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Scholar Results 1 - 10 of about 101 related to Xiang: Genome-wide search for type 2 diabetes/impaired glucose homeostasis susceptibility.... (0.11 sec) 

Genome-wide search for type 2 diabetes/impaired glucose homeostasis …


K Xiang, Y Wang, T Zheng, W Jia, J Li, L Chen, K Shen, … - Diabetes, 2004 - Am Diabetes Assoc
This genome-wide search for susceptibility genes to type 2 diabetes/impaired glucose homeostasis
(IGH) was performed on a relatively homogenous Chinese sample with a total number of 257
pedigrees and 385 affected sibpairs. Two regions showed significant linkage to type 2 ...
Cited by 2 - Related articles - All 2 versions

Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose …

- diabetesjournals.org
WC Hsueh, PL St Jean, BD Mitchell, TI Pollin, WC … - Diabetes, 2003 - Am Diabetes Assoc
We conducted a genome scan using a 10-cM map to search for genes linked to type 2 diabetes
in 691 individuals from a founder population, the Old Order Amish. We then saturated two regions
on chromosomes 1 and 14 showing promising linkage signals with additional markers to ...
Cited by 6 - Related articles - All 7 versions

[CITATION] American Diabetes Association GENNID Study Group: Genomewide search for …


MG Ehm, MC Karnoub, H Sakul, K Gottschalk, DC Holt, … - Am J Hum Genet, 2000
Cited by 18 - Related articles

Application of an ordered subset analysis approach to the genetics of alcoholism.


RM Watanabe, S Ghosh, G Birznieks, WL Duren, … - Genetic …, 1999 - ncbi.nlm.nih.gov
For complex diseases, underlying etiologic heterogeneity may reduce power to detect
linkage. Thus, methods to identify more homogeneous subgroups within a given sample in a
linkage study may improve detection of putative susceptibility loci. In this study we ...
Cited by 8 - Related articles - BL Direct

Subsets of Finns with high HDL to total cholesterol ratio show evidence for linkage …

- umich.edu [PDF] 
C Shtir, IS Nagakawa, WL Duren, KN Conneely, LJ … - Hum Hered, 2007 - content.karger.com
Objectives: The purpose of this study was to examine carefully heterogeneity underlying evidence
for linkage to type 2 diabetes (T2DM) on chromosome 6q from two sets of FUSION families.
Methods: Ordered subsets analysis (OSA) was performed on two sets of FUSION families. ...
Cited by 2 - Related articles - BL Direct - All 7 versions

[CITATION] A genome wide scan for loci predisposing to type 2 diabetes in vk population


S Wiltshire, AT Hattersley, GA Hitman, M Walker, JC … - Am J Hum Genet, 2001
Cited by 2 - Related articles

[PDF] The genetics of type 2 diabetes: A review


A Taylor - Int J Diabetes & Metabolism, 2006 - ijod.uaeu.ac.ae
Introduction Diabetes mellitus affects approximately 150 million people around the world. It is
forecasted that by 2025 this number would be doubled, with a prevalence that varies markedly
from population to population.1 Many causal factors have been identified which influence ...
Related articles - View as HTML - BL Direct - All 2 versions

Young-onset type 2 diabetes families are the major contributors to genetic loci in …


TM Frayling, S Wiltshire, GA Hitman, M Walker, JC Levy … - Diabetes, 2003 - Am Diabetes Assoc
A young onset of type 2 diabetes is likely to result, in part, from greater genetic susceptibility.
Young-onset families may therefore represent a group in which genes are more easily detectable
by linkage. To test this hypothesis, we conducted age at diagnosis (AAD) stratified linkage ...
Cited by 29 - Related articles - BL Direct - All 5 versions

Examination of candidate chromosomal regions for type 2 diabetes reveals a …


MG Pezzolesi, M Nam, T Nagase, T Klupa, JS Dunn, … - Diabetes, 2004 - Am Diabetes Assoc
In a panel of large Caucasian pedigrees, we genotyped markers in eight chromosomal regions
previously reported as supporting linkage with type 2 diabetes. We previously reported significant
linkage on chromosome 20q (maximum logarithm of odds score [MLS] = 2.79) in this ...
Cited by 15 - Related articles - BL Direct - All 4 versions

[PDF] Examination of Candidate Chromosomal Regions for Type 2 Diabetes Reveals a …


MG Pezzolesi, M Nam, T Nagase, T Klupa, JS Dunn, … - Diabetes, 2004 - Am Diabetes Assoc
Type 2 Diabetes Reveals a Susceptibility Locus on ... Marcus G. Pezzolesi, 1 Moonsuk
Nam, 1,2,4 Terumasa Nagase, 1,2 Tomasz Klupa, 1,2 Jonathon S. Dunn, 1 ... Wojciech M.
Mlynarski, 1,2 Stephen S. Rich, 3 James H. Warram, 1 and Andrzej S. Krolewski 1,2
Related articles - All 3 versions


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