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Scholar Results 1 - 10 of about 101 related to Lamhamedi-Cherradi: Critical Roles of Tumor Necrosis Factor–Related Apoptosis-Inducing.... (0.13 sec) 

Critical Roles of Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand in Type 1 …


SE Lamhamedi-Cherradi, S Zheng, RM Tisch … - Diabetes, 2003 - Am Diabetes Assoc
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)
selectively induces apoptosis of tumor cells but not most normal cells. Its
roles in normal nontransformed tissues are not clear. To explore the ...
Cited by 66 - Related articles - BL Direct - All 9 versions

Blockade of tumor necrosis factor-related apoptosis-inducing ligand exacerbates type 1 …


QS Mi, D Ly, SE Lamhamedi-Cherradi, KV … - Diabetes, 2003 - Am Diabetes Assoc
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is
expressed in different tissues and cells, including pancreas and lymphocytes,
and can induce apoptosis in various tumor cells but not in most normal ...
Cited by 50 - Related articles - BL Direct - All 4 versions

TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L suppresses experimental autoimmune …


E Cretney, JL McQualter, N Kayagaki, H … - Immunology and cell biology, 2005 - nature.com
Studies have suggested that endogenous TNF-related apoptosis-inducing ligand
(TRAIL)/Apo2L may suppress the induction of some autoimmune diseases in mice.
Here, we show that TRAIL/Apo2L suppresses autoimmune damage in relapsing- ...
Cited by 23 - Related articles - BL Direct - All 5 versions

TNF-related apoptosis-inducing ligand death pathway-mediated human beta-cell …


D Ou, D Metzger, X Wang, J Huang, P Pozzilli, … - Diabetologia, 2002 - Springer
Aims/hypothesis. The aim of this study is to investi- gate whether apoptosis in
human beta cells can be related to the induction of the tumor necrosis factor-
related apoptosis-inducing ligand (TRAIL) pathway. Methods. We examined the ...
Cited by 30 - Related articles - BL Direct - All 3 versions

Roles of TNF-related apoptosis-inducing ligand in experimental autoimmune …

- jimmunol.org
B Hilliard, A Wilmen, C Seidel, TST Liu, R … - The Journal of Immunology, 2001 - Am Assoc Immnol
TRAIL, the TNF-related apoptosis-inducing ligand, induces apoptosis of tumor
cells, but not normal cells; the roles of TRAIL in nontransformed tissues are
unknown. Using a soluble TRAIL receptor, we examined the consequences of ...
Cited by 133 - Related articles - BL Direct - All 3 versions

[PDF] Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL−/− mice


SE Lamhamedi-Cherradi, SJ Zheng, KA … - Nature Immunology, 2003 - imunologia.weblog.com.pt
TRAIL, the tumor necrosis factor-related apoptosis-inducing ligand, selectively
induces apoptosis of tumor cells, but not most normal cells. Its role in normal,
nontransformed tissues is not clear.We report here that mice deficient in ...
Cited by 204 - Related articles - BL Direct - All 4 versions

Regulation of soluble and surface-bound TRAIL in human T cells, B cells, and monocytes


S Ehrlich, C Infante-Duarte, B Seeger, F Zipp - Cytokine, 2003 - Elsevier
In this study, we have analyzed the regulation of TRAIL surface expression and
secretion in human T cells, B cells, and monocytes in response to specific
stimuli. T cells, B cells, and monocytes were cultured in the presence of ...
Cited by 45 - Related articles - All 4 versions

Normal thymocyte negative selection in TRAIL-deficient mice

- rupress.org
E Cretney, AP Uldrich, SP Berzins, A Strasser … - Journal of Experimental Medicine, 2003 - jem.rupress.org
The molecular basis of thymocyte negative selection, which plays a critical role
in establishing and maintaining immunological tolerance, is not yet resolved. In
particular, the importance of the death receptor subgroup of the tumor ...
Cited by 56 - Related articles - BL Direct - All 5 versions

Tumor necrosis factor-related apoptosis-inducing ligand and CD56 expression in patients …


SC Cheung, DL Metzger, X Wang, J Huang, J … - Pancreas, 2005 - journals.lww.com
Objectives: Our previous report showed that b-cell antigen–specific CD56+
T-cells and cytokine TRAIL mediate destruction of human pancreatic b cells in
vitro. To determine whether CD56 and TRAIL are present during islet cell ...
Cited by 13 - Related articles - All 3 versions

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis …

- jbc.org
J Morel, R Audo, M Hahne, B Combe - Journal of Biological Chemistry, 2005 - ASBMB
A hallmark of rheumatoid arthritis (RA) is the pseudo-tumoral expansion of
fibroblast-like synoviocytes (FLSs), and the RA FLS has therefore been proposed
as a therapeutic target. Tumor necrosis factor (TNF)-related ...
Cited by 74 - Related articles - All 6 versions


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