- ►diabetesjournals.org CS Olofsson, A Salehi, SO Göpel, C Holm, P … - Diabetes, 2004 - Am Diabetes Assoc We have investigated the short-term effects of the saturated free fatty acid
(FFA) palmitate on pancreatic -cells. Palmitate (0.5 or 1 mmol/l bound to fatty
acid–free albumin) stimulated glucagon secretion from intact mouse islets ... Cited by 22 - Related articles - BL Direct - All 4 versions
LC Bollheimer, HC Landauer, S Troll, J … - Metabolism, 2004 - Elsevier While free fatty acids (FFA) are well known as insulin secretagogues, their
effects on pancreatic α cells have been mostly neglected. In the present study
we therefore systematically analyzed the glucagon metabolism of rat ... Cited by 11 - Related articles - All 11 versions
J Hong, R Abudula, J Chen, PB Jeppesen, … - Metabolism, 2005 - Elsevier The influence of fatty acids on beta cell function has been well established
whereas little is known about the role of fatty acids on alpha cell function.
The aim of our study was to investigate the short-term effects of chain ... Cited by 9 - Related articles - All 9 versions
- ►endojournals.org R McGirr, CE Ejbick, DE Carter, JD Andrews, … - Endocrinology, 2005 - Endocrine Soc We have investigated the effects of chronically elevated glucose concentrations
on the pancreatic -cell line TC1-6. We show that basal glucagon secretion and
proglucagon gene expression were increased in response to high glucose ... Cited by 10 - Related articles - BL Direct - All 5 versions
- ►shouxi.net A Salehi, E Vieira, E Gylfe - Diabetes, 2006 - Am Diabetes Assoc Hypersecretion of glucagon contributes to the dysregulation of glucose
homeostasis in diabetes. To clarify the underlying mechanism, glucose-regulated
glucagon secretion was studied in mouse pancreatic islets and clonal ... Cited by 23 - Related articles - BL Direct - All 5 versions
YM Leung, I Ahmed, L Sheu, RG Tsushima, … - Biochemical and Biophysical Research …, 2006 - Elsevier In low or absence of glucose, α-cells generate rhythmic action potentials and
secrete glucagon. α-Cell T-type Ca 2+ channels are believed to be pacemaker
channels, which are expected to open near the resting membrane potential ... Cited by 9 - Related articles - All 5 versions
E Takahashi, M Ito, N Miyamoto, T Nagasu, M … - International journal of molecular medicine, 2005 - cat.inist.fr The voltage-dependent N-type Ca 2 + channel is localized in the
plasma membrane of insulin-releasing β-cells and glucagon-releasing α-cells in
the islets of Langerhans in the pancreas. To examine the contribution of ... Cited by 9 - Related articles - All 5 versions
- ►nih.gov S Vignali, V Leiss, R Karl, F Hofmann, A … - The Journal of Physiology, 2006 - Physiological Soc Insulin and glucagon are the major hormones of the islets of Langerhans that are
stored and released from the B- and A-cells, respectively. Both hormones are
secreted when the intracellular cytosolic Ca 2+ concentration ([Ca 2+ ] i ) ... Cited by 18 - Related articles - BL Direct - All 7 versions
- ►endojournals.org M Fox, E Jocelyn, AV Gyulkhandanyan, LS … - Endocrinology, 2006 - Endocrine Soc In contrast to mouse, rat islet ß-cell membrane potential is reported not to
oscillate in response to elevated glucose despite demonstrated oscillations in
calcium and insulin secretion. We aim to clarify the electrical activity of ... Cited by 10 - Related articles - BL Direct - All 4 versions
A Munoz, M Hu, K Hussain, J Bryan, L … - Endocrinology, 2005 - Endocrine Soc Glucagon is a potent counterregulatory hormone that opposes the action of
insulin in controlling glycemia. The cellular mechanisms by which pancreatic
-cell glucagon secretion occurs in response to hypoglycemia are poorly ... Cited by 20 - Related articles - BL Direct - All 5 versions
