- ►tno.co.jp [PDF] AM van den Hoek, PJ Voshol, BN Karnekamp, … - Diabetes, 2004 - Am Diabetes Assoc Recent evidence demonstrates that hypothalamic insulin signaling is required for
inhibition of endogenous glucose production. The downstream mechanisms that are
responsible for the effects of hypothalamic insulin receptor activation on ... Cited by 31 - Related articles - BL Direct - All 7 versions
- ►tno.co.jp [PDF] AM van den Hoek, AC Heijboer, EPM Corssmit, … - Diabetes, 2004 - Am Diabetes Assoc Peptide YY 3–36 (PYY 3–36 ) is released by the gut in response to nutrient
ingestion. It modulates the activities of orexigenic neuropeptide Y (NPY)
neurons and anorexigenic proopiomelanocortin (POMC) neurons in the ... Cited by 41 - Related articles - BL Direct - All 5 versions
JL Marks, K Waite - Journal of neuroendocrinology, 1997 - interscience.wiley.com Acute administration of neuropeptide Y(NPY) into the hypothalamus and third
cerebral ventricle (ICV) increases respiratory quotient, reduces energy
expenditure and increases circulating, insulin, glucagon and ... Cited by 26 - Related articles - BL Direct - All 5 versions
- ►tno.co.jp [PDF] AC Heijboer, AM van den Hoek, H Pijl, PJ … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: The present study was con- ducted to evaluate the
effects of central administration of melanotan II (MTII), a melanocortin-3/4
receptor agonist, on hepatic and whole-body insulin sensitivity, ... Cited by 13 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org PJ Voshol, MC Jong, VEH Dahlmans, D Kratky … - Diabetes, 2001 - Am Diabetes Assoc In patients with type 2 diabetes, a strong correlation between accumulation of
intramuscular triclycerides (TGs) and insulin resistance has been found. The aim
of the present study was to determine whether there is a causal relation ... Cited by 66 - Related articles - BL Direct - All 9 versions
RW Gelling, GJ Morton, CD Morrison, KD … - Cell Metabolism, 2006 - Elsevier To investigate the role of brain insulin action in the pathogenesis and
treatment of diabetes, we asked whether neuronal insulin signaling is required
for glucose-lowering during insulin treatment of diabetes. Hypothalamic ... Cited by 33 - Related articles - All 8 versions
AC Heijboer, PJ Voshol, E Donga, CG van … - Peptides, 2005 - Elsevier The hypothalamic circuitry, apart from its impact on food intake, modulates
insulin sensitivity to adapt metabolic conditions in the face of environmental
fluctuations in nutrient availability. The purpose of the present study was ... Cited by 10 - Related articles - All 3 versions
- ►jneurosci.org NS Singhal, MA Lazar, RS Ahima - Journal of Neuroscience, 2007 - Soc Neuroscience Sensing of peripheral hormones and nutrients by the hypothalamus plays an
important role in maintaining peripheral glucose homeostasis. The hormone
resistin impairs the response to insulin in liver and other peripheral ... Cited by 11 - Related articles - All 3 versions
YB Shrestha, K Wickwire, SQ Giraudo - Neuroreport, 2004 - journals.lww.com Ghrelin is a 28 amino-acid peptide that has been shown to induce positive energy
balance when administered both peripherally and centrally. This effect appears
to occur by increasing food intake and by reducing fat utilization. Ghrelin ... Cited by 14 - Related articles - BL Direct - All 3 versions
- ►cell.com GJ Morton, RW Gelling, KD Niswender, CD … - Cell Metabolism, 2005 - Elsevier To investigate whether phosphatidylinositol-3 kinase (PI3K) signaling mediates
the metabolic effects of hypothalamic leptin action, adenoviral gene therapy was
used to direct expression of leptin receptors to the area of the ... Cited by 64 - Related articles - All 9 versions
