Y Fujinaka, D Sipula, A Garcia-Ocaña, RC … - Diabetes, 2004 - Am Diabetes Assoc Transgenic overexpression of either parathyroid hormone-related peptide (PTHrP)
or mouse placental lactogen type 1 (mPL1) in pancreatic β-cells, using the rat
insulin II promoter (RIP), results in islet hyperplasia either through ... Cited by 28 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org [PDF] ML Villanueva-Penacarrillo, J Cancelas, F de … - Journal of Endocrinology, 1999 - Soc Endocrinology Parathyroid hormone (PTH)-related protein (PTHrP) is present in the pancreatic
islet. Recent data in transgenic mice suggest that PTHrP might modulate islet
mass and insulin secretion. In the present study, we assessed the effect of ... Cited by 16 - Related articles - All 6 versions
- ►diabetesjournals.org J Roccisana, V Reddy, RC Vasavada, JA … - Diabetes, 2005 - Am Diabetes Assoc Overexpression of hepatocyte growth factor (HGF) in the ß-cell of transgenic
mice enhances ß-cell proliferation, survival, and function. In the current
studies, we have used conditional ablation of the c-met gene to uncover the ... Cited by 33 - Related articles - All 6 versions
[CITATION] Induction of-cell proliferation and retinoblastoma protein phosphorylation in rat and human …
- ►jbc.org RC Vasavada, A Garcia-Ocana, WS Zawalich, … - Journal of Biological Chemistry, 2000 - ASBMB The factors that regulate pancreatic beta cell proliferation are not well
defined. In order to explore the role of murine placental lactogen (PL)-I
(mPL-I) in islet mass regulation in vivo, we developed transgenic mice in ... Cited by 87 - Related articles - BL Direct - All 4 versions
X Zhang, JP Gaspard, Y Mizukami, J Li, F … - Diabetes, 2005 - Am Diabetes Assoc Cyclin D1 can stimulate proliferation by driving cells from the G1 into the
S-phase of the mammalian cell cycle. Previous animal studies have implicated the
G1-S transition as a key regulatory checkpoint governing the proliferation ... Cited by 32 - Related articles - All 5 versions
[CITATION] Loss of expression of cdk4 causes insulin-deficient diabetes and cdk4 activation results in …
A García-Ocaña, RC Vasavada, A Cebrian, V … - Diabetes, 2001 - Am Diabetes Assoc Recent advances in human islet transplantation have highlighted the need for
expanding the pool of ß-cells available for transplantation. We have developed
three transgenic models in which growth factors (hepatocyte growth factor ... Cited by 80 - Related articles - BL Direct - All 4 versions
