V Thallas-Bonke, C Lindschau, B Rizkalla, LA … - Diabetes, 2004 - Am Diabetes Assoc This study investigated the role of advanced glycation end products (AGEs) in
mediating protein kinase C (PKC) isoform expression in diabetic nephropathy. In
vitro, vascular smooth muscle cells incubated in a high-glucose (25-mmol/l) ... Cited by 67 - Related articles - BL Direct - All 5 versions
- ►fasebj.org [PDF] JM Forbes, V Thallas, MC Thomas, HW … - The FASEB Journal, 2003 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.02-1102fje. Published online
July 18, 2003. The breakdown of pre-existing advanced glycation end ... Cited by 127 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org J Menne, JK Park, M Boehne, M Elger, C … - Diabetes, 2004 - Am Diabetes Assoc Activation of protein kinase C (PKC) isoforms has been implicated in the
pathogenesis of diabetic nephropathy. We showed earlier that PKC-α is activated
in the kidneys of hyperglycemic animals. We now used PKC-α −/− mice to ... Cited by 52 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org MC Thomas, C Tikellis, WM Burns, K … - Journal of the American Society of Nephrology, 2005 - Am Soc Nephrol Although hemodynamic and metabolic factors are individually implicated in the
development of diabetic nephropathy, their interaction has not been defined
clearly. In this study, the effects of angiotensin II (Ang II) and advanced ... Cited by 42 - Related articles - BL Direct - All 6 versions
JL Figarola, S Scott, S Loera, C Tessler, P … - Diabetologia, 2003 - Springer Aims/hypothesis. Advanced glycation and lipoxidation endproducts have been
implicated in the pathogenesis of diabetic complications, including diabetic
nephrop- athy. LR-90, a new advanced glycation endproduct in- hibitor, was ... Cited by 54 - Related articles - BL Direct - All 3 versions
JM Forbes, T Soulis, V Thallas, S … - Diabetologia, 2001 - Springer It has been hypothesized that the biochemical pro- cess of advanced glycation
plays an important part in the pathogenesis of diabetic vascular complications
[1] and particularly in diabetic nephropathy [2]. This hypothesis was based ... Cited by 109 - Related articles - BL Direct - All 3 versions
- ►asnjournals.org M Lassila, KK Seah, TJ Allen, V Thallas, … - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol ABSTRACT. Hyperlipidemia not only may be relevant to cardiovascular disease in
diabetes but may also play a role in the development and progression of diabetic
nephropathy. Furthermore, there is increasing evidence that advanced ... Cited by 50 - Related articles - BL Direct - All 7 versions
TM Osicka, Y Yu, S Panagiotopoulos, SP … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc This study examined whether the prevention of dia- betes-related albuminuria by
aminoguanidine (AG) or ramipril (RAM) may be mediated by a common post–
glomerular basement membrane renal intracellular mechanism involving ... Cited by 88 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org JL Wilkinson-Berka, DJ Kelly, SM Koerner, K … - Diabetes, 2002 - Am Diabetes Assoc The severe diabetic nephropathy that develops in the hypertensive transgenic
(mRen-2)27 rat with streptozotocin (STZ) diabetes has previously been considered
angiotensin II-dependent. Because metabolic pathways are also activated in ... Cited by 66 - Related articles - BL Direct - All 6 versions
A Flyvbjerg, L Denner, BF Schrijvers, RG … - Diabetes, 2004 - Am Diabetes Assoc Advanced glycation end products (AGEs) have been implicated in the pathogenesis
of diabetic kidney disease. The actions of AGEs are mediated both through a
non–receptor-mediated pathway and through specific receptors for AGE ... Cited by 68 - Related articles - BL Direct - All 4 versions
