CR Bruce, AL Carey, JA Hawley, MA Febbraio - Diabetes, 2003 - Am Diabetes Assoc To examine whether genes associated with cellular defense against oxidative stress are associated
with insulin sensitivity, patients with type 2 diabetes (n = 7) and age-matched (n = 5) and young
(n = 9) control subjects underwent a euglycemic-hyperinsulinemic clamp for 120 min. ... Cited by 87 - Related articles - BL Direct - All 4 versions
DAD Mechanism - Diabetes, 2003 - Am Diabetes Assoc Page 1. Intramuscular Heat Shock Protein 72 and Heme Oxygenase-1 mRNA Are
Reduced in Patients With Type 2 Diabetes Evidence That Insulin Resistance Is
Associated With a Disturbed Antioxidant Defense Mechanism ... Related articles - All 2 versions
- ►diabetesjournals.org I Kurucz, Á Morva, A Vaag, KF Eriksson, X Huang, L … - Diabetes, 2002 - Am Diabetes Assoc Oxidative stress has been ascribed a role in the pathogenesis of diabetes and its
complications, and stress proteins have been shown to protect organisms in vitro and in vivo
against oxidative stress. To study the putative role of one of the most abundant ... Cited by 46 - Related articles - BL Direct - All 4 versions
- ►physiology.org NG Abraham, R Rezzani, L Rodella, A … - American Journal of …, 2004 - Am Physiological Soc Heme oxygenase (HO)-1 represents a key defense mechanism against oxidative injury. Hyperglycemia
produces oxidative stress and various perturbations of cell physiology. The effect of streptozotocin
(STZ)-induced diabetes on aortic HO activity, heme content, the number of circulating ... Cited by 59 - Related articles - All 4 versions
- ►nih.gov J Chung, AK Nguyen, DC Henstridge, AG … - Proceedings of the …, 2008 - National Acad Sciences Patients with type 2 diabetes have reduced gene expression of heat shock protein (HSP) 72,
which correlates with reduced insulin sensitivity. Heat therapy, which activates HSP72, improves
clinical parameters in these patients. Activation of several inflammatory signaling proteins ... Cited by 30 - Related articles - BL Direct - All 8 versions
S Quan, PM Kaminski, L Yang, T Morita, M Inaba, S … - … and Biophysical Research …, 2004 - Elsevier Heme oxygenase-1 (HO-1) represents a key defense mechanism against oxidative injury. Hyperglycemia
has been linked to increased oxidative stress, leading to endothelial dysfunction, delayed cell
replication, and enhanced apoptosis. The effect of streptozotocin (STZ)-induced diabetes ... Cited by 48 - Related articles - All 4 versions
- ►physiology.org M Atalay, NKJ Oksala, DE Laaksonen, S … - Journal of Applied …, 2004 - Am Physiological Soc Strenuous exercise induces oxidative stress and modification of intracellular proteins. Exercise
training, however, upregulates endogenous antioxidant defenses and heat shock protein
(HSP) expression. In diabetes, perturbations in the endogenous antioxidant and HSP ... Cited by 58 - Related articles - BL Direct - All 7 versions
PL Hooper - New England Journal of Medicine, 1999 - content.nejm.org To the Editor: Physical exercise is effective therapy for patients with type 2 diabetes mellitus.
Therefore, my colleagues and I asked the following question: Would the effects of partial immersion
in a hot tub simulate the beneficial effects of exercise? We asked eight patients (five men ... Cited by 24 - Related articles - All 5 versions
M Kurthy, T Mogyorosi, K Nagy, T … - ANNALS-NEW …, 2002 - interscience.wiley.com Abstract: Bimoclomol (BML), a symptomatic antidiabetic agent, has been developed by Biorex
R & D Co. to treat diabetic neuropathy and retinopathy. BRX-220, an orally active member of
the BRX family, has been developed to treat diabetic complications and insulin resistance ... Cited by 15 - Related articles - BL Direct - All 3 versions
