- ►diabetesjournals.org RA Kowluru, S Odenbach - Diabetes, 2004 - Am Diabetes Assoc Oxidative stress is increased in the retina in diabetes, and it is considered to
play an important role in the development of retinopathy. α-Lipoic acid, a
thiol antioxidant, has been shown to have beneficial effects on ... Cited by 73 - Related articles - BL Direct - All 6 versions
RA Kowluru, P Koppolu, S Chakrabarti, S … - Free radical research, 2003 - informahealthcare.com Oxidative stress is increased in the retina in diabetes, and long-term
administration of antioxidants inhibits the development of retinopathy in
diabetic rats. The purpose of this study is to determine how diabetes ... Cited by 75 - Related articles - BL Direct - All 8 versions
- ►iovs.org RA Kowluru, SN Abbas - Investigative ophthalmology & visual science, 2003 - ARVO METHODS. Mitochondria and cytosol fractions were prepared from retina of rats
with streptozotocin-induced diabetes and from the isolated retinal endothelial
cells and pericytes incubated in 5 or 20 mM glucose medium for up to 10 ... Cited by 52 - Related articles - BL Direct - All 4 versions
RA Kowluru, V Kowluru, Y Xiong, YS Ho - Free Radical Biology and Medicine, 2006 - Elsevier The retina experiences mitochondrial dysfunction in diabetes, superoxide levels
are elevated, and mitochondrial superoxide dismutase (MnSOD) activity is
decreased. Inhibition of superoxide accumulation in diabetes prevents ... Cited by 40 - Related articles - All 5 versions
- ►pubget.com [PDF] J Lin, A Bierhaus, P Bugert, N Dietrich, Y … - Diabetologia, 2006 - Springer Page 1. Diabetologia (2006) 49: 1089–1096 DOI 10.1007/s00125-006-0174-y ARTICLE
J. Lin . A. Bierhaus . P. Bugert . N. Dietrich . Y. Feng . F. vom Hagen . ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►chiroonline.net [PDF] RA Kowluru, J Tang, TS Kern - Diabetes, 2001 - Am Diabetes Assoc Antioxidants were administered to diabetic rats and experimentally galactosemic
rats to evaluate the ability of these agents to inhibit the development of
diabetic retinopathy. Alloxan diabetic rats and nondiabetic rats that were ... Cited by 146 - Related articles - BL Direct - All 6 versions
- ►iovs.org RA Kowluru, L Atasi, YS Ho - Investigative ophthalmology & visual science, 2006 - ARVO PURPOSE. Apoptosis of retinal capillary cells is an early event in the
pathogenesis of retinopathy in diabetes, and oxidative stress has been linked to
accelerated apoptosis of retinal capillary cells. Mitochondria are the ... Cited by 34 - Related articles - BL Direct - All 5 versions
RA Kowluru - Diabetes, 2003 - Am Diabetes Assoc Clinical and experimental studies have shown that reinstitution of good glycemic
control (GC) after a period of poor glycemic control (PC) does not produce
immediate benefits on the progression of retinopathy, and hyperglycemia is ... Cited by 61 - Related articles - BL Direct - All 9 versions
- ►iovs.org TS Kern, J Tang, M Mizutani, RA Kowluru, RH … - Investigative ophthalmology & visual science, 2000 - ARVO METHODS. Rats with alloxan-induced diabetes and rats fed a 30% galactose diet
(known to induce diabetic-like retinopathy) were assigned randomly to receive
diet with (2.5 g/kg diet) or without AMG. After 6 to 8 months of diabetes ... Cited by 126 - Related articles - BL Direct - All 4 versions
- ►iovs.org M Kanwar, PS Chan, TS Kern, RA Kowluru - Investigative ophthalmology & visual science, 2007 - ARVO RESULTS. Retinal mitochondria had twofold increase in superoxide levels in
nontransgenic (wild-type [WT]) diabetic mice compared with WT nondiabetic mice.
In the same retina, diabetes decreased mitochondrial GSH levels by 40% and ... Cited by 33 - Related articles - BL Direct - All 3 versions
