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Scholar Results 1 - 10 of about 101 related to Shaw: S100B-RAGE-mediated augmentation of angiotensin II-induced activation of JAK2 in vascular.... (0.16 sec) 

S100B-RAGE-mediated augmentation of angiotensin II-induced activation of JAK2 …

- diabetesjournals.org
SS Shaw, AM Schmidt, AK Banes, X Wang, DM Stern, … - Diabetes, 2003 - Am Diabetes Assoc
Angiotensin II (Ang II), a vasoactive peptide that is also considered a growth factor, has been
implicated in both normal and diabetic cellular proliferation. We recently found that activation
of janus kinase 2 (JAK2) is essential for the Ang II–induced proliferation of vascular ...
Cited by 52 - Related articles - BL Direct - All 4 versions

Key role of Src kinase in S100B-induced activation of the receptor for advanced …

- jbc.org
MA Reddy, SL Li, S Sahar, YS Kim, ZG Xu, L … - Journal of Biological …, 2006 - ASBMB
The receptor for advanced glycation end products (RAGE) and its ligands have been implicated
in the activation of oxidant stress and inflammatory pathways in vascular smooth muscle cells
(VSMCs) leading to the initiation and augmentation of atherosclerosis. Here we report ...
Cited by 40 - Related articles - All 5 versions

High glucose augments the angiotensin II-induced activation of JAK2 in vascular …


S Shaw, X Wang, H Redd, GD Alexander, CM … - Journal of Biological …, 2003 - ASBMB
Angiotensin II (Ang II), protein kinase C (PKC), reactive oxygen species (ROS) generated by
NADPH oxidase, the activation of Janus kinase 2 (JAK2), and the polyol pathway play important
parts in the hyperproliferation of vascular smooth muscle cells (VSMC), a characteristic ...
Cited by 55 - Related articles - BL Direct - All 4 versions

Angiotensin II-Induced Signaling Pathways in Diabetes


MB Marrero, D Fulton, D Stepp, DM … - Current Diabetes Reviews, 2005 - ingentaconnect.com
Abstract: Excessive cellular proliferation is a major contributor to the pathological changes associated
with the secondary complications of diabetes. In particular, hyperglycemia (HG)-induced growth
of vascular smooth muscle cells (VSMC) and glomerular mesangial cells (GMC) are ...
Cited by 2 - Related articles - BL Direct - All 2 versions

S100B potently activates p65/c-Rel transcriptional complexes in hippocampal …


D Kögel, M Peters, HG König, SMA Hashemi, NT Bui, V … - Neuroscience, 2004 - Elsevier
Increased serum levels of S100B are positively correlated with multiple forms of CNS
damage, such as stroke, CNS trauma and neurodegenerative diseases, but also in psychiatric
disorders. However, it is currently not known whether increased serum levels of S100B ...
Cited by 30 - Related articles - All 4 versions

Regulation of mesangial chloride channels by insulin and glucose: role in diabetic …


BN Ling - Clinical and experimental pharmacology & physiology, 1996 - ncbi.nlm.nih.gov
1. In response to vasoactive peptides (eg angiotensin II (AngII), vasopressin, endothelin-1,
platelet-activating factor), glomerular mesangial cell contraction is mediated through activation
of a Ca2+-dependent Cl- conductance that, in turn, promotes membrane depolarization ...
Cited by 15 - Related articles - BL Direct - All 3 versions

Phosphatidylinositol 3'-kinase-dependent activation of renal mesangial cell Ki-Ras …

- jbc.org
D Xu, JM Kyriakis - Journal of Biological Chemistry, 2003 - ASBMB
Advanced glycation end products (AGEs) are produced by the non-enzymatic glycation of proteins
and lipids. AGE levels are pathologically elevated in a number of inflammatory diseases and
in diabetes mellitus. There is evidence that AGEs, acting through the receptor for AGEs, ...
Cited by 31 - Related articles - BL Direct - All 5 versions

Incadronate disodium inhibits advanced glycation end products-induced …


T Okamoto, S Yamagishi, Y Inagaki, S Amano, M … - … and Biophysical Research …, 2002 - Elsevier
We have previously shown that advanced glycation end products (AGE), senescent macroprotein
derivatives formed at an accelerated rate in diabetes, induced angiogenesis through overgeneration
of autocrine vascular endothelial growth factor (VEGF). In the present study, effects of ...
Cited by 32 - Related articles - BL Direct - All 7 versions

Glutamate uptake is stimulated by extracellular S100B in hippocampal astrocytes


F Tramontina, AC Tramontina, DF Souza, MC Leite, … - Cellular and molecular …, 2006 - Springer
Page 1. Cellular and Molecular Neurobiology, Vol. 26, No. 1, February 2006 ( C 2006) DOI:
10.1007/s10571-006-9099-8 Glutamate Uptake Is Stimulated by Extracellular S100B in
Hippocampal Astrocytes Francine Tramontina, 1 Ana Carolina Tramontina, 1 Daniela F. Souza, ...
Cited by 18 - Related articles - BL Direct - All 4 versions

Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced …


X Wang, S Shaw, F Amiri, DC Eaton, MB Marrero - Diabetes, 2002 - Am Diabetes Assoc
High glucose (HG) causes glomerular mesangial cell (GMC) growth, production of transforming
growth factor (TGF)-β, and increased synthesis of matrix proteins such as fibronectin, contributing
to diabetic nephropathy. We recently found that exposure of cells to HG also activates the ...
Cited by 72 - Related articles - BL Direct - All 4 versions


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