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Scholar Results 1 - 10 of about 101 related to Weedon: Common variants of the hepatocyte nuclear factor-4α P2 promoter are associated with.... (0.14 sec) 

Common variants of the hepatocyte nuclear factor-4α P2 promoter are associated with type …

- diabetesjournals.org
MN Weedon, KR Owen, B Shields, G Hitman, M … - Diabetes, 2004 - Am Diabetes Assoc
Hepatocyte nuclear factor (HNF)-4α is part of a transcription factor network
that is key for the development and function of the β-cell. Rare mutations in
the HNF4α gene cause maturity-onset diabetes of the young. A number of ...
Cited by 85 - Related articles - BL Direct - All 5 versions

Association testing of variants in the hepatocyte nuclear factor 4α gene with risk of type 2 …

- diabetesjournals.org
W Winckler, RR Graham, PIW de Bakker, M Sun … - Diabetes, 2005 - Am Diabetes Assoc
Two recent publications reported association of common polymorphisms in the P2
promoter of hepatocyte nuclear factor 4α (HNF4α) (the MODY1 gene) with risk
for type 2 diabetes. We attempted to reproduce this putative association by ...
Cited by 59 - Related articles - All 8 versions

A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor- …

- diabetesjournals.org
LD Love-Gregory, J Wasson, J Ma, CH Jin, B … - Diabetes, 2004 - Am Diabetes Assoc
Variants in hepatocyte nuclear factor-4α (HNF4α), a transcription factor that
influences the expression of glucose metabolic genes, have been correlated with
maturity-onset diabetes of the young, a monogenic form of diabetes. ...
Cited by 168 - Related articles - BL Direct - All 6 versions

Genetic variation near the hepatocyte nuclear factor-4α gene predicts susceptibility to type 2 …

- umich.edu [PDF] 
K Silander, KL Mohlke, LJ Scott, EC Peck, P … - Diabetes, 2004 - Am Diabetes Assoc
The Finland-United States Investigation Of NIDDM Genetics (FUSION) study aims to
identify genetic variants that predispose to type 2 diabetes by studying
affected sibling pair families from Finland. Chromosome 20 showed our ...
Cited by 204 - Related articles - BL Direct - All 10 versions

Polymorphisms in both promoters of hepatocyte nuclear factor 4-α are associated with type …

- diabetesjournals.org
CM Damcott, N Hoppman, SH Ott, LJ Reinhart, J … - Diabetes, 2004 - Am Diabetes Assoc
Hepatocyte nuclear factor 4-α (HNF4A) is a transcription factor located on
chromosome 20q13 that regulates expression of genes involved in glucose
metabolism and homeostasis. Recently, two groups independently identified ...
Cited by 54 - Related articles - BL Direct - All 6 versions

Variation near the hepatocyte nuclear factor (HNF)-4α gene associates with type 2 diabetes …


SK Hansen, CS Rose, C Glümer, T Drivsholm, … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 452–458 DOI 10.1007/s00125-005-1671-0 ARTICLE SK
Hansen . CS Rose . C. Glümer . T. Drivsholm . K. Borch-Johnsen . ...
Cited by 42 - Related articles - All 5 versions

Effect of common polymorphisms in the HNF4α promoter on susceptibility to type 2 diabetes …


M Vaxillaire, C Dina, S Lobbens, A Dechaume … - Diabetologia, 2005 - Springer
Page 1. Diabetologia (2005) 48: 440–444 DOI 10.1007/s00125-004-1665-3 SHORT
COMMUNICATION M. Vaxillaire . C. Dina . S. Lobbens . A. Dechaume . ...
Cited by 27 - Related articles - All 3 versions

Variants in hepatocyte nuclear factor 4α are modestly associated with type 2 diabetes in …

- diabetesjournals.org
YL Muller, AM Infante, RL Hanson, L Love- … - Diabetes, 2005 - Am Diabetes Assoc
Single nucleotide polymorphisms (SNPs) within the hepatocyte nuclear factor 4α
(HNF4α) gene are associated with type 2 diabetes in Finns and Ashkenazi Jews.
Previous studies in both populations have reported linkage to type 2 ...
Cited by 37 - Related articles - BL Direct - All 6 versions

A large-scale association analysis of common variation of the HNF1α gene with type 2 …

- shouxi.net
MN Weedon, KR Owen, B Shields, G Hitman, M … - Diabetes, 2005 - Am Diabetes Assoc
HNF1α (TCF1) is a key transcription factor that is essential for pancreatic
β-cell development and function. Rare mutations of HNF1α cause maturity-onset
diabetes of the young. A common variant, G319S, private to the Oji-Cree ...
Cited by 38 - Related articles - BL Direct - All 7 versions

Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes

- shouxi.net
AM Bagwell, JL Bento, JC Mychaleckyj, BI … - Diabetes, 2005 - Am Diabetes Assoc
Hepatocyte nuclear factor 4α (HNF4A), the gene for the maturity-onset diabetes
of the young type 1 monogenic form of type 2 diabetes, is within the type 2
diabetes–linked region on chromosome 20q12-q13.1 and, consequently, is a ...
Cited by 32 - Related articles - All 5 versions


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