ND Palmer, JL Bento, JC Mychaleckyj, CD … - DIABETES-NEW YORK-, 2004 - Am Diabetes Assoc Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 gene, catalyzes the
dephosphorylation of pro- teins at tyrosyl residues. PTP-1B has been implicated
in negatively regulating insulin signaling by dephosphory- lating the ... Cited by 45 - Related articles - BL Direct - All 6 versions
- ►pubget.com [PDF] JL Bento, ND Palmer, JC Mychaleckyj, LA … - Diabetes, 2004 - Am Diabetes Assoc The PTPN1 gene codes for protein tyrosine phosphatase 1B (PTP1B) (EC 3.1.3.48),
which negatively regulates insulin signaling by dephosphorylating the
phosphotyrosine residues of the insulin receptor kinase activation segment. ... Cited by 69 - Related articles - BL Direct - All 6 versions
- ►shouxi.net JC Florez, CM Agapakis, NP Burtt, M Sun, P … - Diabetes, 2005 - Am Diabetes Assoc Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 gene, inactivates
the insulin signal transduction cascade by dephosphorylating phosphotyrosine
residues in insulin signaling molecules. Due to its chromosomal location ... Cited by 25 - Related articles - All 8 versions
NJ Spencer-Jones, X Wang, H Snieder, TD … - Diabetes, 2005 - Am Diabetes Assoc Protein tyrosine phosphatase-1B negatively regulates leptin and insulin
signaling, potentially contributing to hormonal resistance. We selected six
tagging single nucleotide polymorphisms (SNPs) representing 18 common ... Cited by 18 - Related articles - BL Direct - All 4 versions
SM Echwald, H Bach, H Vestergaard, B … - Diabetes, 2002 - Am Diabetes Assoc In the present study, we tested the hypothesis that variability in the protein
tyrosine phosphatase-1B (PTP-1B) gene is associated with type 2 diabetes. Using
single-strand conformational polymorphism analysis, we examined cDNA of ... Cited by 70 - Related articles - BL Direct - All 4 versions
I Dahlman, H Wahrenberg, L Persson, P Arner - Journal of internal medicine, 2004 - cat.inist.fr No association of reported functional protein tyrosine phosphatase 1 B 3' UTR gene
polymorphism with features of the metabolic syndrome in a Swedish population. ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►endojournals.org A Mok, H Cao, B Zinman, AJG Hanley, SB … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Several lines of evidence support a role for protein tyrosine phosphatase 1B
(PTP-1B) in metabolism, and specifically in insulin sensitivity and obesity. We
report the development of reagents for the amplification and sequencing of ... Cited by 63 - Related articles - BL Direct - All 6 versions
M Santaniemi, O Ukkola, Y A. Kesaniemi - Journal of internal medicine, 2004 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 20 - Related articles - BL Direct - All 4 versions
- ►nih.gov R Di Paola, L Frittitta, G Miscio, M Bozzali, R … - The American Journal of Human Genetics, 2002 - Elsevier Protein tyrosine phosphatase 1B (PTP1B) inhibits insulin signaling and, when
overexpressed, plays a role in insulin resistance (Ahmad et al. 1997). We
identified, in the 3′ untranslated region of the PTP1B gene, a 1484insG ... Cited by 103 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] J Weng, J Yan, Z Huang, Y Sui, L Xiu - Diabetes care, 2003 - Am Diabetes Assoc Type 2 diabetes is both a phenotypi- cally and geneotypically heteroge- neous
disease. It is caused by defective insulin secretion and action. Protein
tyrosine phosphatases (PTPases) play important roles in insulin cascade ... Cited by 9 - Related articles - BL Direct - All 5 versions
