DA Sandoval, L Ping, AR Neill, S Morrey, SN Davis - Diabetes, 2003 - Am Diabetes Assoc Physiological levels of cortisol have been found to blunt neuroendocrine and metabolic responses
to subsequent hypoglycemia in humans. The aim of this study was to determine whether cortisol
acts directly on the brain to elicit this effect. A total of 41 conscious unrestrained Sprague- ... Cited by 20 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org DE Flanagan, T Keshavarz, ML Evans, S Flanagan, X … - Diabetes, 2003 - Am Diabetes Assoc We have explored the role of individual elements of the hypothalamic pituitary adrenal axis on
the pathogenesis of hypoglycemia-associated autonomic failure. Five groups of male
Sprague-Dawley rats were used. Control animals had 3 days of sham treatment followed ... Cited by 39 - Related articles - BL Direct - All 6 versions
- ►physiology.org K Shum, K Inouye, O Chan, J Mathoo, D … - American Journal of …, 2001 - Am Physiological Soc This study aimed to differentiate the effects of repeated antecedent hypoglycemia, antecedent
marked hyperinsulinemia, and antecedent increases in corticosterone on counterregulation to
subsequent hypoglycemia in normal rats. Specifically, we examined whether exposure to ... Cited by 32 - Related articles - BL Direct - All 3 versions
- ►physiology.org SB Evans, CW Wilkinson, K Bentson, P … - American Journal of …, 2001 - Am Physiological Soc The mechanism(s) underlying hypoglycemia-associated autonomic failure (HAAF) are
unknown. To test the hypothesis that the activation of brain regions involved in the counterregulatory
response to hypoglycemia is blunted with HAAF, rats were studied in a 2-day protocol. ... Cited by 47 - Related articles - BL Direct - All 4 versions
B Raju, VP McGregor, PE Cryer - Diabetes, 2003 - Am Diabetes Assoc The concept of hypoglycemia-associated autonomic failure (HAAF) in diabetes posits that recent
antecedent iatrogenic hypoglycemia causes both defective glucose counterregulation (by reducing
the epinephrine response in the setting of an absent glucagon response) and ... Cited by 22 - Related articles - BL Direct - All 4 versions
- ►physiology.org VP McGregor, S Banarer, PE Cryer - American Journal of …, 2002 - Am Physiological Soc We tested the hypothesis that increased endogenous cortisol secretion reduces autonomic neuroendocrine
and neurogenic symptom responses to subsequent hypoglycemia. Twelve healthy young adults
were studied on two separate occasions, once after infusions of a pharmacological dose ... Cited by 31 - Related articles - BL Direct - All 5 versions
- ►physiology.org DA Sandoval, L Ping, RA Neill, B Gong, K … - American Journal of …, 2005 - Am Physiological Soc The aim of this study was to determine whether activation of central type II glucocorticoid receptors
can blunt autonomic nervous system counterregulatory responses to subsequent
hypoglycemia. Sixty conscious unrestrained Sprague-Dawley rats were studied during 2- ... Cited by 14 - Related articles - All 4 versions
- ►nih.gov [PDF] AM Powell, RS Sherwin, GI … - Journal of Clinical …, 1993 - pubmedcentral.nih.gov To evaluate the roles of iatrogenic hypoglycemia and diabetes per se in the pathogenesis of
defective hormonal counterregula- tion against hypoglycemia in insulin-dependent diabetes
melli- tus (IDDM), nondiabetic, and spontaneously diabetic BB/ Wor rats were studied ... Cited by 42 - Related articles - BL Direct - All 8 versions
SN Davis, S Mann, P Galassetti, RA Neill, D … - DIABETES-NEW …, 2000 - Am Diabetes Assoc N umerous studies have demonstrated that antecedent hypoglycemia can blunt subsequent
counterregulatory responses to hypoglycemia (1–7). Recent work has focused on determining
the in vivo factors and mechanisms responsible for this find- ing. Depth of antecedent ... Cited by 42 - Related articles - BL Direct - All 5 versions
