbar dorsal root ganglia in a ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org C Cheng, DW Zochodne - Diabetes, 2003 - Am Diabetes Assoc Long-term experimental diabetes may best model the prominent and irreversible sensory deficits
of chronic human diabetic polyneuropathy. Whereas irretrievable loss of sensory neurons, if
present, would be an unfortunate feature of the disease, systematic unbiased counting ... Cited by 79 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] S Srinivasan, M Stevens, JW Wiley - Diabetes, 2000 - Am Diabetes Assoc We hypothesized that diabetic sensory neuropathy is associated with activation of apoptosis
and concomitant mitochondrial dysfunction. Studies were performed in excised intact and acutely
dissociated dorsal root gan- glion (DRG) neurons from control and streptozotocin- ... Cited by 119 - Related articles - BL Direct - All 5 versions
