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Scholar Results 1 - 10 of about 101 related to Sweet: Regulation of ATP/ADP in pancreatic islets. (0.10 sec) 

Regulation of ATP/ADP in pancreatic islets

- diabetesjournals.org
IR Sweet, DL Cook, E DeJulio, AR Wallen, G … - Diabetes, 2004 - Am Diabetes Assoc
ATP and ADP levels are critical regulators of glucose-stimulated insulin
secretion. In many aerobic cell types, the phosphorylation potential (ATP/ADP/P
i ) is controlled by sensing mechanisms inherent in mitochondrial ...
Cited by 37 - Related articles - BL Direct - All 5 versions

Continuous measurement of oxygen consumption by pancreatic islets

- uu.se [PDF] 
IR Sweet, G Khalil, AR Wallen, M Steedman, … - Diabetes Technology & Therapeutics, 2002 - liebertonline.com
IAN R. SWEET, Ph.D., 1 GAMAL KHALIL, Ph.D., 2 ANGELA R. WALLEN, BA, 1 ... MARK
STEEDMAN, BS, 2 KENNETH A. SCHENKMAN, MD, Ph.D., ... JO ANNA REEMS, Ph.D., 4
STEVEN E. KAHN, MB, Ch.B., 1,5 and JAMES B. CALLIS, Ph.D. 2
Cited by 39 - Related articles - BL Direct - All 8 versions

Dynamic perifusion to maintain and assess isolated pancreatic islets


IR Sweet, DL Cook, RW Wiseman, CJ … - Diabetes Technology & Therapeutics, 2002 - liebertonline.com
IAN R. SWEET, Ph.D., 1 DANIEL L. COOK, MD, Ph.D., 2 ROBERT W. WISEMAN, Ph.D.,
3,4 ... CARLA J. GREENBAUM, MD, 6 ÅKE LERNMARK, Ph.D., 1 ... SHINICHI
MATSUMOTO, MD, Ph.D., 5 JEANETTE C. TEAGUE, BS, 1
Cited by 22 - Related articles - BL Direct - All 4 versions

Contribution of calcium influx in mediating glucose-stimulated oxygen consumption in …

- diabetesjournals.org
IR Sweet, M Gilbert - Diabetes, 2006 - Am Diabetes Assoc
In brain, muscle, and pancreatic islets, depolarization induces an increase in
respiration, which is dependent on calcium influx. The goal of this study was to
assess the quantitative significance of this effect in islets relative to ...
Cited by 10 - Related articles - BL Direct - All 6 versions

The role of current product release criteria for identification of human islet preparations …


M Eckhard, D Brandhorst, D Winter, C Jaeger, … - Transplantation proceedings, 2004 - Elsevier
Alloimmunity, autoimmunity, and nonspecific inflammation are known to be
potential determinants for long-term islet survival and insulin independence.
Sufficient islet mass is a key determinant. But islet engraftment and ...
Cited by 13 - Related articles - All 15 versions

Glucose stimulation of cytochrome C reduction and oxygen consumption as assessment of …


IR Sweet, M Gilbert, R Jensen, O Sabek, DW … - Transplantation, 2005 - journals.lww.com
Amajor impediment to the optimization of islet isolation procedures is the lack
of methods that adequately assess the quality of islets (1, 2). An in vitro
method of assessing human islets prior to transplantation could prevent the ...
Cited by 17 - Related articles - All 6 versions

NMR spectroscopy in beta cell engineering and islet transplantation


KK Papas, CK Colton, JS Gounarides, ES … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2001 - interscience.wiley.com
Abstract: Islet transplantation is a promising method for restoring
normoglycemia and alleviating the long term complications of diabetes.
Widespread application of islet transplantation is hindered by the limited ...
Cited by 16 - Related articles - BL Direct - All 3 versions

No correlation between in vitro and in vivo function of human islets


IC Gerling, M Kotb, D Fraga, O Sabek, AO … - Transplantation proceedings, 1998 - Elsevier
The NOD-scid mouse has been shown to support tissue and cellular xenografts
better than the CB17-scid because in addition to the SCID defect, the NOD-scid
have impaired innate immunity.[3] Using NOD-scid mice, we developed a model ...
Cited by 15 - Related articles - BL Direct - All 4 versions

[PDF] Cre recombinase-dependent expression of a constitutively active mutant allele of the …


CM Niswender, BS Willis, A Wallen, IR Sweet … - genesis, 2005 - med.uio.no
Summary: Using the cre-loxP recombination system, we generated a line of mice
expressing a constitutively active catalytic subunit of Protein Kinase A (PKA)
in a temporally and spatially regulated fashion. In the absence of cre ...
Cited by 6 - Related articles - View as HTML - BL Direct - All 5 versions

Human islet oxygen consumption rate and DNA measurements predict diabetes reversal in …


KK Papas, CK Colton, RA Nelson, PR Rozak, … - American Journal of Transplantation, 2007 - interscience.wiley.com
There is a need for simple, quantitative and prospective assays for islet
quality assessment that are predictive of islet transplantation outcome. The
current state-of-the-art athymic nude mouse bioassay is costly, technically ...
Cited by 17 - Related articles - BL Direct - All 4 versions


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