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Scholar Results 1 - 10 of about 101 related to Sattar: Elevated alanine aminotransferase predicts new-onset type 2 diabetes independently.... (0.11 sec) 

Elevated alanine aminotransferase predicts new-onset type 2 diabetes …


N Sattar, O Scherbakova, I Ford, DSJ O'Reilly, A … - Diabetes, 2004 - Am Diabetes Assoc
We examined the association of serum alanine aminotransferase (ALT) with features of the metabolic
syndrome and whether it predicted incident diabetes independently of routinely measured factors
in 5,974 men in the West of Scotland Coronary Prevention Study. A total of 139 men ...
Cited by 111 - Related articles - BL Direct - All 10 versions

Elevations in markers of liver injury and risk of type 2 diabetes


AJG Hanley, K Williams, A Festa, LE Wagenknecht, RB … - Diabetes, 2004 - Am Diabetes Assoc
A limited number of studies have reported associations of markers of liver injury, including elevated
concentrations of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), with
prospective risk of type 2 diabetes. However, only one study has adjusted for a detailed ...
Cited by 107 - Related articles - BL Direct - All 9 versions

High alanine aminotransferase is associated with decreased hepatic insulin …

- diabetesjournals.org
B Vozarova, N Stefan, RS Lindsay, A Saremi, RE … - Diabetes, 2002 - Am Diabetes Assoc
It has been proposed that liver dysfunction may contribute to the development of type 2
diabetes. The aim of the present study was to examine whether elevated hepatic enzymes (alanine
aminotransferase [ALT], aspartate aminotransferase [AST], or γ -glutamyltranspeptidase [ ...
Cited by 199 - Related articles - BL Direct - All 7 versions

Hepatic enzymes, the metabolic syndrome, and the risk of type 2 diabetes in older …


SG Wannamethee, AG Shaper, L Lennon, PH … - Diabetes Care, 2005 - Am Diabetes Assoc
RESULTS—In cross-sectional analyses, alanine aminotransferase (ALT) and γ-glutamyltransferase
(GGT) were strongly associated with obesity, insulin resistance, and the metabolic
syndrome. Prospectively, the risk of type 2 diabetes significantly increased with ...
Cited by 81 - Related articles - BL Direct - All 5 versions

Liver enzymes, the metabolic syndrome, and incident diabetes: the Mexico City …


M Nannipieri, C Gonzales, S Baldi, R Posadas, K … - Diabetes Care, 2005 - 万方数据资源系统
OBJECTIVE: To test the hypothesis that enzymes conventionally associated with liver dysfunction
(aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase [GGT], and
alkaline phosphatase) may predict diabetes. RESEARCH DESIGN AND METHODS ...
Cited by 101 - Related articles - BL Direct - All 4 versions

Serum γ-glutamyltransferase and risk of metabolic syndrome and type 2 diabetes …

- diabetesjournals.org
N Nakanishi, K Suzuki, K Tatara - Diabetes Care, 2004 - Am Diabetes Assoc
RESULTS—With adjustment for age, family history of diabetes, BMI, alcohol intake, cigarette
smoking, regular physical activity (fasting plasma glucose for the risk of type 2 diabetes), and
white blood cell (WBC) count, the risk of metabolic syndrome and type 2 diabetes ...
Cited by 114 - Related articles - BL Direct - All 5 versions

Hepatic markers and development of type 2 diabetes in middle aged men and …


P Andre, B Balkau, C Born, B Royer, E Wilpart, MA … - Diabetes and Metabolism, 2005 - Elsevier
Adjusting on age, only φGT was predictive of diabetes in both sexes, whereas ALT and
aspartate-aminotransferase (AST) were only predictive in men, and bilirubin was not
predictive. After adjustment on classical confounding factors and on ALT activity, the odds ...
Cited by 28 - Related articles - BL Direct - All 3 versions

{gamma}-Glutamyltransferase, obesity, and the risk of type 2 diabetes: …

- endojournals.org
DH Lee, K Silventoinen, DR Jacobs Jr, P … - Journal of Clinical …, 2004 - Endocrine Soc
Serum -glutamyltransferase (GGT) concentration within its normal range has emerged as an
important predictor in the pathogenesis of diabetes. We studied serum GGT as a predictor of
type 2 diabetes incidence and a possible interaction between obesity and GGT on the ...
Cited by 69 - Related articles - BL Direct - All 7 versions

Liver markers and development of the metabolic syndrome

- diabetesjournals.org
AJG Hanley, K Williams, A Festa, LE Wagenknecht, RB … - Diabetes, 2005 - Am Diabetes Assoc
Nonalcoholic fatty liver disease (NAFLD) is emerging as a component of the metabolic
syndrome, although it is not known whether markers of NAFLD, including elevated concentrations
of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline ...
Cited by 117 - Related articles - BL Direct - All 6 versions

Alanine aminotransferase predicts coronary heart disease events: a 10-year follow- …


RK Schindhelm, JM Dekker, G Nijpels, LM Bouter, CDA … - Atherosclerosis, 2007 - Elsevier
Alanine aminotransferase (ALT) is a marker of non-alcoholic fatty liver disease (NAFLD) and
predicts incident type 2 diabetes mellitus (DM2). Recently, ALT was shown to be also associated
with endothelial dysfunction and carotid atherosclerosis. We studied the predictive value ...
Cited by 88 - Related articles - All 18 versions


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