SG Straub, G Shanmugam, GWG Sharp - Diabetes, 2004 - Am Diabetes Assoc Electron microscopy and quantitative stereological techniques were used to study the dynamics of the
docked granule pool in the rat pancreatic β-cell. The mean number of granules per β-cell was
11,136. After equilibration in RPMI ... Cited by 23 - Related articles - BL Direct - All 5 versions
R Ivarsson, S Obermuller, GA Rutter, J Galvanovskis, E … - Traffic, 2004 - interscience.wiley.com Glucose-evoked insulin secretion exhibits a biphasic time course and is associated with accelerated
intracellular granule movement. We combined live confocal imaging of EGFP-labelled insulin granules
with capacitance measurements of ... Cited by 17 - Related articles - BL Direct - All 3 versions
- ►biologists.org M Iezzi, G Kouri, M Fukuda, CB Wollheim - Journal of cell science, 2004 - jcs.biologists.org Synaptotagmin (Syt) is involved in Ca 2+ -regulated secretion and has been suggested to serve as a
general Ca 2+ sensor on the membrane of secretory vesicles in neuronal cells. Insulin exocytosis
from the pancreatic ß-cell is an ... Cited by 52 - Related articles - BL Direct - All 5 versions
CS Olofsson, SO Göpel, S Barg, J Galvanovskis, X … - Pflügers Archiv European …, 2002 - Springer Abstract A readily releasable pool (RRP) of granules has been proposed to underlie the first phase
of insulin secretion. In the present study we combined electron mi- croscopy, insulin secretion
measurements and recordings of cell ... Cited by 93 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org T Tsuboi, MA Ravier, LE Parton, GA Rutter - Diabetes, 2006 - Am Diabetes Assoc The mechanism(s) by which chronic hyperglycemia impairs glucose-stimulated insulin secretion is
poorly defined. Here, we compare the "nanomechanics" of single exocytotic events in primary rat
pancreatic ß-cells cultured for 48 ... Cited by 25 - Related articles - BL Direct - All 6 versions
S Speier, M Rupnik - Pflügers Archiv European Journal of Physiology, 2003 - Springer Abstract The tissue-slice technique has enabled major insights into neural and neuroendocrine
physiology. Our aim was to adapt this technique to study the function of the endocrine pancreas. The
preparation combines an in situ ... Cited by 14 - Related articles - BL Direct - All 3 versions
Y Man Leung, L Sheu, E Kwan, G Wang, R … - … and Biophysical Research …, 2002 - Elsevier The examination of insulin exocytosis at the single cell level by conventional electrophysiologic
and amperometric methods possesses inherent limitations, and may not accurately reflect the
morphologic events of exocytosis of ... Cited by 27 - Related articles - BL Direct - All 7 versions
EA Harding, C Kane, RF James, NJ London, … - … medicine and biology, 1997 - ncbi.nlm.nih.gov 1: Adv Exp Med Biol. 1997;426:43-50. Modulation of three types of potassium selective channels
by NAD and other pyridine nucleotides in human pancreatic beta-cells. NAD and K+ channels in
human beta-cells. Harding EA, Kane C, James RF, London NJ, Dunne MJ. ... Cited by 3 - Related articles - BL Direct
A Varadi, T Tsuboi, LI Johnson-Cadwell, VJ Allan, … - … and Biophysical Research …, 2003 - Elsevier Glucose-stimulated mobilization of large dense-core vesicles (LDCVs) to the plasma membrane is
essential for sustained insulin secretion. At present, the cytoskeletal structures and molecular
motors involved in vesicle ... Cited by 29 - Related articles - All 5 versions
- ►biologists.org S Obermuller, A Lindqvist, J Karanauskaite, J … - Journal of Cell …, 2005 - jcs.biologists.org Secretory granules of insulin-secreting cells are used to store and release peptide hormones as well
as low-molecular-weight compounds such as nucleotides. Here we have compared the rate of exocytosis
with the time courses of nucleotide ... Cited by 30 - Related articles - BL Direct - All 4 versions
