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Scholar Results 1 - 10 of about 101 related to Muzumdar: Decrease in glucose-stimulated insulin secretion with aging is independent of insulin.... (0.09 sec) 

Decrease in glucose-stimulated insulin secretion with aging is independent of insulin action


R Muzumdar, X Ma, G Atzmon, P Vuguin, X … - Diabetes, 2004 - Am Diabetes Assoc
While the incidence of diabetes increases with age, a decrease in β-cell
function independent of age-related insulin resistance has not been conclusively
determined. We studied insulin secretion (by hyperglycemic clamp) in 3-, ...
Cited by 31 - Related articles - BL Direct - All 4 versions

Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion …


KM Ramsey, KF Mills, A Satoh, S Imai - Aging cell, 2008 - pubmedcentral.nih.gov
Cited by 19 - Related articles - BL Direct - All 4 versions

Mechanism of impaired glucose-potentiated insulin secretion in diabetic 90% pancreatectomy …

- nih.gov [PDF] 
YA Hosokawa, H Hosokawa, C Chen, JL … - Journal of Clinical Investigation, 1996 - pubmedcentral.nih.gov
Chronic hyperglycemia causes a near-total disappearance of glucose-induced
insulin secretion. To determine if glu- cose potentiation of nonglucose
secretagogues is impaired, insulin responses to 10 9 M glucagonlike ...
Cited by 32 - Related articles - BL Direct - All 7 versions

Long-term consumption of fermented soybean-derived Chungkookjang enhances …


DY Kwon, JS Jang, SM Hong, JE Lee, SR Sung … - European Journal of Nutrition, 2007 - Springer
DY Kwon Food Functional Research Division Korean Food Research Institutes Seoul,
Korea JS Jang Æ SM Hong Æ JE Lee Æ SR Sung HR Park Æ S. Park, PhD (&) Dept.
of Food and Nutrition Institute of Basic Sciences Hoseo University 165 ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Independent influence of age on basal insulin secretion in nondiabetic humans

- endojournals.org
P Iozzo, H Beck-Nielsen, M Laakso, U Smith, H … - Journal of Clinical Endocrinology & Metabolism, 1999 - Endocrine Soc
Glucose tolerance deteriorates with aging. To test whether age per se impairs
basal ß-cell function, we analyzed retrospective clamp data from a large group
(n = 957) of nondiabetic Europeans over the 18–85 yr age range (the ...
Cited by 82 - Related articles - BL Direct - All 5 versions

Insulin resistance during aging: role for the brain renin-angiotensin system


SD Oden, PE Gallagher, CM Ferrario, D … - Stroke, 2004 - pt.wkhealth.com
Long term systemic blockade of the renin-angiotensin system (RAS) with either an
angiotensin (Ang) II type 1 (AT 1 ) receptor antagonist or angiotensin
converting enzyme inhibitor improves insulin sensitivity and decreases risk ...
Cited by 3 - Related articles

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes


S Imai, W Kiess - Frontiers in bioscience: a journal and virtual library - pubmedcentral.nih.gov
Both genetic and environmental factors contribute to the pathogenesis of type 2
diabetes, and it is critical to understand the interplay between these factors
in the regulation of insulin secretion and insulin sensitivity to develop ...
Cited by 4 - Related articles - All 3 versions

[CITATION] Linear correlation between-cell mass and body weight throughout the lifespan in Lewis rats: …


E Montanya, V Nacher, M Biarnes, J Soler - Diabetes, 2000
Cited by 17 - Related articles

Sirtuins: A universal link between NAD, metabolism, and aging


S Imai, L Guarente - The molecular biology of aging, 2007 - books.google.com
Sirtuins: A Universal Link between NAD, Metabolism, and Aging Shin-ichiro Imai
Department of Molecular Biology and Pharmacology Washington University School of
Medicine St. Louis, Missouri 63110 Leonard P. Guarente Department of ...
Cited by 6 - Related articles - BL Direct - All 3 versions

Mechanisms of the age-associated deterioration in glucose tolerance

- diabetesjournals.org
R Basu, E Breda, AL Oberg, CC Powell, C … - Diabetes, 2003 - Am Diabetes Assoc
Glucose tolerance decreases with age. For determining the cause of this
decrease, 67 elderly and 21 young (70.1 ± 0.7 vs. 23.7 ± 0.8 years)
participants ingested a mixed meal and received an intravenous injection of ...
Cited by 120 - Related articles - BL Direct - All 5 versions


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