- ►diabetesjournals.org CM Damcott, N Hoppman, SH Ott, LJ Reinhart, J Wang, … - Diabetes, 2004 - Am Diabetes Assoc Hepatocyte nuclear factor 4-α (HNF4A) is a transcription factor located on chromosome 20q13
that regulates expression of genes involved in glucose metabolism and homeostasis.
Recently, two groups independently identified single nucleotide polymorphism (SNPs) in ... Cited by 54 - Related articles - BL Direct - All 6 versions
SK Hansen, CS Rose, C Glümer, T Drivsholm, K Borch- … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 452–458 DOI 10.1007/s00125-005-1671-0 ARTICLE SK
Hansen . CS Rose . C. Glümer . T. Drivsholm . K. Borch-Johnsen . T. Jørgensen . O. Pedersen .
T. Hansen Variation near the hepatocyte nuclear factor (HNF)-4α gene ... Cited by 42 - Related articles - All 5 versions
- ►diabetesjournals.org W Winckler, RR Graham, PIW de Bakker, M Sun, P … - Diabetes, 2005 - Am Diabetes Assoc Two recent publications reported association of common polymorphisms in the P2 promoter
of hepatocyte nuclear factor 4α (HNF4α) (the MODY1 gene) with risk for type 2 diabetes. We
attempted to reproduce this putative association by genotyping 11 single nucleotide ... Cited by 59 - Related articles - All 8 versions
AM Bagwell, JL Bento, JC Mychaleckyj, BI Freedman, … - Diabetes, 2005 - Am Diabetes Assoc Hepatocyte nuclear factor 4α (HNF4A), the gene for the maturity-onset diabetes of the young
type 1 monogenic form of type 2 diabetes, is within the type 2 diabetes–linked region on chromosome
20q12-q13.1 and, consequently, is a positional candidate gene for type 2 diabetes in the ... Cited by 32 - Related articles - All 5 versions
- ►diabetesjournals.org K Hara, M Horikoshi, H Kitazato, C Ito, M Noda, J … - Diabetes, 2006 - Am Diabetes Assoc Hepatocyte nuclear factor (HNF)-4α is a transcription factor known as a key molecule in the development
and functions of the β-cells. In a previously performed genome-wide scan of Japanese type 2
diabetic sibpairs, we observed linkage of type 2 diabetes to chromosome 20q12-q13, a ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org MN Weedon, KR Owen, B Shields, G Hitman, M Walker … - Diabetes, 2004 - Am Diabetes Assoc Hepatocyte nuclear factor (HNF)-4α is part of a transcription factor network that is key for the
development and function of the β-cell. Rare mutations in the HNF4α gene cause maturity-onset
diabetes of the young. A number of type 2 diabetes linkage studies have found evidence ... Cited by 85 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org YL Muller, AM Infante, RL Hanson, L Love-Gregory, W … - Diabetes, 2005 - Am Diabetes Assoc Single nucleotide polymorphisms (SNPs) within the hepatocyte nuclear factor 4α (HNF4α) gene
are associated with type 2 diabetes in Finns and Ashkenazi Jews. Previous studies in both populations
have reported linkage to type 2 diabetes near the HNF4α locus on chromosome ... Cited by 37 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org LD Love-Gregory, J Wasson, J Ma, CH Jin, B Glaser, … - Diabetes, 2004 - Am Diabetes Assoc Variants in hepatocyte nuclear factor-4α (HNF4α), a transcription factor that influences the expression
of glucose metabolic genes, have been correlated with maturity-onset diabetes of the young,
a monogenic form of diabetes. Previously, in a genome scan of Ashkenazi Jewish type 2 ... Cited by 169 - Related articles - BL Direct - All 6 versions
K Silander, KL Mohlke, LJ Scott, EC Peck, P Hollstein, … - Diabetes, 2004 - Am Diabetes Assoc The Finland-United States Investigation Of NIDDM Genetics (FUSION) study aims to identify
genetic variants that predispose to type 2 diabetes by studying affected sibling pair families from
Finland. Chromosome 20 showed our strongest initial evidence for linkage. It currently ... Cited by 205 - Related articles - BL Direct - All 10 versions
M Vaxillaire, C Dina, S Lobbens, A Dechaume, V … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 440–444 DOI 10.1007/s00125-004-1665-3 SHORT
COMMUNICATION M. Vaxillaire . C. Dina . S. Lobbens . A. Dechaume . V.
Vasseur-Delannoy . N. Helbecque . G. Charpentier . P. Froguel Effect ... Cited by 27 - Related articles - All 3 versions
