CL Avery, BI Freedman, G Heiss, A Kraja, T Rice, D … - Diabetes, 2004 - Am Diabetes Assoc Type 2 diabetes susceptibility is determined by multiple genetic and environmental factors.
Genome-wide linkage scans have localized common regions, possibly harboring susceptibility
genes on chromosomes 1, 2, 12, and 20. Variability in linkage findings underscores the ... Cited by 20 - Related articles - BL Direct - All 4 versions
P An, BI Freedman, SS Rich, SA Mandel, DK Arnett, RH … - Diabetes, 2006 - Am Diabetes Assoc Genome-wide linkage scans were carried out using a multipoint variance components method
in white and black families of the NHLBI Hypertension Genetic Epidemiology Network
(HyperGEN) study to identify quantitative trait loci (QTLs) for pancreatic β-cell function and ... Cited by 7 - Related articles - BL Direct - All 5 versions
BI Freedman, SS Rich, MM Sale, G Heiss, L Djousse, … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 661–668 DOI 10.1007/s00125-005-1679-5 ARTICLE BI
Freedman . SS Rich . MM Sale . G. Heiss . L. Djoussé . JS Pankow . MA Province . DC Rao .
CE Lewis . YDI Chen . SR Beck . on behalf of the HyperGEN Investigators ... Cited by 13 - Related articles - BL Direct - All 4 versions
YF Chiu, LM Chuang, CF Hsiao, YJ Hung, MW Lin, YT … - Diabetes, 2005 - Am Diabetes Assoc Type 2 diabetes is a complex disease involving both genetic and environmental
components. Abnormalities in insulin secretion and insulin action usually precede the development
of type 2 diabetes and can serve as good quantitative measures for genetic mapping. We ... Cited by 17 - Related articles - All 6 versions
KE North, N Franceschini, IB Borecki, CC Gu, G Heiss, … - Diabetes, 2007 - Am Diabetes Assoc Recent studies have demonstrated the importance of sex effects on the underlying genetic architecture
of insulin-related traits. To explore sex-specific genetic effects on fasting insulin, we tested for
genotype-by-sex interaction and conducted linkage analysis of fasting insulin in ... Cited by 12 - Related articles - BL Direct - All 5 versions
WD Li, C Dong, D Li, C Garrigan, RA Price - Diabetes, 2004 - Am Diabetes Assoc Fasting plasma glucose is a multigenic trait related to both diabetes and obesity. We performed
a genome scan for quantitative fasting plasma glucose levels in 320 families (1,514
subjects), segregating extreme obesity and normal weight using 382 autosomal ... Cited by 12 - Related articles - BL Direct - All 4 versions
TM Frayling, S Wiltshire, GA Hitman, M Walker, JC Levy … - Diabetes, 2003 - Am Diabetes Assoc A young onset of type 2 diabetes is likely to result, in part, from greater genetic susceptibility.
Young-onset families may therefore represent a group in which genes are more easily detectable
by linkage. To test this hypothesis, we conducted age at diagnosis (AAD) stratified linkage ... Cited by 29 - Related articles - BL Direct - All 5 versions
G Jun, Y Song, C Stein, S Iyengar - BMC genetics, 2003 - biomedcentral.com A genome-wide screen was conducted for type 2 diabetes progression genes using measures
of elevated fasting glucose levels as quantitative traits from the offspring enrolled in the Framingham
Heart Study. We analyzed young (20–34 years) and old (≥ 35 years) subjects separately, ... Cited by 6 - Related articles - Cached - All 6 versions
- ►diabetesjournals.org KJ Hunt, DM Lehman, R Arya, S Fowler, RJ Leach, … - Diabetes, 2005 - Am Diabetes Assoc The San Antonio Family Diabetes/Gallbladder Study was initiated to identify susceptibility genes
for type 2 diabetes. Evidence was previously reported of linkage to diabetes on 10q with suggestive
evidence on 3p and 9p in a genome-wide scan of 440 individuals from 27 pedigrees ... Cited by 17 - Related articles - BL Direct - All 5 versions
JY Zhao, MM Xiong, W Huang, H Wang, J Zuo, GD … - Journal of Molecular …, 2005 - Springer J Mol Med (2005) 209:209–215 DOI 10.1007/s00109-004-0587-3 ... JY Zhao · MM Xiong ·
W. Huang · H. Wang · J. Zuo · GD Wu · Z. Chen · BQ Qiang · ML Zhang · JL Chen · W. Ding · WT
Yuan · HY Xu · L. Jin · YX Li · Q. Sun · QY Liu · E. Boerwinkle · FD Fang Cited by 26 - Related articles - All 3 versions
