- ►diabetesjournals.org S Nejentsev, JD Cooper, L Godfrey, JMM Howson, H … - Diabetes, 2004 - Am Diabetes Assoc Vitamin D is known to modulate the immune system, and its administration has been associated
with reduced risk of type 1 diabetes. Vitamin D acts via its receptor (VDR). Four single nucleotide
polymorphisms (SNPs) of the VDR gene have been commonly studied, and evidence of ... Cited by 43 - Related articles - BL Direct - All 4 versions
- ►eje-online.org [PDF] H Turpeinen, R Hermann, S Vaara, AP Laine, O … - European Journal of …, 2003 - EFES Hannu Turpeinen, Robert Hermann, Satu Vaara, Antti-Pekka Laine, Olli Simell1, Mikael
Knip2,3, Riitta Veijola4 and Jorma Ilonen JDRF Centre for Prevention of Type 1 Diabetes in Finland
and Departments of Virology and 1Paediatrics, University of Turku, Turku, Finland, ... Cited by 33 - Related articles - BL Direct - All 7 versions
B Angel, JL Santos, E Carrasco, C Albala, F Perez- … - European journal of …, 2004 - Springer Abstract. Several reports have found a relation between polymorphisms of the vitamin D receptor
gene (VDR) and the development of type 1 diabetes. We have examined the association of three
VDR polymorphism with type 1 diabetes in 59 Chilean case-parents trios. Genotyping for ... Cited by 14 - Related articles - All 7 versions
WJ Fassbender, B Goertz, K Weismuller, B … - Hormone and …, 2002 - thieme-connect.com Type 1 diabetic individuals are known to develop disorders of bone metabolism resulting in
osteopenia. Previous studies have suggested an influence of vitamin D receptor alleles on bone
metabolism and susceptibility for type 1 diabetes mellitus. The present study was initiated ... Cited by 36 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org SW Guo, VL Magnuson, JJ Schiller, X Wang, … - American journal of …, 2006 - Oxford Univ Press Several polymorphisms in the vitamin D receptor (VDR) gene have been reported to be associated
with the risk of developing type 1 diabetes, yet published findings have been conflicting. In this
study, the authors attempted to evaluate the evidence regarding the association. They ... Cited by 24 - Related articles - BL Direct - All 12 versions
C Guja, S Marshall, K Welsh, M Merriman, … - Journal of Cellular …, 2002 - interscience.wiley.com Several studies suggested that part of the genetic susceptibility for Type 1 diabetes (TIDM) is
encoded by some polymorphisms of CTLA-4 gene (2q33) and of Vitamin D Receptor gene
(VDR; 12q12-14). Our aim was to assess their contribution to TIDM genetic susceptibility ... Cited by 29 - Related articles - BL Direct - All 3 versions
- ►eje.org [PDF] B Gyorffy, B Vasarhelyi, D Krikovszky, L Madacsy, A … - European journal of …, 2002 - eje.org Objective: Recent data have indicated the significance of vitamin D receptor (VDR) polymorphisms
in type 1 diabetes mellitus (T1DM). We have studied the association of five known restriction
enzyme polymorphisms of the VDR gene in patients with T1DM. Design and Methods: ... Cited by 41 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org [PDF] I Yokota, S Satomura, S Kitamura, Y Taki, E Naito, … - Diabetes care, 2002 - Am Diabetes Assoc 1,25-dihydroxyvitamin D3[1,25(OH)2D3] not only regulates calcium metabolism but also modulates
the immune system. Some reports have suggested that 1,25(OH)2D3 helps to prevent the
devel- opment of type 1 diabetes. The associa- tion between the vitamin D receptor (VDR) ... Cited by 21 - Related articles - BL Direct - All 5 versions
BPC Koeleman, G Valdigem, P Eerligh, MJ Giphart, BO … - The Lancet, 2002 - Elsevier Four major variants of the vitamin D receptor gene have been identified: FokI in exon 2, BsmI
and ApaI in intron 8, and a silent TaqI variant in exon 9. FokI is the only variant resulting in an
alternative transcription initiation site leading to an expressed protein variant. Functional ... Cited by 11 - Related articles - All 5 versions
V Škrabić, T Zemunik, M Šitum, J Terzić - Diabetes research and clinical …, 2003 - Elsevier Several studies have found a relationship between polymorphisms of the vitamin D receptor
gene (VDR) and development of type 1 diabetes (T1DM). The meaning of this observation remains
unclear and its relevance must be checked in different population samples. To examine ... Cited by 43 - Related articles - All 11 versions
