- ►diabetesjournals.org S Chen, Y Kasama, JS Lee, B Jim, M Marin, … - Diabetes, 2004 - Am Diabetes Assoc Podocyte-derived vascular endothelial growth factor (VEGF) is upregulated in
diabetes and may contribute to albuminuria. Although believed to act upon the
glomerular endothelium, VEGF may have pronounced effects on the podocyte ... Cited by 51 - Related articles - BL Direct - All 4 versions
MC Iglesias-de la Cruz, FN Ziyadeh, M Isono … - Kidney international, 2002 - nature.com The podocyte takes center stage in the pathogenesis of glomerular basement
membrane (GBM) thickening and proteinuria in diabetic glomerulopathy. In part,
GBM thickening may occur when the podocyte synthesizes increased amounts of ... Cited by 121 - Related articles - BL Direct - All 7 versions
HC Chen, CA Chen, JY Guh, JM Chang, SJ … - Life sciences, 2000 - Elsevier The adhesion molecule integrin α3β1 is the major receptor of podocyte to the
glomerular capillary basement membrane (GBM). Since progressive alteration of
the glomerular extracellular matrix (ECM) compartment leading to GBM ... Cited by 69 - Related articles - BL Direct - All 4 versions
H Kakizawa, Y Itoh, S Imamura, T Matsumoto, … - Hormone and Metabolic Research, 2004 - thieme-connect.com Two endothelium-derived factors, endothelin (ET), a vasoconstrictor, and
vascular endothelial growth factor (VEGF), an angiogenic factor are thought to
be involved in the pathogenesis of diabetic vascular complications. The aim ... Cited by 17 - Related articles - BL Direct - All 5 versions
A Pätäri, C Forsblom, M Havana, H Taipale, … - Diabetes, 2003 - Am Diabetes Assoc Diabetic nephropathy is the leading cause of end-stage renal disease. Because
early diagnosis and treatment may prevent the complication, new tools for an
early detection are needed. One of the key components of the glomerular ... Cited by 50 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org A Flyvbjerg, F Dagnæs-Hansen, AS De Vriese, … - Diabetes, 2002 - Am Diabetes Assoc Diabetic nephropathy in type 2 diabetic patients is a frequent complication
associated with increased morbidity and mortality. Various growth factors and
cytokines have been implicated in the pathogenesis of diabetic kidney ... Cited by 180 - Related articles - BL Direct - All 4 versions
- ►oxfordjournals.org S Chen, JS Lee, MC Iglesias-De La Cruz, A … - Nephrology Dialysis Transplantation, 2005 - ERA-EDTA Results. AngII 10 –10 M was found to stimulate the production of 3(IV)
collagen significantly in as short a time as 3 h. The expression of 3(IV)
collagen was influenced by the TGF-ß system, but AngII did not increase ... Cited by 43 - Related articles - All 5 versions
- ►diabetesjournals.org S Doublier, G Salvidio, E Lupia, V … - Diabetes, 2003 - Am Diabetes Assoc We studied the distribution of nephrin in renal biopsies from 17 patients with
diabetes and nephrotic syndrome (7 type 1 and 10 type 2 diabetes), 6 patients
with diabetes and microalbuminuria (1 type 1 and 5 type 2 diabetes), and 10 ... Cited by 163 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org M Dalla Vestra, A Masiero, AM Roiter, A Saller … - Diabetes, 2003 - Am Diabetes Assoc Podocyte structural changes have been suggested to be involved in the
pathogenesis of albuminuria in diabetes. We evaluated podocytes density, number,
and structure in 67 white patients with type 2 diabetes: 21 ... Cited by 125 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org PT Brinkkoetter, S Holtgrefe, FJ van der … - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol The permselectivity of the GBM is partly due to the high negative charge of HSPG
and their interaction with other matrix components (8–10). Most studies on the
decrease of glomerular HSPG in patients with DN have suggested that a ... Cited by 24 - Related articles - BL Direct - All 8 versions
