- ►diabetesjournals.org JL Contreras, C Eckstein, CA Smyth, G Bilbao … - Diabetes, 2004 - Am Diabetes Assoc Clinical studies indicate that significant loss of functional islet mass occurs
in the peritransplant period. Islets are injured as a result of detrimental
effects of brain death, pancreas preservation, islet isolation, hypoxia, ... Cited by 40 - Related articles - BL Direct - All 4 versions
I Thrombosis, IC Death - DIABETES, 2004 - Am Diabetes Assoc Page 1. Activated Protein C Preserves Functional Islet Mass After Intraportal
Transplantation A Novel Link Between Endothelial Cell Activation, ... Related articles
L Ozmen, KN Ekdahl, G Elgue, R Larsson, O … - Diabetes, 2002 - Am Diabetes Assoc A thrombotic/inflammatory reaction is elicited when isolated islets of
Langerhans come in contact with ABO-compatible blood. The detrimental effects of
this instant blood-mediated inflammatory reaction (IBMIR) provide a ... Cited by 94 - Related articles - BL Direct - All 3 versions
H Johansson, M Goto, A Siegbahn, G Elgue, O … - American Journal of Transplantation, 2006 - interscience.wiley.com The instant blood-mediated inflammatory reaction (IBMIR) is triggered in
clinical islet transplantation when human pancreatic islets come in contact with
blood and may explain the initial tissue loss associated with this ... Cited by 29 - Related articles - BL Direct - All 4 versions
NR Barshes, TC Lee, SE Goodpastor, R … - Journal of the American College of Surgeons, 2005 - Elsevier Eleven patients have undergone a total of 26 PITs. An elevated ALT level
occurred in all 11 patients (100%) after the first PIT, with the median post-PIT
peak ALT level reaching 187 IU/L. Transaminitis was less frequent and less ... Cited by 15 - Related articles - All 11 versions
L Moberg, O Korsgren, B Nilsson - Clinical and Experimental Immunology, 2005 - pubmedcentral.nih.gov The poor outcome of intraportal islet transplantation may be explained by the
instant blood-mediated inflammatory reaction (IBMIR), characterized by islet
entrapment in blood clots, leucocyte infiltration and disruption of islet ... Cited by 16 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] W Bennet, B Sundberg, CG Groth, MD Brendel, … - Diabetes, 1999 - Am Diabetes Assoc The remarkable difference in success rates between clinical pancreas
transplantation and islet transplanta- tion is poorly understood. Despite the
same histocom- patibility barrier and similar immunosuppressive treat- ... Cited by 139 - Related articles - BL Direct - All 5 versions
- ►thelancet.com L Moberg, H Johansson, A Lukinius, C Berne, A … - The Lancet, 2002 - Elsevier Intraportal transplantation of pancreatic islets offers improved glycaemic
control and insulin independence in type 1 diabetes mellitus, but intraportal
thrombosis remains a possible complication. The thrombotic reaction may ... Cited by 164 - Related articles - All 9 versions
AM Shapiro, HL Gallant, EG Hao, JRT Lakey, … - Therapeutic drug monitoring, 2005 - journals.lww.com Abstract: Outcomes in clinical islet transplantation improved substantially with
the introduction of combined sirolimus and tacrolimus immunosuppression.
However, multiple islet preparations are often required to achieve insulin ... Cited by 41 - Related articles - All 4 versions
- ►ksu.edu.sa [PDF] P Villiger, EA Ryan, R Owen, K O'Kelly, J … - American Journal of Transplantation, 2005 - ccmjournal.org T he heightened appreciation of the importance of spirituality is reflected in
the growing number of medical schools of- fering courses that either focus on or
include as a topic spirituality in medicine (1). Physicians are being ... Cited by 25 - Related articles - BL Direct - All 9 versions
