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Scholar Results 1 - 10 of about 101 related to Uehara: Effects of polyol pathway hyperactivity on protein kinase C activity, nociceptive.... (0.09 sec) 

Effects of polyol pathway hyperactivity on protein kinase C activity, nociceptive peptide …


K Uehara, SI Yamagishi, S Otsuki, S Chin, S … - Diabetes, 2004 - Am Diabetes Assoc
We explored the specific impact of polyol pathway hyperactivity on dorsal root
ganglia (DRG) using transgenic mice that overexpress human aldose reductase
because DRG changes are crucial for the development of diabetic sensory ...
Cited by 19 - Related articles - BL Direct - All 4 versions

Differential influence of increased polyol pathway on protein kinase C expressions between …


SI Yamagishi, K Uehara, S Otsuki, S … - Journal of neurochemistry, 2003 - interscience.wiley.com
To explore the relationship between polyol pathway and protein kinase C (PKC),
we examined PKC activities and expressions of PKC isoforms separately in
endoneurial and vessel-rich epineurial tissues in diabetic mice transgenic ...
Cited by 25 - Related articles - BL Direct - All 4 versions

Clinical implications of Nepsilon-(carboxymethyl) lysine, advanced glycation end product, in …


JS Hwang, CH Shin, SW Yang - Diabetes Obesity and Metabolism, 2005 - interscience.wiley.com
Methods: The serum levels of CML were measured in 87 patients with uncomplicated
type 1 diabetes mellitus (12.7 ± 4.6 years of age) and in seven patients with
background retinopathy, microalbuminuria or neuropathy (18.2 ± 5.2 years ...
Cited by 8 - Related articles - All 4 versions

Aldose reductase pathway inhibition improved vascular and C-fiber functions, allowing for …

- shouxi.net
C Demiot, M Tartas, B Fromy, P Abraham, JL … - Diabetes, 2006 - Am Diabetes Assoc
Pressure-induced vasodilation, a neurovascular mechanism relying on the
interaction between mechanosensitive C-fibers and vessels, allows skin blood
flow to increase in response to locally nonnociceptive applied pressure ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Aldose Reductase–Deficient Mice Are Protected From Delayed Motor Nerve Conduction …

- shouxi.net
E Ho, KSL Lam, YS Chen, JCW Yip, M … - Diabetes, 2006 - Am Diabetes Assoc
The exaggerated flux through polyol pathway during diabetes is thought to be a
major cause of lesions in the peripheral nerves. Here, we used aldose reductase
(AR)-deficient (AR −/− ) and AR inhibitor (ARI)-treated mice to further ...
Cited by 30 - Related articles - BL Direct - All 7 versions

The Leptin-Deficient (ob/ob) Mouse

- diabetesjournals.org
VR Drel, N Mashtalir, O Ilnytska, J Shin, F Li … - Diabetes, 2006 - Am Diabetes Assoc
Whereas functional, metabolic, neurotrophic, and morphological abnormalities of
peripheral diabetic neuropathy (PDN) have been extensively explored in
streptozotocin-induced diabetic rats and mice (models of type 1 diabetes), ...
Cited by 31 - Related articles - BL Direct - All 7 versions

[PDF] Effect of treating streptozotocin-induced diabetic rats with sorbinil, myo-inositol or …


LJ Coppey, JS Gellett, EP Davidson, JA … - Experimental Diabesity Research, 2002 - hindawi.com
Page 1. Effect of Treating Streptozotocin-induced Diabetic Rats With Sorbinil,
Myo-inositol or Aminoguanidine on Endoneurial Blood Flow, Motor Nerve Conduction ...
Cited by 24 - Related articles - View as HTML - All 12 versions

[CITATION] Role for 12/15-lipoxygenase in diabetic neuropathy


IG Obrosova, VV Lyzogubov, J Marchand, F … - Diabetes, 2006
Cited by 3 - Related articles

Low-dose poly (ADP-ribose) polymerase inhibitor-containing combination therapies reverse …

- diabetesjournals.org
F Li, VR Drel, C Szabó, MJ Stevens, IG … - Diabetes, 2005 - Am Diabetes Assoc
Poly(ADP-ribose) polymerase (PARP) inhibition has recently been identified as a
novel approach to treatment of experimental peripheral diabetic neuropathy
(PDN). However, long-term inhibition of PARP, an enzyme involved in DNA ...
Cited by 25 - Related articles - All 5 versions

Poly (ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory …

- nih.gov
O Ilnytska, VV Lyzogubov, MJ Stevens, VR … - Diabetes, 2006 - Am Diabetes Assoc
Poly(ADP-ribose) polymerase (PARP) activation is emerging as a fundamental
mechanism in the pathogenesis of diabetes complications including diabetic
neuropathy. This study evaluated the role of PARP in diabetic sensory ...
Cited by 26 - Related articles - BL Direct - All 10 versions


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