RS Lindsay, T Funahashi, J Krakoff, Y Matsuzawa, S … - Diabetes, 2003 - Am Diabetes Assoc Adiponectin is a circulating protein secreted by adipocytes and is thought to have insulin-sensitizing
effects. We present genetic analysis of adiponectin levels in 517 Pima Indians without diabetes
(from 162 families, 750 sib-pairs). Adiponectin concentrations were heritable, with 39% of ... Cited by 66 - Related articles - BL Direct - All 4 versions
- ►endojournals.org LM Chuang, YF Chiu, W Sheu, YJ Hung, LT Ho, … - Journal of Clinical …, 2004 - Endocrine Soc Adiponectin is secreted by adipocytes and is thought to have insulin-sensitizing and antiatherogenic
effects. Two previous genome scans for plasma adiponectin have identified different regions
for European and Pima Indian populations. We here present multipoint linkage analysis ... Cited by 19 - Related articles - BL Direct - All 6 versions
- ►endojournals.org AG Comuzzie, T Funahashi, G Sonnenberg, LJ … - Journal of Clinical …, 2001 - Endocrine Soc Here we present the first genetic analysis of adiponectin levels, a newly identified
adipocyte-derived protein. Recent work has suggested that adiponectin may play a role in mediating
the effects of body weight as a risk factor for coronary artery disease. For this analysis we ... Cited by 209 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org TI Pollin, K Tanner, JR O'Connell, SH Ott, CM Damcott, … - Diabetes, 2005 - Am Diabetes Assoc We performed a genome-wide linkage scan of plasma adiponectin levels in 569 nondiabetic
participants in the Amish Family Diabetes Study. The highest logarithm of odds (LOD) score
(2.13; P = 0.0009) occurred on chromosome 3q27 between markers D3S1602 and ... Cited by 49 - Related articles - All 10 versions
- ►diabetesjournals.org X Guo, MF Saad, CD Langefeld, AH Williams, J Cui, KD … - Diabetes, 2006 - Am Diabetes Assoc Adiponectin (APM1) is an adipocyte-derived peptide that contributes to glucose, lipid, and energy
homeostasis. We assessed the genetic basis of plasma adiponectin in Hispanic-American and
African-American families enrolled through the Insulin Resistance Atherosclerosis Study ... Cited by 14 - Related articles - BL Direct - All 5 versions
- ►physiology.org C Menzaghi, T Ercolino, L Salvemini, A … - Physiological …, 2004 - Am Physiological Soc Adiponectin is a circulating enhancer of insulin action that is secreted by the adipose tissue.
In epidemiological studies, serum levels of this protein predict the risk of type 2 diabetes and
cardiovascular events. Serum adiponectin levels have been associated with variants at ... Cited by 35 - Related articles - All 4 versions
IM Heid, SA Wagner, H Gohlke, B Iglseder, JC Mueller, … - Diabetes, 2006 - Am Diabetes Assoc The associations of the adiponectin (APM1) gene with parameters of the metabolic syndrome
are inconsistent. We performed a systematic investigation based on fine-mapped single nucleotide
polymorphisms (SNPs) highlighting the genetic architecture and their role in modulating ... Cited by 53 - Related articles - BL Direct - All 6 versions
- ►endojournals.org NF Butte, AG Comuzzie, G Cai, SA Cole, NR … - Journal of Clinical …, 2005 - Endocrine Soc Objectives: The aims of these analyses were: 1) to estimate the heritability of fasting serum
adiponectin; 2) to evaluate the effects of age, sex, and body composition on fasting serum
adiponectin; 3) to test for associations between fasting serum adiponectin and diet, ... Cited by 33 - Related articles - BL Direct - All 9 versions
WS Yang, CA Hsiung, LT Ho, YT Chen, CT He, JD … - Diabetologia, 2003 - Springer Aims/hypothesis. Genetic interactions in modulating the phenotypes of a complex trait, such as
insulin sen- sitivity, were usually taken for granted. However, this has not been commonly
shown. Previous studies have suggested that both PPARγ2 and adiponectin genes could ... Cited by 38 - Related articles - BL Direct - All 6 versions
O Ukkola, E Ravussin, P Jacobson, L Sjöström, C … - Metabolism, 2003 - Elsevier Adiponectin (also called AdipoQ, gelatin-binding protein 28, Acrp30) DNA sequence variants
were determined in 96 unrelated female subjects with severe obesity (mean body mass index
[BMI], 42.3 kg/m 2 ) and in 96 non-obese female controls (mean BMI, 23.0 kg/m 2 ) from ... Cited by 51 - Related articles - All 12 versions
