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Scholar Results 1 - 10 of about 101 related to Zheng: Development of late-stage diabetic nephropathy in OVE26 diabetic mice. (0.12 sec) 

Development of late-stage diabetic nephropathy in OVE26 diabetic mice


S Zheng, WT Noonan, NS Metreveli, S … - Diabetes, 2004 - Am Diabetes Assoc
OVE26 mice are a transgenic model of severe early-onset type 1 diabetes. These
mice develop diabetes within the first weeks of life and can survive well over a
year with no insulin treatment, and they maintain near normal body weight. ...
Cited by 36 - Related articles - BL Direct - All 5 versions

Ultrastructural and functional analyses of nephropathy in calmodulin-induced diabetic …


EC Carlson, JL Audette, LM Klevay, H Nguyen … - The Anatomical Record, 1997 - interscience.wiley.com
Renal tissues were collected from normal and transgenic mice at 112, 182, and
300 days. These were prepared for light microscopic observation, stained with
polyethylenimine (for anionic sites), or rendered acellular by detergent ...
Cited by 21 - Related articles - BL Direct - All 4 versions

Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic …

- asnjournals.org
HJ Zhao, S Wang, H Cheng, M Zhang, T … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol
Functionally significant polymorphisms in endothelial nitric oxide synthase
(eNOS) and reduced vascular eNOS activity have been associated with increased
human diabetic nephropathy (DN), but the pathogenic role of eNOS deficiency ...
Cited by 41 - Related articles - BL Direct - All 5 versions

Calmodulin-induced early-onset diabetes in transgenic mice.


PN Epstein, PA Overbeek, AR Means - Cell, 1989 - ncbi.nlm.nih.gov
Calmodulin is implicated as the primary transducer of the calcium signal in
pancreatic beta cells, where it is present at very high concentrations. We have
produced three lines of transgenic mice carrying a calmodulin minigene ...
Cited by 97 - Related articles - All 3 versions

Proteomic identification and immunolocalization of increased renal calbindin-D28k …


V Thongboonkerd, S Zheng, KR McLeish, PN … - The Review of Diabetic Studies, 2005 - pubmedcentral.nih.gov
Diabetic nephropathy is a common diabetic complication that is associated with
alterations in the expression of several renal proteins and abnormal calcium
homeostasis. We performed proteomic analysis to screen for global changes ...
Cited by 10 - Related articles - All 5 versions

Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in …


G Proctor, T Jiang, M Iwahashi, Z Wang, J Li, … - Diabetes, 2006 - Am Diabetes Assoc
In Akita and OVE26 mice, two genetic models of type 1 diabetes, diabetic
nephropathy is characterized by mesangial expansion and loss of podocytes,
resulting in glomerulosclerosis and proteinuria, and is associated with ...
Cited by 29 - Related articles - BL Direct - All 5 versions

Alterations in the renal elastin-elastase system in type 1 diabetic nephropathy identified by …

- asnjournals.org
V Thongboonkerd, MT Barati, KR McLeish, C … - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol
ABSTRACT. Diabetes now accounts for >40% of patients with ESRD. Despite
significant progress in understanding diabetic nephropathy, the cellular
mechanisms that lead to diabetes-induced renal damage are incompletely ...
Cited by 83 - Related articles - BL Direct - All 8 versions

Characterization of susceptibility of inbred mouse strains to diabetic nephropathy


Z Qi, H Fujita, J Jin, LS Davis, Y Wang, AB … - Diabetes, 2005 - Am Diabetes Assoc
Differential susceptibility to diabetic nephropathy has been observed in humans,
but it has not been well defined in inbred strains of mice. The present studies
characterized the severity of diabetic nephropathy in six inbred mouse ...
Cited by 45 - Related articles - BL Direct - All 7 versions

Impact of genetic background on nephropathy in diabetic mice

- physiology.org [PDF] 
SB Gurley, SE Clare, KP Snow, A Hu, TW … - American Journal of Physiology- Renal Physiology, 2006 - Am Physiological Soc
44 articles, 25 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/290/1/F214#BIBL ... 17 other
HighWire hosted articles, the first 5 are: This article has been cited by
Cited by 46 - Related articles - BL Direct - All 5 versions

[PDF] Podocyte-specific overexpression of the antioxidant metallothionein reduces diabetic …


S Zheng, EC Carlson, L Yang, PM Kralik, Y … - Journal of the American Society of Nephrology, 2008 - Am Soc Nephrol
ABSTRACT Podocytes are critical components of the selective filtration barrier
of the glomerulus and are susceptible to oxidative damage. For investigation of
the role of oxidative stress and podocyte damage in diabetic nephropathy, ...
Cited by 10 - Related articles - All 5 versions


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