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Scholar Results 1 - 10 of about 101 related to Raza: Elevated mitochondrial cytochrome P450 2E1 and glutathione S-transferase A4-4 in streptozot.... (0.09 sec) 

Elevated mitochondrial cytochrome P450 2E1 and glutathione S-transferase A4-4 …

- diabetesjournals.org
H Raza, SK Prabu, MA Robin, NG Avadhani - Diabetes, 2004 - Am Diabetes Assoc
Oxidative stress is an important factor in the etiology and pathogenesis of diabetes. We investigated
changes in mitochondrial production of reactive oxygen species (ROS) and mitochondrial antioxidant
defense systems in different tissues of streptozotocin (STZ)-induced diabetic rats. Our ...
Cited by 52 - Related articles - BL Direct - All 3 versions

Mitochondrial targeted cytochrome P450 2E1 (P450 MT5) contains an intact N …

- jbc.org
MA Robin, HK Anandatheerthavarada, JK Fang, M … - Journal of Biological …, 2001 - ASBMB
Hepatic mitochondria contain an inducible cytochrome P450, referred to as P450 MT5, which
cross-reacts with antibodies to microsomal cytochrome P450 2E1. In the present study, we
purified, partially sequenced, and determined enzymatic properties of the rat liver ...
Cited by 39 - Related articles - BL Direct - All 3 versions

[CITATION] Subcellular Oxidative Stress in Streptozotocin-induced Diabetic Rat Tissues


H Raza, A John, NG Avadhani
Related articles

Accumulation of Mitochondrial P450MT2, NH2-terminal Truncated Cytochrome …


… HK Anandatheerthavarada, SV Bhagwat, G Biswas … - Journal of Biological …, 2000 - ASBMB
The biochemical and molecular characteristics of cytochrome P4501A1 targeted to rat brain mitochondria
was studied to determine the generality of the targeting mechanism previously described for
mitochondrial cytochrome P450MT2 (P450MT2) from rat liver. In rat brain and C6 glioma ...
Cited by 21 - Related articles - BL Direct - All 4 versions

Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an …


MA Robin, HK Anandatheerthavarada, G Biswas, … - Journal of Biological …, 2002 - ASBMB
Cytochrome P450 2E1 (CYP2E1) plays an important role in alcohol-induced toxicity and oxidative
stress. Recently, we showed that this predominantly microsomal protein is also localized in rat
hepatic mitochondria. In this report, we show that the N-terminal 30 amino acids of ...
Cited by 67 - Related articles - BL Direct - All 3 versions

Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial …


C Demeilliers, C Maisonneuve, A Grodet, A Mansouri, … - Gastroenterology, 2002 - Elsevier
This article is not included in your organization's subscription. However, you may be able to access
this article under your organization's agreement with Elsevier. ... Background & Aims: A single
dose of alcohol causes transient hepatic mitochondrial DNA (mtDNA) depletion in mice ...
Cited by 50 - Related articles - BL Direct - All 12 versions

Identification of Sequences Responsible for Intracellular Targeting and Membrane …


EPA Neve, M Hidestrand, M Ingelman-Sundberg - Biochemistry, 2003 - pubs.acs.org
Because you do not have JavaScript enabled, the Quick Search functionality is not displayed
here. Please enable JavaScript or use the Advanced Search Page. ... This study was supported
by grants from the Swedish Research Council. ... Present address: Ludwig Institute for ...
Cited by 7 - Related articles - BL Direct - All 2 versions

Glutathione metabolism and oxidative stress in neonatal rat tissues from …


H Raza, A John - Diabetes/Metabolism Reviews - interscience.wiley.com
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In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ...
Cited by 7 - Related articles - BL Direct - All 3 versions

Identification and characterization of a mitochondrial targeting signal in rat …

- jbc.org
E Neve, M Ingelman-Sundberg - Journal of Biological Chemistry, 2001 - ASBMB
Cytochrome P450 2E1 (CYP2E1) lacking the hydrophobic NH 2 -terminal hydrophobic transmembrane
domain is specifically targeted to mitochondria, where it is processed to a soluble and catalytically
active form ( 2E1) with a mass of about 40 kDa. Small amounts of 2E1 were also ...
Cited by 28 - Related articles - BL Direct - All 3 versions

Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat …


MA Robin, I Sauvage, T Grandperret, V Descatoire, D … - FEBS letters, 2005 - Elsevier
Enhanced hepatic levels of cytochrome P450 2E1 (CYP2E1) may play a key role in the pathogenesis
of some liver diseases because CYP2E1 represents a significant source of reactive oxygen
species. Although a large fraction of CYP2E1 is located in the endoplasmic reticulum, ...
Cited by 14 - Related articles - All 5 versions


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