KJ Mitchell, T Tsuboi, GA Rutter - Diabetes, 2004 - Am Diabetes Assoc Changes in intracellular Ca 2+ concentration play a key role in the regulation of insulin secretion
by glucose and other secretagogues. Here, we explore the importance of the secretory pathway
Ca 2+ -ATPase, plasma membrane-related Ca 2+ -ATPase-1 (PMR1; human orthologue ... Cited by 42 - Related articles - BL Direct - All 4 versions
K Van Baelen, J Vanoevelen, G Callewaert, JB … - … and Biophysical Research …, 2003 - Elsevier The secretory-pathway Ca 2+ -ATPase SPCA1 is a thapsigargin-insensitive intracellular Ca
2+ pump found mostly in the Golgi compartment. We have explored the contribution of this Ca
2+ pump to cytosolic Ca 2+ signaling in HeLa cells by using RNA-mediated interference ... Cited by 26 - Related articles - All 6 versions
K VAN BAELEN, J VANOEVELEN, G … - … and biophysical research …, 2003 - cat.inist.fr The secretory-pathway Ca 2 + -ATPase SPCA 1 is a thapsigargin-insensitive intracellular
Ca 2 + pump found mostly in the Golgi compartment. We have explored the contribution
of this Ca 2 + pump to cytosolic Ca 2 + signaling in HeLa cells by using ... Cited by 18 - Related articles
RJ Fairclough, L Dode, J Vanoevelen, JP Andersen … - Journal of Biological …, 2003 - ASBMB ATP2C1, encoding the human secretory pathway Ca 2 + /Mn 2 + ATPase (hSPCA1), was recently
identified as the defective gene in Hailey-Hailey Disease (HHD), an autosomal dominant skin
disorder characterized by persistent blisters and erosions. To investigate the underlying ... Cited by 44 - Related articles - BL Direct - All 5 versions
G Callewaert, JB Parys, H De Smedt, L Raeymaekers, … - Cell Calcium, 2003 - Elsevier Mutations in the ubiquitously expressed secretory-pathway Ca 2+ -ATPase (SPCA1) Ca 2+ pump
result in Hailey–Hailey disease, which almost exclusively affects the epidermal part of the
skin. We have studied Ca 2+ signaling in human keratinocytes by measuring the free Ca ... Cited by 29 - Related articles - All 4 versions
MJ Behne, CL Tu, I Aronchik, E Epstein, G … - Journal of …, 2003 - repositories.cdlib.org Hailey-Hailey disease (MIM16960) is a blistering skin disease caused by mu- tations in the Ca2+
ATPase ATP2C1. We found that the abnormal Ca2+ signaling seen in Hailey-Hailey disease
keratinocytes correlates with decreased protein levels of ATP2C1. Human ATP2C1 ... Cited by 53 - Related articles - BL Direct - All 7 versions
LL Wootton, CCH Argent, M Wheatley, F Michelangeli - BBA-Biomembranes, 2004 - Elsevier Many hormones are known to mediate their action by increasing the level of intracellular Ca
2+ , via either the opening of plasma membrane Ca 2+ channels or by agonist-induced production
of inositol 1,4,5-trisphosphate (IP 3 ) and release of Ca 2+ from intracellular stores via the ... Cited by 23 - Related articles - All 4 versions
J Vanoevelen, L Raeymaekers, JB Parys, H De Smedt, … - Cell Calcium, 2004 - Elsevier Non-mitochondrial intracellular Ca 2+ stores contain both thapsigargin-sensitive
sarco(endo)plasmic-reticulum Ca 2+ -ATPases (SERCA) and thapsigargin-insensitive
secretory-pathway Ca 2+ -ATPases (SPCA1). We now have studied the Ca 2+ -release ... Cited by 27 - Related articles - All 6 versions
M Xiang, D Mohamalawari, R Rao - Journal of Biological Chemistry, 2005 - ASBMB Unlike lower eukaryotes, mammalian genomes have a second gene, ATP2C2, encoding a putative
member of the family of secretory pathway Ca 2+ ,Mn 2+ -ATPases, SPCA2. Human SPCA2
shares 64% amino acid identity with the protein defective in Hailey Hailey disease, ... Cited by 24 - Related articles - All 6 versions
L Missiaen, J Vanoevelen, K Van Acker, L … - … and Biophysical Research …, 2002 - Elsevier We studied the role of the Pmr1-containing Ca 2+ store in COS-1 cells endowed with a functional
endoplasmic reticulum. Transfected cells could be recognized by using a green-fluorescent-protein
(GFP)-tagged form of Pmr1. Pmr1-GFP fluorescence showed a typical juxtanuclear Golgi- ... Cited by 16 - Related articles - BL Direct - All 7 versions
