A Flyvbjerg, L Denner, BF Schrijvers, RG Tilton, TH … - Diabetes, 2004 - Am Diabetes Assoc Advanced glycation end products (AGEs) have been implicated in the pathogenesis of diabetic
kidney disease. The actions of AGEs are mediated both through a non–receptor-mediated pathway
and through specific receptors for AGE (RAGEs). To explore a specific role for RAGE in ... Cited by 68 - Related articles - BL Direct - All 4 versions
- ►amjpathol.org TM Wendt, N Tanji, J Guo, TR Kislinger, W Qu, Y Lu, … - American Journal of …, 2003 - ASIP Diabetic nephropathy ensues from events involving earliest changes in the glomeruli and
podocytes, followed by accumulation of extracellular matrix in the mesangium. Postulated mechanisms
include roles for vascular endothelial growth factor (VEGF), produced by podocytes and ... Cited by 250 - Related articles - BL Direct - All 4 versions
- ►fasebj.org [PDF] JM Forbes, V Thallas, MC Thomas, HW Founds, WC … - The FASEB Journal, 2003 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.02-1102fje. Published online
July 18, 2003. The breakdown of pre-existing advanced glycation end products is
associated with reduced renal fibrosis in experimental diabetes ... Cited by 127 - Related articles - BL Direct - All 5 versions
JL Figarola, S Scott, S Loera, C Tessler, P Chu, L … - Diabetologia, 2003 - Springer Aims/hypothesis. Advanced glycation and lipoxidation endproducts have been implicated in
the pathogenesis of diabetic complications, including diabetic nephrop- athy. LR-90, a new advanced
glycation endproduct in- hibitor, was investigated for its effects on the develop- ment of ... Cited by 54 - Related articles - BL Direct - All 3 versions
V Thallas-Bonke, C Lindschau, B Rizkalla, LA Bach, G … - Diabetes, 2004 - Am Diabetes Assoc This study investigated the role of advanced glycation end products (AGEs) in mediating protein
kinase C (PKC) isoform expression in diabetic nephropathy. In vitro, vascular smooth muscle
cells incubated in a high-glucose (25-mmol/l) medium demonstrated translocation and ... Cited by 67 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org LJN Jensen, L Denner, BF Schrijvers, RG … - Journal of …, 2006 - Soc Endocrinology Advanced glycation endproducts (AGEs) have been implicated in the pathogenesis of diabetic
kidney disease. The actions of AGEs are mediated both through a non-receptor mediated pathway
and through specific receptors for AGEs (eg RAGE). To explore a potentially specific role ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►nih.gov Y Yamamoto, I Kato, T Doi, H Yonekura, S … - Journal of Clinical …, 2001 - Am Soc Clin Investig Vascular complications arising from multiple environmental and genetic factors are responsible
for many of the disabilities and short life expectancy associated with diabetes mellitus. Here we
provide the first direct in vivo evidence that interactions between advanced glycation end ... Cited by 269 - Related articles - BL Direct - All 7 versions
BJ Davis, JM Forbes, MC Thomas, G Jerums, WC … - Diabetologia, 2004 - Springer Aims/hypothesis. Diabetic renal disease has been pos- tulated to progress as a result of an interaction
be- tween metabolic and haemodynamic pathways. Our aim was to assess the functional,
structural, molecular and cellular aspects of renal disease in an experimen- tal model of ... Cited by 53 - Related articles - BL Direct - All 6 versions
- ►jbc.org EA McRobert, M Gallicchio, G Jerums, ME Cooper, … - Journal of Biological …, 2003 - ASBMB The presence of advanced glycation end products (AGEs) formed because of hyperglycemia
in diabetic patients has been strongly linked to the development of diabetic complications and
disturbances in cellular function. In this report, we describe the isolation and identification ... Cited by 33 - Related articles - BL Direct - All 4 versions
H Tsuji, N Iehara, T Masegi, M Imura, J Ohkawa, H … - … and Biophysical Research …, 1998 - Elsevier Accumulation of extracellular matrix is a characteristic of diabetic nephropathy, and advanced
glycation end products (AGEs) are considered to play an important role in the mechanism. To
investigate the involvement of the receptor for AGE (RAGE) in upregulation of type IV ... Cited by 44 - Related articles - BL Direct - All 5 versions
