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Scholar Results 1 - 10 of about 101 related to Lerín: Regulation and function of the muscle glycogen-targeting subunit of protein phosphatase.... (0.10 sec) 

Regulation and function of the muscle glycogen-targeting subunit of protein …

- diabetesjournals.org
C Lerín, E Montell, T Nolasco, C Clark, MJ Brady, CB … - Diabetes, 2003 - Am Diabetes Assoc
G M , the muscle-specific glycogen-targeting subunit of protein phosphatase 1 (PP1) targeted
to the sarcoplasmic reticulum, was proposed to regulate recovery of glycogen in exercised
muscle, whereas mutation truncation of its COOH-terminal domain is known to be ...
Cited by 8 - Related articles - BL Direct - All 4 versions

[PDF] Regulation and Function of the Muscle Glycogen-Targeting Subunit of Protein …


C Lerın, E Montell, T Nolasco, C Clark, MJ Brady, CB … - Diabetes, 2003 - Am Diabetes Assoc
Page 1. Regulation and Function of the Muscle Glycogen-Targeting Subunit of Protein
Phosphatase 1 (G M ) in Human Muscle Cells Depends on the COOH-Terminal Region
and Glycogen Content Carlos Lerın 1 Eula`lia Montell ...
Cited by 1 - Related articles

Gene structure and expression of the targeting subunit, RGL, of the muscle-specific …


C Lannér, Y Suzuki, C Bi, H Zhang, LD Cooper, MM … - Archives of Biochemistry …, 2001 - Elsevier
The type I phosphatase associated with glycogen, PP1G, plays an important role in glycogen
metabolism. PP1G is targeted to glycogen by the R GL subunit, which regulates the function
of the enzyme. We report the cloning and characterization of the gene as well as the ...
Cited by 9 - Related articles - BL Direct - All 3 versions

21 The Genetic Basis of Diabetes


HQ Qu, C Polychronakos - Diabetes in Women: Pathophysiology and Therapy, 2009 - Springer
Genetic susceptibility to type 1 diabetes (DM1) and type 2 diabetes (DM2) is determined by complex
genetic factors. Until recently, only a few loci were known, but this is changing rapidly as a result
of the development of high-density genotyping arrays that have permitted genome-wide ...
Related articles - All 2 versions

Is hepatic glucose production increased in type 2 diabetes mellitus?


H Beck-Nielsen, O Hother-Nielsen, P Staehr - Current Diabetes Reports, 2002 - Springer
Based on recent studies, including our own, using what we consider to be an appropriate technique
to estimate rates of hepatic glucose production (HGP), this article can be summarized as
follows: 1) HGP in the overnight fasted state is near normal in obese type 2 diabetes ...
Cited by 10 - Related articles - All 3 versions

Interaction between glycogenin and glycogen synthase

- nih.gov [PDF] 
AV Skurat, AD Dietrich, PJ Roach - Archives of biochemistry and biophysics, 2006 - Elsevier
Glycogen synthase plays a key role in regulating glycogen metabolism. In a search for regulators
of glycogen synthase, a yeast two-hybrid study was performed. Two glycogen synthase-interacting
proteins were identified in human skeletal muscle, glycogenin-1, and nebulin. The ...
Cited by 1 - Related articles - All 5 versions

A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle …


DB Savage, L Zhai, B Ravikumar, CS Choi, JE … - PLoS …, 2008 - medicine.plosjournals.org
In this study we found a similar prevalence of the variant in an independent UK white population
of 744 participants (1.46%) and, using in vivo 13 C magnetic resonance spectroscopy
studies, demonstrate that human carriers (n = 6) of the variant have low basal (65% lower, ...
Cited by 1 - Related articles - Cached - All 11 versions

The prol 2 ala variant of the PPARG gene is a risk factor for peroxisome proliferator …


L HANSEN, CT EKSTRØM, R TABANERA Y … - The Journal of clinical …, 2006 - cat.inist.fr
Context: Activation of peroxisome proliferator-activated receptors(PPARs)-γ by
thiazolidinediones(pioglitazone, rosiglitazone) and dual-acting PPARα/γ agonists(pargluva,
ragaglitazar) is a widely used pharmacological principle to treat insulin resistance and ...
Cited by 1 - Related articles

Phenotype of a patient with a de novo mutation in the hepatocyte nuclear factor 1β/ …


C Mayer, Y Böttcher, P Kovacs, J Halbritter, … - Metabolism, Clinical …, 2008 - 万方数据资源系统
Mutations in the gene encoding the transcription factor hepatocyte nuclear factor (HNF) 1beta
cause various phenotypes including maturity-onset diabetes of the young type 5 (MODY5) and
kidney disease. We provide molecular and pathophysiologic characterization of a ...
Cited by 1 - Related articles - All 13 versions

Effects of insulin and transgenic overexpression of UDP-glucose …


TH Reynolds IV, Y Pak, TE Harris, J Manchester, EJ … - Journal of Biological …, 2005 - ASBMB
UDP-glucose (UDP-Glc) and glycogen levels in skeletal muscle fibers of defined fiber type were
measured using microanalytical methods. Infusing rats with insulin increased glycogen in both
Type I and Type II fibers. Insulin was without effect on UDP-Glc in Type I fibers but ...
Cited by 2 - Related articles - All 6 versions


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