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Scholar Results 1 - 10 of about 101 related to Ellmerer: Physiological hyperinsulinemia in dogs augments access of macromolecules to insulin-sen.... (0.15 sec) 

Physiological hyperinsulinemia in dogs augments access of macromolecules to insulin- …

- diabetesjournals.org
M Ellmerer, SP Kim, M Hamilton-Wessler, K … - Diabetes, 2004 - Am Diabetes Assoc
Pharmacological doses of insulin increase limb blood flow and enhance tissue
recruitment for small solutes such as glucose. We investigated whether elevating
insulin within the physiological range (68 ± 6 vs. 425 ± 27 pmol/l) can ...
Cited by 11 - Related articles - BL Direct - All 4 versions

Reduced access to insulin-sensitive tissues in dogs with obesity secondary to increased fat …


M Ellmerer, M Hamilton-Wessler, SP Kim, K … - Diabetes, 2006 - Am Diabetes Assoc
Physiological hyperinsulinemia provokes hemodynamic actions and augments access
of macromolecules to insulin-sensitive tissues. We investigated whether
induction of insulin resistance by a hypercaloric high-fat diet has an ...
Cited by 19 - Related articles - BL Direct - All 5 versions

Direct administration of insulin into skeletal muscle reveals that the transport of insulin …

- diabetesjournals.org
JD Chiu, JM Richey, LN Harrison, E Zuniga, … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Intravenous insulin infusion rapidly increases plasma insulin, yet
glucose disposal occurs at a much slower rate. This delay in insulin's action
may be related to the protracted time for insulin to traverse the capillary ...
Cited by 4 - Related articles - BL Direct - All 5 versions

Physiological hyperinsulinemia has no detectable effect on access of macromolecules to …

- diabetesjournals.org
H Weinhandl, C Pachler, JK Mader, D Ikeoka, … - Diabetes, 2007 - Am Diabetes Assoc
RESULTS—Inulin kinetics in serum were best described using a three-compartment
model incorporating a serum and a fast and a slow equilibrating compartment.
Inulin kinetics in interstitial fluid of peripheral insulin-sensitive ...
Cited by 3 - Related articles - BL Direct - All 4 versions

Decreased muscle capillary permeability surface area in type 2 diabetic subjects

- endojournals.org
S Gudbjornsdottir, M Sjostrand, L Strindberg, … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc
Capillary recruitment in muscles, induced by insulin, has been proposed to be
impaired in insulin-resistant states. To elucidate the mechanisms regulating
capillary transport of insulin and glucose in type 2 diabetes, we directly ...
Cited by 22 - Related articles - All 5 versions

Visceral and truncal subcutaneous adipose tissue are associated with impaired capillary …

- endojournals.org
RT de Jongh, RG Ijzerman, EH Serne, JJ … - Journal of Clinical Endocrinology & Metabolism, 2006 - Endocrine Soc
Context: Central adiposity is associated with cardiovascular risk independently
of total adiposity. Microvascular dysfunction is thought to contribute to
obesity-associated insulin resistance and hypertension and may thus link ...
Cited by 17 - Related articles - BL Direct - All 4 versions

Measurement of interstitial insulin in human adipose and muscle tissue under moderate …

- physiology.org
M Bodenlenz, LA Schaupp, T Druml, R Sommer, … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc
Insulin's action to stimulate glucose utilization is determined by the insulin
concentration in interstitial fluid (ISF) of insulin-sensitive tissues. The
concentration of interstitial insulin has been measured in human ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Mode of Transcapillary Transport of Insulin and Insulin Analog NN304 in Dog Hindlimb


M Hamilton-Wessler, M Ader, MK Dea, D … - Diabetes, 2002 - Am Diabetes Assoc
A defect in transcapillary transport of insulin in skeletal muscle and adipose
tissue has been proposed to play a role in the insulin resistance that leads to
type 2 diabetes, yet the mechanism of insulin transfer across the capillary ...
Cited by 26 - Related articles - BL Direct - All 4 versions

Physiological hyperinsulinaemia increases intramuscular microvascular reactive …


RT De Jongh, ADH Clark, RG IJzerman, EH … - Diabetologia, 2004 - Springer
Aims/hypothesis. Insulin possesses vasodilatory ac- tions that may be important
in regulating its access to insulin-sensitive tissues. Our study aims to
directly measure changes in response to insulin in the human skeletal ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Acute blockade by endothelin-1 of haemodynamic insulin action in rats

- pubget.com [PDF] 
RM Ross, CM Kolka, S Rattigan, MG Clark - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Plasma levels of endothelin-1 are fre- quently elevated
in patients with hypertension, obesity and type 2 diabetes. We hypothesise that
this vasoconstric- tor may prevent full perfusion of muscle, thereby ...
Cited by 10 - Related articles - BL Direct - All 7 versions


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