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Scholar Results 1 - 10 of about 101 related to Loomans: Endothelial Progenitor Cell Dysfunction. (0.08 sec) 

Endothelial Progenitor Cell Dysfunction

- diabetesjournals.org
CJM Loomans, EJP de Koning, FJT Staal, MB … - Diabetes, 2004 - Am Diabetes Assoc
Type 1 diabetes is associated with reduced vascular repair, as indicated by impaired wound
healing and reduced collateral formation in ischemia. Recently, endothelial progenitor cells
(EPCs) have been identified as important regulators of these processes. We therefore ...
Cited by 298 - Related articles - BL Direct - All 7 versions

Human endothelial progenitor cells from type II diabetics exhibit impaired …

- ahajournals.org
OM Tepper, RD Galiano, JM Capla, C Kalka, PJ Gagne … - Circulation, 2002 - Am Heart Assoc
Methods and Results— EPCs were isolated from human type II diabetics (n=20) and age-matched
control subjects (n=20). Proliferation of diabetic EPCs relative to control subjects was decreased
by 48% (P<0.01) and inversely correlated with patient levels of hemoglobin A1C ...
Cited by 672 - Related articles - BL Direct - All 8 versions

Hyperglycemia reduces survival and impairs function of circulating blood-derived …

- ahajournals.org
N Krankel, V Adams, A Linke, S Gielen, S … - … , and vascular biology, 2005 - Am Heart Assoc
Methods and Results— Peripheral blood mononuclear cells (MNCs) of healthy donors
(n=15) were cultivated under hyperglycemia (HG) conditions (12 mmol/L D-Glucose) or in osmotic
control medium (Con) (5 mmol/L D-Glucose plus 7 mmol/L L-Glucose) for 7 days. CPC ...
Cited by 88 - Related articles - All 7 versions

[PDF] Number and activity of endothelial progenitor cells from peripheral blood in …


C Jun Zhu, FR Zhang, TAO Qian Min, W Xing … - Clinical …, 2004 - cs.portlandpress.com
Hypercholesterolaemia contributes to atherosclerosis and coronary artery diseases by inducing
endothelial cell injury and dysfunction. Recent studies have provided increasing evidence that
EPCs (endothelial progenitor cells) participate in ongoing endothelial repair and ...
Cited by 89 - Related articles - View as HTML - BL Direct - All 10 versions

Impairment in ischemia-induced neovascularization in diabetes: bone marrow …

- amjpathol.org
R Tamarat, JS Silvestre, S Le Ricousse-Roussanne, … - American Journal of …, 2004 - ASIP
Mechanisms that hinder ischemia-induced neovascularization in diabetes remain poorly
understood. We hypothesized that endogenous bone marrow mononuclear cell (BM-MNC) dysfunction
may contribute to the abrogated postischemic revascularization reaction associated with ...
Cited by 95 - Related articles - BL Direct - All 5 versions

Circulating endothelial progenitor cells are reduced in peripheral vascular …

- onlinejacc.org
GP Fadini, M Miorin, M Facco, S Bonamico, I … - Journal of the American …, 2005 - Elsevier
Peripheral vascular disease is a common and severe complication of diabetes mellitus. Impaired
collateralization of diabetic vasculopathy has been extensively shown, but causes leading to
its pathogenesis are not fully understood. Recently, EPCs have been found to contribute ...
Cited by 165 - Related articles - All 17 versions

Smoking cessation rapidly increases circulating progenitor cells in peripheral …

- ahajournals.org
T Kondo, M Hayashi, K Takeshita, Y … - … , and vascular biology, 2004 - Am Heart Assoc
Methods and Results— We examined the effects of chronic smoking and of smoking cessation
on EPC levels. Circulating EPCs were quantified by flow cytometry as CD45 low CD34 + CD133
+ (progenitor cells [PCs]) or CD45 low CD34 + CD133 + VEGFR2 + (EPCs) in 14 ...
Cited by 179 - Related articles - BL Direct - All 9 versions

Number and migratory activity of circulating endothelial progenitor cells inversely …

- ahajournals.org
M Vasa, S Fichtlscherer, A Aicher, K Adler, C … - Circulation …, 2001 - Am Heart Assoc
Abstract—Recent studies provide increasing evidence that postnatal neovascularization involves
bone marrow–derived circulating endothelial progenitor cells (EPCs). The regulation of EPCs
in patients with coronary artery disease (CAD) is unclear at present. Therefore, we ...
Cited by 1158 - Related articles - All 10 versions

p38 mitogen-activated protein kinase downregulates endothelial progenitor cells

- ahajournals.org
FH Seeger, J Haendeler, DH Walter, U Rochwalsky, J … - Circulation, 2005 - Am Heart Assoc
Methods and Results— EPCs of patients or healthy subjects were isolated from peripheral
blood. Incubation with glucose or TNF- dose-dependently reduced the number of EPCs
(79.9±1.3% and 74.3±8.1% of control; P<0.05, respectively). This reduction was not ...
Cited by 104 - Related articles - All 9 versions

Circulating endothelial progenitor cells, vascular function, and cardiovascular risk

- diegori.it [PDF] 
JM Hill, G Zalos, JPJ Halcox, WH Schenke, … - The New England …, 2003 - nejm.highwire.org
Results We observed a strong correlation between the number of circulating endothelial progenitor
cells and the subjects' combined Framingham risk factor score (r=–0.47, P=0.001). Measurement
of flow-mediated brachial-artery reactivity also revealed a significant relation between ...
Cited by 1479 - Related articles - BL Direct - All 14 versions


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