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Scholar Results 1 - 10 of about 101 related to Guo: Peroxisome proliferator-activated receptor-γ ligands inhibit TGF-β1-induced fibronectin.... (0.09 sec) 

Peroxisome proliferator-activated receptor-γ ligands inhibit TGF-β1-induced fibronectin …

- diabetesjournals.org
B Guo, D Koya, M Isono, T Sugimoto, A … - Diabetes, 2004 - Am Diabetes Assoc
The thiazolidinedione (TZD) class of antidiabetic drugs, which are ligands for
peroxisome proliferator-activated receptor (PPAR)- , has been shown to possess
potent anti-inflammatory and antineoplastic actions. Here, we show in ...
Cited by 84 - Related articles - BL Direct - All 6 versions

[PDF] Peroxisome proliferator-activated receptor-ligands inhibit TGF-1-induced fibronectin …


B Guo, D Koya, M Isono, T Sugimoto, A … - Diabetes, 2004 - Am Diabetes Assoc
The thiazolidinedione (TZD) class of antidiabetic drugs, which are ligands for
peroxisome proliferator–activated receptor (PPAR)- , has been shown to possess
potent anti-inflammatory and antineoplastic actions. Here, we show in ...
Cited by 11 - Related articles

Differential effects of peroxisome proliferator activated receptor-γ (PPARγ) ligands in …


RS Chana, AJ Lewington, NJ Brunskill - Kidney international, 2004 - nature.com
Peroxisome proliferator activated receptors (PPARs) are ligand-activated
transcription factors with multiple effects on target cell function. PPAR
activity is regulated by extracellular signal-regulated protein kinase ...
Cited by 32 - Related articles - All 7 versions

Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts

- asnjournals.org
S Zafiriou, SR Stanners, S Saad, TS Polhill, P … - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol
Peroxisome proliferator–activated receptor- (PPAR- ) agonists are increasingly
used in patients with diabetes, and small studies have suggested a beneficial
effect on renal function, but their effects on extracellular matrix (ECM) ...
Cited by 75 - Related articles - All 6 versions

Effect of the new thiazolidinedione-pioglitazone on the development of oxidative stress in …


A Gumieniczek - Life sciences, 2003 - Elsevier
Impaired homeostasis under diabetic conditions is connected with the increased
production of free radicals and deficiency of antioxidative systems. The aim of
this study was to analyze the effect of new oral antidiabetic ...
Cited by 27 - Related articles - All 5 versions

Upregulation of type I collagen by TGF-beta in mesangial cells is blocked by PPARgamma …

- physiology.org [PDF] 
F Zheng, A Fornoni, SJ Elliot, Y Guan, MD … - American Journal of Physiology- Renal Physiology, 2002 - Am Physiological Soc
10 other HighWire hosted articles, the first 5 are: This article has been cited
by ... [PDF] [Full Text] [Abstract] , April 1, 2007; 292 (4): C1361-C1369. Am J
Physiol Cell Physiol R. Mishra, L. Zhu, RL Eckert and MS Simonson TGF-beta- ...
Cited by 84 - Related articles - BL Direct - All 4 versions

Pioglitazone increases renal tubular cell albumin uptake but limits proinflammatory and …


S Zafiriou, SR Stanners, TS Polhill, P … - Kidney international, 2004 - nature.com
Pioglitazone caused a dose-dependent increase in tubular cell albumin uptake (P
< 0.0001). Despite the increase in albumin reabsorption, no concurrent increase
in inflammatory or profibrotic markers were observed. Exposure to LDL ...
Cited by 52 - Related articles - BL Direct - All 5 versions

Troglitazone suppresses the secretion of type I collagen by mesangial cells in vitro


RE Routh, JH Johnson, KJ McCarthy - Kidney international, 2002 - nature.com
Rat mesangial cells were grown in medium containing 5 mmol/L glucose, 30 mmol/L
glucose, or 5 mmol/L glucose plus 25 mmol/L mannitol. The cultures were either
left untreated, treated with 10 mol/L troglitazone (PPAR- ), or 100 mol/L ...
Cited by 58 - Related articles - BL Direct - All 4 versions

Pioglitazone attenuates TGF-β1-induction of fibronectin synthesis and its splicing variant in …


A Maeda, S Horikoshi, T Gohda, T Tsuge, K … - Cell Biology International, 2005 - Elsevier
The peroxisome proliferator-activated receptor (PPAR)γ is expressed not only in
adipose tissue but also in macrophages/monocytes and plays important roles in
acute/chronic inflammation. Transforming growth factor (TGF)-β is a common ...
Cited by 33 - Related articles - All 3 versions

Peroxisome proliferator-activated receptor γ inhibits transforming growth factor β-induced …


M Fu, J Zhang, X Zhu, DE Myles, TM Willson, … - Journal of Biological Chemistry, 2001 - ASBMB
Activation of peroxisome proliferator-activated receptor γ (PPARγ) after
balloon injury significantly inhibits VSMC proliferation and neointima
formation. However, the precise mechanisms of this inhibition have not been ...
Cited by 116 - Related articles - BL Direct - All 3 versions


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