- ►diabetesjournals.org E Zeggini, J Parkinson, S Halford, KR Owen, … - Diabetes, 2004 - Am Diabetes Assoc The gene encoding insulin receptor substrate-1 (IRS1) represents a strong
biological candidate for a contributory role in type 2 diabetes susceptibility.
Indeed, functional studies have implicated the G971R variant, and a recent ... Cited by 17 - Related articles - BL Direct - All 5 versions
JC Florez, M Sjögren, N Burtt, M Orho- … - Diabetes, 2004 - Am Diabetes Assoc The insulin receptor substrate (IRS)-1 is an important component of the insulin
signal transduction cascade. Several reports suggest that a Gly→Arg change in
codon 972 is associated with type 2 diabetes and related traits, and a ... Cited by 49 - Related articles - BL Direct - All 4 versions
RM Van Dam, B Hoebee, JC Seidell, MM … - Diabetic Medicine, 2004 - interscience.wiley.com Aims The insulin receptor substrate-1 (IRS-1) gene is among the most frequently
studied candidate genes for Type 2 diabetes, but findings have been
inconsistent. This may have been due to generally small study sizes, or to ... Cited by 21 - Related articles - BL Direct - All 4 versions
A Jellema, MPA Zeegers, EJM Feskens, PC … - Diabetologia, 2003 - Springer Aims/hypothesis. Several case-control studies have ex- amined the association
between the Gly972Arg variant in the IRS-1 gene and Type 2 diabetes, but most
had limited power and results could therefore be conflict- ing. Methods. We ... Cited by 75 - Related articles - BL Direct - All 5 versions
[CITATION] Insulin receptor substrate 3 is not essential for growth or glucose metabolism
A Memisoglu, FB Hu, SE Hankinson, S Liu, JB … - Diabetes Care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—The study was a nested case-control study of 387
incident cases of type 2 diabetes and 771 matching control subjects nested
within the Nurses' Health Study, a prospective cohort study. Association ... Cited by 54 - Related articles - BL Direct - All 5 versions
JC Florez, M Sjögren, CM Agapakis, NP Burtt, … - Diabetologia, 2007 - Springer Page 1. ARTICLE Association testing of common variants in the insulin receptor
substrate-1 gene (IRS1) with type 2 diabetes JC Florez ... Cited by 3 - Related articles - BL Direct - All 4 versions
[CITATION] Metabolic syndrome
L Sweeney, AM Brennan, CS Mantzoros - Diabetes and Exercise. Totowa: Humana, 2007 Cited by 3 - Related articles
