- ►diabetesjournals.org WH Schott, BD Haskell, HM Tse, MJ Milton, JD … - Diabetes, 2004 - Am Diabetes Assoc Interleukin (IL)-1β and IL-18 are two cytokines associated with the
immunopathogenesis of diabetes in NOD mice. Both of these cytokines are cleaved
by caspase-1 to their biologically active forms. IL-1 is a proinflammatory ... Cited by 20 - Related articles - BL Direct - All 4 versions
[CITATION] IFN-γ sensitizes MIN6N8 cells insulinoma cells to TNF-α-induced apoptosis by inhibiting …
B Siegmund, M Zeitz - Rocz Akad Med Bialymst, 2004 - advms.pl Our understanding of the etiology and pathogenesis of IBD has improved
extensively over the past years. At the center of the pathogenesis seems to be
an excessive pro- inflammatory immune reaction towards normal intestinal ... Cited by 11 - Related articles - View as HTML - All 7 versions
HE Thomas, W Irawaty, R Darwiche, TC … - Diabetes, 2004 - Am Diabetes Assoc Proinflammatory cytokines are believed to be important in pancreatic β-cell
destruction in the development of type 1 diabetes. They act by upregulation of
genes including Fas and inducible nitric oxide synthase (iNOS), which have ... Cited by 50 - Related articles - BL Direct - All 4 versions
P Zaccone, J Phillips, I Conget, A Cooke, F … - Clinical Immunology, 2005 - Elsevier IL-18 is a type 1 pro-inflammatory cytokine with structural similarities to IL-1
and in synergy with IL-12 stimulates IFN-γ production from T lymphocytes and
polarizes development and function of Th1 cells. Because IL-1, IFN-γ, and ... Cited by 12 - Related articles - All 3 versions
- ►jimmunol.org Y Oikawa, A Shimada, A Kasuga, J Morimoto, T … - The Journal of Immunology, 2003 - Am Assoc Immnol IL-18 is now identified as a pleiotropic cytokine that acts as a cofactor for
both Th1 and Th2 cell development. Type 1 diabetes is considered a Th1-type
autoimmune disease, and to date, the suppressive effect of exogenous IL-18 ... Cited by 42 - Related articles - BL Direct - All 5 versions
F Nicoletti, RD Marco, G Papaccio, I Conget, … - European journal of immunology, 2003 - interscience.wiley.com IL-18 is a cytokine structurally and functionally related to IL-1 that, in
synergy with IL-12, stimulates the synthesis of IFN- from T lymphocytes and
natural killer cells. Because IFN- plays a key pathogenic role in the ... Cited by 26 - Related articles - BL Direct - All 3 versions
S Gangemi, RA Merendino, F Guarneri, PL … - Journal of the European Academy of Dermatology and …, 2003 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 18 - Related articles - All 5 versions
A Ide, E Kawasaki, N Abiru, F Sun, T … - Ann NY Acad Sci, 2003 - interscience.wiley.com Abstract: Type 1 diabetes is a heterogeneous autoimmune disease and is often
associated with other organ-specific autoimmune diseases, including autoimmune
thyroid disease (AITD). IL-18 is a potent proinflammatory cytokine capable ... Cited by 9 - Related articles - BL Direct - All 4 versions
E Ingelsson, J Saldeen, N Welsh - Immunology letters, 1998 - Elsevier The aim of the present study was to correlate the islet expression of the
apoptosis-associated factors Fas/Apo-1, FasL, ICE and perforin with the
progression of β-cell destruction in non-obese diabetic (NOD) mice. For ... Cited by 19 - Related articles - All 4 versions
