- ►diabetesjournals.org KM Utzschneider, DB Carr, RL Hull, K Kodama, JB … - Diabetes, 2004 - Am Diabetes Assoc The prevalence of glucose intolerance and type 2 diabetes increases with age. To determine
whether the hyperbolic relationship between insulin sensitivity and the insulin response is affected
by age and whether the decline in β-cell function with age is related to increases in intra- ... Cited by 35 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org R Basu, E Breda, AL Oberg, CC Powell, C Dalla Man, A … - Diabetes, 2003 - Am Diabetes Assoc Glucose tolerance decreases with age. For determining the cause of this decrease, 67 elderly
and 21 young (70.1 ± 0.7 vs. 23.7 ± 0.8 years) participants ingested a mixed meal and received
an intravenous injection of glucose. Fasting glucose and the glycemic response above ... Cited by 121 - Related articles - BL Direct - All 5 versions
- ►endojournals.org B Ahren, G Pacini - Journal of Clinical Endocrinology & Metabolism, 1998 - Endocrine Soc This study examined whether insulin secretion, insulin sensitivity, glucose effectiveness (S G
), and hepatic extraction (HE) of insulin are altered by age when glucose tolerance is
normal. A frequently sampled iv glucose tolerance test was performed in 20 elderly (E, ... Cited by 32 - Related articles - BL Direct - All 4 versions
R Basu, C Dalla Man, M Campioni, A Basu, G Klee, G … - Diabetes, 2006 - Am Diabetes Assoc To determine the effects of age and sex on the regulation of postprandial glucose
metabolism, glucose turnover, insulin secretion, insulin action, and hepatic insulin extraction
were concurrently measured in 145 healthy elderly (aged 70 ± 1 years) and in 58 young ( ... Cited by 38 - Related articles - BL Direct - All 4 versions
- ►endojournals.org KM Utzschneider, DB Carr, SM Barsness, SE … - Journal of Clinical …, 2004 - Endocrine Soc Although weight loss in older subjects has been shown to improve insulin sensitivity, it is unclear
what effect this lifestyle intervention has on ß-cell function. To determine whether diet-induced
weight loss can improve ß-cell function in older subjects, we studied 19 healthy male ... Cited by 34 - Related articles - BL Direct - All 4 versions
A Gastaldelli, AM Sironi, D Ciociaro, V Positano, E … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 2090–2096 DOI 10.1007/s00125-005-1891-3 ARTICLE A.
Gastaldelli . AM Sironi . D. Ciociaro . V. Positano . E. Buzzigoli . D. Giannessi . M. Lombardi . A.
Mari . E. Ferrannini Visceral fat and beta cell function in non-diabetic humans ... Cited by 15 - Related articles - BL Direct - All 3 versions
C Della Man, A Caumo, C Cobelli - IEEE Transactions on …, 2002 - ieeexplore.ieee.org Abstract Recently, a new approach has been proposed to estimate insulin sensitivity (S/sub
I/) from an oral glucose tolerance test or a meal using an "integral equation". Here, we improve
on the "integral equation" by resorting to a "differential equation" approach. The classic ... Cited by 51 - Related articles - All 4 versions
- ►physiology.org CD Man, A Caumo, R Basu, R Rizza, G … - American Journal of …, 2005 - Am Physiological Soc The oral glucose minimal model (OMM) measures insulin sensitivity (S I ) and the glucose rate
of appearance (R a ) of ingested glucose in the presence of physiological changes of insulin
and glucose concentrations. However, S I of OMM measures the overall effect of insulin ... Cited by 20 - Related articles - BL Direct - All 4 versions
G Toffolo, F De Grandi, C Cobelli - Diabetes, 1995 - Am Diabetes Assoc Parametric models of insulin secretion are used to measure indexes of beta-cell function from
plasma C-peptide concentration during an intravenous glucose tolerance test (IVGTT). Since
the models have been usually assessed against plasma C-peptide data, both secretory ... Cited by 57 - Related articles - BL Direct - All 4 versions
[CITATION] Intensive blood-glucose control with sulphonylureas or insulin compared with …