- ►diabetesjournals.org W Qiu, RK Avramoglu, N Dubé, TM Chong, M … - Diabetes, 2004 - Am Diabetes Assoc Protein tyrosine phosphatase-1B (PTP-1B) plays an important role in regulation
of insulin signal transduction, and modulation of PTP-1B expression seems to
have a profound effect on insulin sensitivity and diet-induced weight gain. ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►pubget.com [PDF] K Overexpression, RNA Studies - DIABETES, 2004 - Am Diabetes Assoc Protein tyrosine phosphatase-1B (PTP-1B) plays an im- portant role in regulation
of insulin signal transduction, and modulation of PTP-1B expression seems to
have a profound effect on insulin sensitivity and diet-induced weight gain. ... Related articles - All 3 versions
CM Rondinone, J Clampit, RJ Gum, BA Zinker, … - Biochemical and Biophysical Research …, 2004 - Elsevier Protein tyrosine phosphatase 1B (PTP1B) inhibition increases insulin sensitivity
and normalizes blood glucose levels in animals. The molecular events associated
with PTP1B inhibition that increase insulin sensitivity remain ... Cited by 5 - Related articles - All 4 versions
JE Clampit, JL Meuth, HT Smith, RM Reilly, … - Biochemical and Biophysical Research …, 2003 - Elsevier Protein-tyrosine phosphatase-1B (PTP1B) has been implicated as a negative
regulator of insulin signaling. PTP1B dephosphorylates the insulin receptor and
insulin receptor substrates (IRS-1/2), inhibiting the insulin-signaling ... Cited by 30 - Related articles - BL Direct - All 4 versions
T Issad, N Boute, S Boubekeur, D Lacasa - Biochimie, 2005 - Elsevier PTP1B is a protein tyrosine-phosphatase predominantly located on the cystosolic
surface of the endoplasmic reticulum. This tyrosine-phosphatase plays a major
role in the regulation of the activity of the insulin receptor (IR). We ... Cited by 18 - Related articles - All 3 versions
- ►leptipro.org [PDF] JA Kushner, FG Haj, LD Klaman, MA Dow, BB … - Diabetes, 2004 - Am Diabetes Assoc Protein tyrosine phosphatase-1b (Ptp1b) inhibits insulin and leptin signaling by
dephosphorylating specific tyrosine residues in their activated receptor
complexes. Insulin signals are mediated by tyrosine phosphorylation of the ... Cited by 29 - Related articles - BL Direct - All 16 versions
W Qiu, R Kohen-Avramoglu, F Rashid-Kolvear, … - Biochemistry, 2004 - pubs.acs.org This work was supported by an operating grant (T-4301) from the Heart and Stroke
Foundation of Ontario to KARK-A. is a recipient of a Heart and Stroke Scientific
Research Corporation of Canada postdoctoral fellowship. CSA is a recipient ... Cited by 24 - Related articles - BL Direct - All 5 versions
- ►jlr.org C Taghibiglou, D Rudy, SC Van Iderstine, A … - The Journal of Lipid Research, 2000 - ASBMB We studied the biogenesis of apolipoprotein B (apoB) in primary hepatocytes
isolated from hamster liver, an animal model with striking resemblance to humans
in lipoprotein metabolism. Hamster hepatocytes were found to assemble and ... Cited by 45 - Related articles - BL Direct - All 4 versions
FG Haj, JM Zabolotny, YB Kim, BB Kahn, BG … - Journal of Biological Chemistry, 2005 - ASBMB Protein-tyrosine phosphatase 1B (PTP1B) is an important negative regulator of
insulin and leptin signaling in vivo. Mice lacking PTP1B (PTP1B–/– mice) are
hyper-responsive to insulin and leptin and resistant to diet-induced ... Cited by 37 - Related articles - All 9 versions
I Gouni-Berthold, E Giannakidou, D Muller- … - Journal of internal medicine, 2005 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 8 - Related articles - All 4 versions
