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Scholar Results 1 - 10 of about 101 related to Dezaki: Endogenous Ghrelin in Pancreatic Islets Restricts Insulin Release by Attenuating.... (0.14 sec) 

Endogenous Ghrelin in Pancreatic Islets Restricts Insulin Release by Attenuating Ca2+ …


K Dezaki, H Hosoda, M Kakei, S Hashiguchi, … - Diabetes, 2004 - Am Diabetes Assoc
Ghrelin, isolated from the human and rat stomach, is the endogenous ligand for
the growth hormone (GH) secretagogue receptor, which is expressed in a variety
of tissues, including the pancreatic islets. It has been shown that low ...
Cited by 88 - Related articles - BL Direct - All 4 versions

Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits …

- jhc.org
N Wierup, S Yang, RJ McEvilly, H Mulder, F … - Journal of Histochemistry and Cytochemistry, 2004 - Histochemical Soc
GHRELIN is a 28-amino-acid octanoylated peptide isolated from rat stomach as a
ligand of the growth hormone (GH) secretagogue receptor (GHS-R) (Kojima et al.
1999 Go ). Ghrelin is mainly produced by a population of endocrine cells, ...
Cited by 85 - Related articles - BL Direct - All 4 versions

Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice


Y Sun, M Asnicar, PK Saha, L Chan, RG … - Cell metabolism, 2006 - Elsevier
Ghrelin and leptin are suggested to regulate energy homeostasis as mutual
antagonists on hypothalamic neurons that regulate feeding behavior. We employed
reverse genetics to investigate the interplay between ghrelin and leptin. ...
Cited by 70 - Related articles - All 11 versions

Blockade of Pancreatic Islet–Derived Ghrelin Enhances Insulin Secretion to Prevent High- …

- diabetesjournals.org
K Dezaki, H Sone, M Koizumi, M Nakata, M … - Diabetes, 2006 - Am Diabetes Assoc
The gastric hormone ghrelin and its receptor, growth hormone secretagogue
receptor (GHSR), are expressed in pancreas. Here, we report that ghrelin is
released from pancreatic islets to regulate glucose-induced insulin ...
Cited by 41 - Related articles - BL Direct - All 6 versions

Inhibitory effect of ghrelin on insulin and pancreatic somatostatin secretion

- eje-online.org [PDF] 
EM Egido, J Rodriguez-Gallardo, RA Silvestre … - European journal of endocrinology, 2002 - EFES
Objective: Ghrelin is a 28 amino acid residue peptide identified in both human
and rat stomach and which acts as an endogenous ligand for the GH secretagogue
receptor (GHS-R) and stimulates GH release. GHS-Rs are expressed in a ...
Cited by 142 - Related articles - BL Direct - All 10 versions

Dose-dependent inhibition by ghrelin of insulin secretion in the mouse

- endojournals.org
MK Reimer, G Pacini, B Ahren - Endocrinology, 2003 - Endocrine Soc
Ghrelin is produced by stomach oxyntic cells and thought to be involved in the
regulation of body weight and food intake. We demonstrate here that the peptide
inhibits insulin secretion from overnight-incubated mouse islets in the ...
Cited by 132 - Related articles - BL Direct - All 4 versions

Ultrastructure of islet ghrelin cells in the human fetus


N Wierup, F Sundler - Cell and tissue research, 2005 - Springer
Abstract Ghrelin is a peptide hormone predominantly produced in the stomach.
Ghrelin expression has also been reported in other tissues including the
pancreas. We have reported that ghrelin cells constitute a novel endocrine ...
Cited by 28 - Related articles - All 3 versions

Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on the …


M Colombo, S Gregersen, J Xiao, K … - Pancreas, 2003 - journals.lww.com
Page 1. Effects of Ghrelin and Other Neuropeptides (CART, MCH, Orexin A and B,
and GLP-1) on the Release of Insulin From Isolated Rat Islets ...
Cited by 45 - Related articles - BL Direct - All 4 versions

IA-2, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion

- pnas.org
A Doi, T Shono, M Nishi, H Furuta, H Sasaki, … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences
Ghrelin is a newly discovered peptide and an endogenous ligand for growth
hormone (GH) secretagogue (GHS) receptor. It has been shown to possess various
central and peripheral effects, including GH secretion, food intake, and ...
Cited by 17 - Related articles - BL Direct - All 5 versions

Ghrelin cells replace insulin-producing β cells in two mouse models of pancreas …

- nih.gov
CL Prado, AE Pugh-Bernard, L Elghazi, B … - Proceedings of the National Academy of Sciences of …, 2004 - National Acad Sciences
The pancreatic islet is necessary for maintaining glucose homeostasis. Within
the pancreatic islet, the homeodomain protein Nkx2.2 is essential for the
differentiation of all insulin-producing β cells and a subset of glucagon- ...
Cited by 189 - Related articles - BL Direct - All 11 versions


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