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Scholar Results 1 - 10 of about 101 related to de Jongh: Free fatty acid levels modulate microvascular function. (0.13 sec) 

Free fatty acid levels modulate microvascular function


RT de Jongh, EH Serné, RG IJzerman, G de … - Diabetes, 2004 - Am Diabetes Assoc
To test the hypothesis that free fatty acids (FFAs) modulate microvascular
function and that this contributes to obesity-associated insulin resistance,
hypertension, and microangiopathy, we examined the effects of both FFA ...
Cited by 71 - Related articles - BL Direct - All 4 versions

Lipid infusion impairs physiologic insulin-mediated capillary recruitment and muscle glucose …


LH Clerk, S Rattigan, MG Clark - Diabetes, 2002 - Am Diabetes Assoc
Infusion of triglycerides and heparin causes insulin resistance in muscle.
Because the vascular actions of insulin, particularly capillary recruitment, may
contribute to the increase in glucose uptake by skeletal muscle, we ...
Cited by 76 - Related articles - BL Direct - All 5 versions

Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle

- shouxi.net
LH Clerk, MA Vincent, LA Jahn, Z Liu, JR … - Diabetes, 2006 - Am Diabetes Assoc
We have previously shown that skeletal muscle capillaries are rapidly recruited
by physiological doses of insulin in both humans and animals. This facilitates
glucose and insulin delivery to muscle, thus augmenting glucose uptake. In ...
Cited by 55 - Related articles - BL Direct - All 5 versions

Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose …


MA Vincent, LH Clerk, JR Lindner, AL Klibanov … - Diabetes, 2004 - Am Diabetes Assoc
Insulin increases glucose disposal into muscle. In addition, in vivo insulin
elicits distinct nitric oxide synthase-dependent vascular responses to increase
total skeletal muscle blood flow and to recruit muscle capillaries (by ...
Cited by 99 - Related articles - BL Direct - All 5 versions

Physiological concentrations of insulin induce endothelin-dependent vasoconstriction of …

- ahajournals.org
EC Eringa, CDA Stehouwer, K Walburg, AD … - Arteriosclerosis, thrombosis, and vascular biology, 2006 - Am Heart Assoc
Methods and Results— Insulin-mediated vasoreactivity of isolated resistance
arteries of the rat cremaster muscle to insulin (4 to 3400 µU/mL) was studied
in the absence and presence of TNF- (10 ng/mL). Although insulin or TNF- ...
Cited by 29 - Related articles - All 9 versions

Impaired microvascular function in obesity: implications for obesity-associated …

- ahajournals.org
RT de Jongh, EH Serne, RG IJzerman, G de … - Circulation, 2004 - Am Heart Assoc
From the Department of Medicine (RTJ, EHS, RGIJ, GV, CDAS), VU University
Medical Center, Amsterdam, Netherlands, and Institute for Cardiovascular
Research, Vrije Universiteit (RTJ, EHS, RGIJ, CDAS), Amsterdam, Netherlands.
Cited by 95 - Related articles - BL Direct - All 5 versions

Physiologic hyperinsulinemia enhances human skeletal muscle perfusion by capillary …

- diabetesjournals.org
M Coggins, J Lindner, S Rattigan, L Jahn, E … - Diabetes, 2001 - Am Diabetes Assoc
Despite intensive study, the relation between insulin's action on blood flow and
glucose metabolism remains unclear. Insulin-induced changes in microvascular
perfusion, independent from effects on total blood flow, could be an ...
Cited by 96 - Related articles - BL Direct - All 5 versions

TNF-α levels are associated with skin capillary recruitment in humans: a potential …


R Ijzerman, J Voordouw, M VanWeissenbruch … - Clinical Science, 2006 - submit.clinsci.org
Key words: body mass index, capillary recruitment, microcirculation, insulin
resistance, tumour necrosis factor (TNF). ... Abbreviations: BMI, body mass
index; CI, confidence interval; CV, coefficient of variation; IQR, ...
Cited by 15 - Related articles - Cached - BL Direct - All 8 versions

Physiological hyperinsulinaemia increases intramuscular microvascular reactive …


RT De Jongh, ADH Clark, RG IJzerman, EH … - Diabetologia, 2004 - Springer
Aims/hypothesis. Insulin possesses vasodilatory ac- tions that may be important
in regulating its access to insulin-sensitive tissues. Our study aims to
directly measure changes in response to insulin in the human skeletal ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Impaired Microvascular Function in Obesity


I Resistance - Circulation - Am Heart Assoc
Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams &
Wilkins, a division of Wolters ... Implications for Obesity-Associated ...
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