KH Yew, KL Prasadan, BL Preuett, MJ Hembree … - Diabetes, 2004 - Am Diabetes Assoc The differentiation of pancreatic exocrine AR42J cells into insulin-expressing
endocrine cells has served as an important model for both endogenous in vivo
β-cell differentiation as well as potential application to β-cell ... Cited by 11 - Related articles - BL Direct - All 4 versions
E Tei, S Mehta, SS Tulachan, H Yew, M … - Pancreas, 2005 - journals.lww.com Objectives: Glucagon-like peptide-1 (GLP-1) is known to stimulate
glucose-dependent insulin production and secretion by pancreatic b-cells.
Preliminary evidence suggests that GLP-1 may also influence endocrine ... Cited by 3 - Related articles - BL Direct - All 3 versions
- ►jbc.org KH Yew, M Hembree, K Prasadan, B Preuett, C … - Journal of Biological Chemistry, 2005 - ASBMB A key goal of cellular engineering is to manipulate progenitor cells to become
-cells, allowing cell replacement therapy to cure diabetes mellitus. As a
paradigm for cell engineering, we have studied the molecular mechanisms by ... Cited by 15 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org P Vazquez, I Roncero, E Blazquez, E Alvarez - Journal of Endocrinology, 2005 - Soc Endocrinology In order to gain better insight into the molecular events involved in the signal
transduction generated through glucagon-like peptide-1 (GLP-1) receptors, we
tested the effect of deletions and point mutations within the cytoplasmic ... Cited by 3 - Related articles - All 2 versions
- ►endocrinology-journals.org P Vazquez, I Roncero, E Blazquez, E Alvarez - Journal of Endocrinology, 2005 - Soc Endocrinology Several G-protein-coupled receptors contain cysteine residues in the C-terminal
tail that may modulate receptor function. In this work we analysed the
substitution of Cys 438 by alanine in the glucagon-like peptide-1 (GLP-1) ... Cited by 6 - Related articles - All 2 versions
JS Dillon, M Lu, S Bowen, LL Homan - Experimental and Clinical Endocrinology and Diabetes, 2005 - thieme-connect.com This study establishes that a single GLP-1 receptor species can mediate the
effects of GLP-1 through multiple signaling pathways, including the adenylyl
cyclase system and intracellular Ca 2+ release, in an ?-cell type. ... Cited by 6 - Related articles - All 4 versions
J Zhou, C Montrose-Rafizadeh, AM Janczewski … - Journal of cellular physiology, 1999 - interscience.wiley.com In this study, AR42J pancreatic acinar cells were used to investigate if
glucagon-like peptide-1 (GLP-1) or glucagon might influence amylase release and
acinar cell function. We first confirmed the presence of GLP-1 receptors on ... Cited by 6 - Related articles - BL Direct - All 3 versions
- ►endocrinology-journals.org MJ Kim, JH Kang, YG Park, GR Ryu, SH Ko, … - Journal of Endocrinology, 2006 - Soc Endocrinology Glucagon-like peptide-1 (GLP-1) and its analog exendin-4 (EX) have been
considered as a growth factor implicated in pancreatic islet mass increase and
ß-cell proliferation. This study aimed to investigate the effect of EX on ... Cited by 19 - Related articles - BL Direct - All 6 versions
- ►nih.gov T Xie, M Chen, QH Zhang, Z Ma, LS Weinstein - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences The G protein α-subunit G s α is required for hormone-stimulated cAMP
generation. In pancreatic β cells, G s α mediates the signaling of
glucagon-like peptide 1 and other incretin hormones, which are implicated ... Cited by 10 - Related articles - BL Direct - All 6 versions
MS Winzell, B Ahrén - Horm Metab Res, 2004 - thieme-connect.com A role for glucagon-like peptide 1 (GLP-1) has been suggested in stimulating
?-cell lipolysis via elevation of cAMP and activation of protein kinase A, which
in turn may activate hormone-sensitive lipase (HSL), thereby contributing ... Cited by 10 - Related articles - All 4 versions
