- ►diabetesjournals.org S Wang, X Wu, TM Lincoln, JE Murphy-Ullrich - Diabetes, 2003 - Am Diabetes Assoc Hyperglycemia is a crucial factor in the development of diabetic nephropathy. We
previously showed that high glucose upregulates thrombospondin 1
(TSP1)-dependent transforming growth factor (TGF)-ß activation by altering ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►jbc.org S Wang, S Shiva, MH Poczatek, V Darley- … - Journal of Biological Chemistry, 2002 - ASBMB Excessive transforming growth factor- (TGF- ) activity in hyperglycemia
contributes to the development of diabetic nephropathy. Glucose stimulation of
TGF- activity and matrix synthesis are dependent on autocrine ... Cited by 42 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org M Saura, C Zaragoza, B Herranz, M Griera, L … - Circulation research, 2005 - Am Heart Assoc Many forms of vascular disease are characterized by increased transforming
growth factor (TGF)-ß 1 expression and endothelial dysfunction. Smad proteins
are a key step in TGF-ß–initiated signal transduction. We hypothesized ... Cited by 32 - Related articles - All 8 versions
- ►ahajournals.org NB Dey, NJ Boerth, JE Murphy-Ullrich, PL … - Circulation research, 1998 - Am Heart Assoc Abstract—Vascular lesions resulting from injury are characterized by a
thickening of the intima brought about in part through the production of
increased amounts of extracellular matrix proteins by the vascular smooth ... Cited by 45 - Related articles - BL Direct - All 7 versions
- ►jbc.org S Wang, J Skorczewski, X Feng, L Mei, JE … - Journal of Biological Chemistry, 2004 - ASBMB Thrombospondin 1 (TSP1) transcription is stimulated by glucose, resulting in
increased TGF- activation and matrix protein synthesis. We previously showed
that inducible expression of the catalytic domain of cGMP-dependent protein ... Cited by 34 - Related articles - BL Direct - All 4 versions
S Wang, J Skorczewski, X Feng, L Mei, JE … - Journal of Biological Chemistry, 2004 - ASBMB Page 1. 1 Glucose upregulates Thrombospondin 1 Gene Transcription and TGF-β Activity
through Antagonism of PKG repression via Upstream Stimulatory Factor 2 ... Related articles - All 2 versions
B He, GF Weber - European Journal of Biochemistry - interscience.wiley.com The transcription factor NF-κB is activated in cellular stress responses. This
requires rapid regulation of its function, which is accomplished, in part, by
various modes of phosphorylation. Even though diverse DNA binding subunits ... Cited by 26 - Related articles - BL Direct - All 8 versions
DIR Holmes, NA Wahab, RM Mason - Biochemical and Biophysical Research …, 1997 - Elsevier Diabetic nephropathy is characterised by an accumulation of extracellular matrix
proteins in the glomerular mesangium. Hyperglycaemia is a major factor promoting
this progressive expansion of the mesangial matrix. We have used the ... Cited by 29 - Related articles - BL Direct - All 5 versions
R Pawliczak, MJ Cowan, X Huang, UB … - Journal of Biological Chemistry, 2001 - ASBMB The effect of nitric oxide on p11 expression was studied in an immortalized
human bronchial epithelial cell line (BEAS-2B cells). Three nitric oxide donors
were used: spermine NONOate (SP), (±)-S-nitroso-N-acetylpenicillamine ... Cited by 16 - Related articles - BL Direct - All 5 versions
[CITATION] Platelet inhibition limits TGF-beta overexpression and matrix expansion following induction …