- ►universit%c3%a4t-l%c3%bcbeck.de [PDF] M Hallschmid, C Benedict, B Schultes, HL … - Diabetes, 2004 - Am Diabetes Assoc Insulin acts in the central nervous system to reduce food intake and body weight
and is considered a major adiposity signal. After intranasal administration,
insulin enters the cerebrospinal fluid compartment and alters brain ... Cited by 59 - Related articles - BL Direct - All 10 versions
C Benedict, M Hallschmid, A Hatke, B … - Psychoneuroendocrinology, 2004 - Elsevier Previous studies have suggested an acutely improving effect of insulin on memory
function. To study changes in memory associated with a prolonged increase in
brain insulin activity in humans, here we used the intranasal route of ... Cited by 92 - Related articles - All 7 versions
W Kern, A Peters, B Fruehwald-Schultes, E … - Neuroendocrinology, 2000 - content.karger.com Insulin receptors have been identified in limbic brain structures, but their
functional relevance is still unclear. In order to characterize some of their
effects, we evaluated auditory evoked brain potentials (AEP) in a vigilance ... Cited by 99 - Related articles - BL Direct - All 5 versions
C Benedict, C Dodt, M Hallschmid, M Lepiorz … - Metabolism, 2005 - Elsevier Intranasal administration of insulin has been shown to influence neuroendocrine
functions via an effect on central nervous mechanisms. Because insulin, in
particular when infused into cerebral arteries, induces blood pressure (BP) ... Cited by 8 - Related articles - All 13 versions
DJ Clegg, CA Riedy, KAB Smith, SC Benoit, … - Diabetes, 2003 - Am Diabetes Assoc The distribution of fat in the body differs between the male and female sexes
and is associated with the relative secretion of the two “adiposity”
hormones leptin and insulin. We now report that the brains of male and ... Cited by 82 - Related articles - BL Direct - All 5 versions
- ►nih.gov O Tschritter, H Preissl, AM Hennige, M … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences Animal studies have shown that the brain is an insulin-responsive organ and that
central nervous insulin resistance induces obesity and disturbances in glucose
metabolism. In humans, insulin effects in the brain are poorly ... Cited by 23 - Related articles - BL Direct - All 9 versions
W Kern, C Benedict, B Schultes, F Plohr, A … - Diabetologia, 2006 - Springer To the Editor: In healthy men, insulin concentrations in cerebrospinal fluid
(CSF) increase after acute elevations of plasma insulin levels, indicating that
the brain content of insulin is normally finely tuned to circulating ... Cited by 13 - Related articles - All 4 versions
- ►diabetesjournals.org [PDF] W Kern, J Born, H Schreiber, HL Fehm - Diabetes, 1999 - Am Diabetes Assoc Insulin receptors have been detected in several struc- tures of the brain, yet
the biological significance of insulin acting on the brain remains rather
unclear. In humans, direct central nervous effects of insulin are dif- ... Cited by 88 - Related articles - BL Direct - All 5 versions
K Gerozissis - Cellular and Molecular Neurobiology, 2003 - Springer SUMMARY 1. While many questions remain unanswered, it is now well documented
that, contrary to earlier views, insulin is an important neuromodulator,
contributing to neurobiological processes, in particular energy homeostasis ... Cited by 77 - Related articles - BL Direct - All 6 versions
- ►jneurosci.org SC Benoit, EL Air, LM Coolen, R Strauss, A … - Journal of Neuroscience, 2002 - Soc Neuroscience Like leptin, the pancreatic hormone insulin is an important adiposity signal to
the brain. We report that the hypothalamic melanocortin system is an important
target of the actions of insulin to regulate food intake and body weight. ... Cited by 142 - Related articles - BL Direct - All 8 versions