- ►diabetesjournals.org SB Catrina, K Okamoto, T Pereira, K Brismar, L … - Diabetes, 2004 - Am Diabetes Assoc Hyperglycemia and hypoxia are suggested to play essential pathophysiological roles in the complications
of diabetes, which may result from a defective response of the tissues to low oxygen tension.
In this study, we show that in primary dermal fibroblasts and endothelial cells, ... Cited by 46 - Related articles - BL Direct - All 4 versions
R Marfella, K Esposito, F Nappo, M Siniscalchi, FC … - Diabetes, 2004 - Am Diabetes Assoc Inadequate angiogenic response to ischemia in diabetic myocardium could result in poor collateral
formation. Because hypoxia-inducible factor (HIF)-1α is a transcriptional activator of vascular
endothelial growth factor (VEGF) and is critical for initiating angiogenic responses to ... Cited by 36 - Related articles - BL Direct - All 5 versions
- ►asnjournals.org P Katavetin, T Miyata, R Inagi, T Tanaka, R … - Journal of the American …, 2006 - Am Soc Nephrol Vascular endothelial growth factor (VEGF) is an important survival factor for endothelial cells
in hypoxic environments. High glucose regulates certain aspects of VEGF expression in various
cell types, including proximal tubular cells. Thus, ambient glucose levels may modulate ... Cited by 28 - Related articles - BL Direct - All 5 versions
L Liu, GP Marti, X Wei, X Zhang, H Zhang, … - Journal of cellular …, 2008 - interscience.wiley.com Wound healing is impaired in elderly patients with diabetes mellitus. We hypothesized that
age-dependent impairment of cutaneous wound healing in db/db diabetic mice: (a) would correlate
with reduced expression of the transcription factor hypoxia-inducible factor 1 (HIF-1 ) as ... Cited by 13 - Related articles - All 2 versions
R Marfella, M D'Amico, C Di Filippo, E Piegari, F Nappo … - Diabetologia, 2002 - Springer Aims/hypothesis. This study aimed to evaluate the ef- fects of hyperglycaemia on the evolution
of myocar- dial infarction and the expression of the transcription- al factor for angiogenesis
hypoxia-inducible factor 1α (HIF-1α) in the rat. Methods. We studied the effects of ... Cited by 62 - Related articles - BL Direct - All 4 versions
K Gradin, C Takasaki, Y Fujii-Kuriyama, K Sogawa - Journal of Biological …, 2002 - ASBMB The hypoxia-inducible factor (HIF)-1α and the HIF-like factor (HLF) transcription factors are regulated
at multiple levels including protein stabilization, nuclear import, and activation of
transactivation, resulting in recruitment of coactivators such as the cAMP-response ... Cited by 53 - Related articles - BL Direct - All 5 versions
K Gradin, C Takasaki, Y Fujii-Kuriyama, K Sogawa - Journal of Biological Chemistry - ASBMB Page 1. The Transcriptional Activation Function of the HIF-like Factor Requires
Phosphorylation at a Conserved Threonine* Katarina Gradin ‡¶ , Chikahisa Takasaki ‡ ,
Yoshiaki Fujii-Kuriyama ঠ, and Kazuhiro Sogawa ठFrom ... Related articles
Q Rich - MEDECINE/SCIENCES, 2002 - disc.vjf.inserm.fr > Les espèces animales ont mis en place un sys- tème ingénieux et conservé d'adaptation rapide
et durable à de fortes baisses de concentration d'oxygène. Le stress hypoxique est " géré " par
la stabilisation et l'activation d'une sous-unité (HIF-1α) du facteur de transcription central, ... Related articles - View as HTML - All 5 versions
WJ Wilson, L Poellinger - Biochemical and Biophysical Research …, 2002 - Elsevier The mechanism of activation of the transcription factor hypoxia-inducible factor-1 (HIF-1) has
been studied extensively. Under normal cellular oxygen conditions protein levels of the alpha
subunit (HIF-1α) are kept low due to massive ubiquitination and subsequent proteosomal ... Cited by 17 - Related articles - BL Direct - All 8 versions
