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Scholar Results 1 - 10 of about 101 related to Lewis: Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resis.... (0.12 sec) 

Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the …


GF Lewis, S Murdoch, K Uffelman, M Naples, L Szeto, … - Diabetes, 2004 - Am Diabetes Assoc
Postheparin plasma hepatic lipase (HL) activity has been shown to correlate with features of
the metabolic syndrome and type 2 diabetes in humans. We examined HL postheparin plasma
enzyme activity, hepatocyte mRNA, and protein mass in the insulin-resistant, fructose-fed ...
Cited by 27 - Related articles - BL Direct - All 4 versions

Triglyceride enrichment of HDL does not alter HDL-selective cholesteryl ester …

- jlr.org
S Rashid, KD Uffelman, PHR Barrett, P Vicini, K … - The Journal of Lipid …, 2001 - ASBMB
Triglyceride (TG) enrichment of high density lipoprotein (HDL), which occurs in hypertriglyceridemic
states, significantly enhances the rate at which HDL apolipoprotein (apo)AI is cleared from the
circulation of healthy humans. In the New Zealand White (NZW) rabbit, a species naturally ...
Cited by 18 - Related articles - BL Direct - All 4 versions

Expression of human hepatic lipase in the rabbit model preferentially enhances the …

- ahajournals.org
S Rashid, DK Trinh, KD Uffelman, JS Cohn, DJ Rader, … - Circulation, 2003 - Am Heart Assoc
Background— We have shown previously that triglyceride (TG) enrichment of HDL, as occurs
in hypertriglyceridemic states, contributes to HDL lowering in humans by enhancing the clearance
of HDL apolipoprotein (apo) AI from the circulation. In the New Zealand White rabbit, an ...
Cited by 28 - Related articles - All 6 versions

Clearance of postprandial and lipolytically modified human HDL in rabbits and rats

- jlr.org [PDF] 
GF Lewis, B Lamarche, KD Uffelman, AC … - The Journal of Lipid …, 1997 - ASBMB
Department of Medicine, Division of Endocrinology,* University of Toronto, Toronto, Ontario,
Canada M5G 2C4, and The Resource Facility for Kinetic Analysis: Center for
Bioengineering, Box 352255, University of Washington, Seattle, WA 98195-2255
Cited by 30 - Related articles - BL Direct - All 3 versions

Scavenger receptor class B type I in high-density lipoprotein metabolism, …


B Trigatti, S Covey, A Rizvi - Biochemical Society Transactions, 2004 - bst.portlandpress.com
The scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that can mediate the
binding and bi-directional lipid transfer between high-density lipoproteins (HDLs) and cells. It
is expressed in a variety of tissues, including the liver, and in macrophages in ...
Cited by 24 - Related articles - Cached - BL Direct - All 10 versions

Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the …

- ahajournals.org
S Rashid, PHR Barrett, KD Uffelman, T … - … , and vascular biology, 2002 - Am Heart Assoc
The precise biochemical mechanisms underlying the reduction of HDL levels in hypertriglyceridemic
states are currently not known. In humans, we showed that triglyceride (TG) enrichment of
HDL, as occurs in hypertriglyceridemic states, enhances the clearance of HDL-associated ...
Cited by 57 - Related articles - BL Direct - All 7 versions

Remnant high density lipoprotein2 particles produced by hepatic lipase display …


K Guendouzi, X Collet, B Perret, H Chap, R Barbaras - Biochemistry, 1998 - ncbi.nlm.nih.gov
We had previously shown that hepatic lipase plays a prominent role in promoting the generation
of pre-beta HDL particles from triglyceride rich HDL2, leaving an alpha-HDL particle of decreased
size that was named "remnant HDL2" [Barrans, A., et al. (1994) J. Biol. Chem. 269, 11572- ...
Cited by 21 - Related articles - BL Direct - All 4 versions

Biochemical and Physical Properties of Remnant-HDL2 and of Pre [beta] 1-HDL …


K Guendouzi, B Jaspard, R Barbaras, C Motta, C Vieu, … - Biochemistry, 1999 - pubs.acs.org
The hepatic lipase acting on triglyceride-rich high-density lipoprotein 2 (HDL 2 ) induces the
formation of preβ 1 -HDL, leaving a residual alpha-migrating HDL particle that was named
“remnant-HDL 2 ” (Barrans, A., Collet, X., Barbaras, R., Jaspard, B., Manent, J., Vieu, C., ...
Cited by 22 - Related articles - BL Direct - All 5 versions

Thematic review series: Patient-Oriented Research. What have we learned about …

- jlr.org
S Rashid, BW Patterson, GF Lewis - The Journal of Lipid Research, 2006 - ASBMB
Plasma measurements of lipids, lipoproteins, and apolipoproteins provide information on the
static levels of these fractions without providing key information on the dynamic fluxes of lipoproteins
in the circulation. Kinetics studies, in contrast, provide additional information on the ...
Cited by 14 - Related articles - BL Direct - All 6 versions

Reverse cholesterol transport is regulated by varying fatty acyl chain saturation and …

- nih.gov
P Marmillot, S Patel, MR Lakshman - Metabolism, 2007 - Elsevier
Because phospholipid composition of high-density lipoprotein (HDL) plays a vital role in its reverse
cholesterol transport (RCT) function, we studied RCT in vitro (uptake and efflux) with reconstituted
HDLs (rHDLs) containing phosphatidylcholine (PC) with fatty acids of increasing ...
Cited by 4 - Related articles - All 9 versions


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