A Adkins, R Basu, M Persson, B Dicke, P … - Diabetes, 2003 - Am Diabetes Assoc To determine the mechanism(s) by which insulin inhibits endogenous glucose
production (EGP) in nondiabetic humans, insulin was infused at rates of 0.25,
0.375, or 0.5 mU · kg −1 · min −1 and glucose was clamped at ∼5.5 ... Cited by 30 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org A Gastaldelli, E Toschi, M Pettiti, S Frascerra … - Diabetes, 2001 - Am Diabetes Assoc Gluconeogenesis (GNG) is enhanced in type 2 diabetes. In experimental animals,
insulin at high doses decreases the incorporation of labeled GNG precursors into
plasma glucose. Whether physiological hyperinsulinemia has any effect on ... Cited by 63 - Related articles - BL Direct - All 5 versions
WC Schumann, A Gastaldelli, V Chandramouli, … - Analytical Biochemistry, 2001 - Elsevier 4. M. Roden, H. Stingl, V. Chandramouli, WC Schumann, A. Hofer, BR Landau, P.
Nowotny, W. Waldhausl and GI Shulman, Effects of free fatty acids elevation on
postabsorptive endogenous glucose production and gluconeogenesis in man. ... Cited by 30 - Related articles - BL Direct - All 3 versions
- ►shouxi.net R Basu, V Chandramouli, B Dicke, B Landau, … - Diabetes, 2005 - Am Diabetes Assoc To determine whether the hepatic insulin resistance of obesity and type 2
diabetes is due to impaired insulin-induced suppression of glycogenolysis as
well as gluconeogenesis, 10 lean nondiabetic, 10 obese nondiabetic, and 11 ... Cited by 25 - Related articles - All 5 versions
- ►physiology.org G Boden, X Chen, TP Stein - American Journal of Physiology- Endocrinology And …, 2001 - Am Physiological Soc We tested the generally accepted concept that increased gluconeogenesis (GNG)
and endogenous glucose production (EGP) are the main reasons for postabsorptive
hyperglycemia in patients with type 2 diabetes mellitus (T2DM). GNG was ... Cited by 76 - Related articles - BL Direct - All 3 versions
- ►physiology.org R Basu, WF Schwenk, RA Rizza - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc To determine whether regulation of fasting endogenous glucose production (EGP)
and glucose disappearance (R d ) are both abnormal in people with type 2
diabetes, EGP and R d were measured in 7 "severe" (SD), 9 "mild" (MD), and ... Cited by 28 - Related articles - All 3 versions
H Stingl, V Chandramouli, WC Schumann, A … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis: Glycogen cycling, ie simul- taneous glycogen synthesis
and glycogenolysis, affects estimates of glucose fluxes using tracer techniques
and may contribute to hyperglycaemia in diabetic conditions. This study ... Cited by 12 - Related articles - BL Direct - All 4 versions
DS Edgerton, S Cardin, M Emshwiller, D … - Diabetes, 2001 - Am Diabetes Assoc Based on our earlier work, a 2.5-fold increase in insulin secretion should
completely inhibit hepatic glucose production through the hormone's direct
effect on hepatic glycogen metabolism. The aim of the present study was to ... Cited by 67 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org G Bock, C Dalla Man, M Campioni, E … - Diabetes, 2007 - Am Diabetes Assoc To determine whether nonglucose nutrient–induced insulin secretion is impaired
in pre-diabetes, subjects with impaired or normal fasting glucose were studied
after ingesting either a mixed meal containing 75 g glucose or 75 g glucose ... Cited by 6 - Related articles - BL Direct - All 5 versions
O Kunert, H Stingl, E Rosian, M Krššák, E … - Diabetes, 2003 - Am Diabetes Assoc Several problems limit quantification of gluconeogenesis. We applied in vitro 2
H-nuclear magnetic resonance (NMR) spectroscopy to simultaneously measure 2 H in
all glucose carbons for direct assessment of gluconeogenesis. This method ... Cited by 17 - Related articles - BL Direct - All 4 versions
