KR Bidasee, Y Zhang, CH Shao, M Wang, KP … - Diabetes, 2004 - Am Diabetes Assoc Prolongation of relaxation is a hallmark of diabetic cardiomyopathy. Most
studies attribute this defect to decreases in sarco(endo)plasmic reticulum Ca 2+
-ATPase (SERCA2a) expression and SERCA2a-to-phospholamban (PLB) ratio. ... Cited by 59 - Related articles - BL Direct - All 4 versions
KR Bidasee, K Nallani, Y Yu, RR Cocklin, Y … - Diabetes, 2003 - Am Diabetes Assoc Decrease in cardiac contractility is a hallmark of chronic diabetes. Previously
we showed that this defect results, at least in part, from a dysfunction of the
type 2 ryanodine receptor calcium-release channel (RyR2). The mechanism(s) ... Cited by 43 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org DD Belke, EA Swanson, WH Dillmann - Diabetes, 2004 - Am Diabetes Assoc Although it is known that insulin-dependent (type 1) diabetes results in
depressed contractile performance associated with diminished sarcoendoplasmic
reticular Ca 2+ -ATPase (SERCA2a) activity, findings in insulin-resistant ... Cited by 53 - Related articles - BL Direct - All 6 versions
- ►fasebj.org [PDF] R Vetter, U Rehfeld, C Reissfelder, W Weiss … - The FASEB Journal, 2002 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.01-1019fje. Published online
August 21, 2002. Transgenic overexpression of the sarcoplasmic reticulum Ca 2+ ... Cited by 45 - Related articles - BL Direct - All 6 versions
SU Trost, DD Belke, WF Bluhm, M Meyer, E … - Diabetes, 2002 - Am Diabetes Assoc Diabetic cardiomyopathy is characterized by reduced cardiac contractility due to
direct changes in heart muscle function independent of vascular disease. An
important contributor to contractile dysfunction in the diabetic state is ... Cited by 112 - Related articles - BL Direct - All 5 versions
- ►physiology.org KR Bidasee, H Zheng, CH Shao, SK Parbhu, … - Journal of Applied Physiology, 2008 - Am Physiological Soc The present study was undertaken to assess cardiac function and characterize
β-adrenoceptor subtypes in hearts of diabetic rats that underwent exercise
training (ExT) after the onset of diabetes. Type 1 diabetes was induced in ... Cited by 5 - Related articles - All 5 versions
Z Vasanji, NS Dhalla, T Netticadan - Molecular and cellular biochemistry, 2004 - Springer The sarcoplasmic reticulum (SR) plays a critical role in mediating cardiac
contractility and its function is abnormal in the diabetic heart. However, the
mechanisms underlying SR dysfunction in the diabetic heart are not clear. ... Cited by 9 - Related articles - BL Direct - All 4 versions
ND Evcimen, BD Pekiner, S Nebioglu - Diabetes & metabolism, 1999 - ncbi.nlm.nih.gov Kidney Ca(2+)-ATPase activity was altered in streptozotocin (STZ)-induced
diabetic rats. Male rats, 200-250 g, were rendered diabetic by injection of STZ
45 mg/kg body weight via the tail vein. Following injection, control rats ... Cited by 10 - Related articles - BL Direct - All 2 versions
- ►physiology.org J Suarez, DD Belke, B Gloss, T Dieterle, PM … - American Journal of Physiology- Heart and Circulatory …, 2004 - Am Physiological Soc In many types of heart failure cardiac myocyte Ca 2+ handling is abnormal
because of downregulation of key Ca 2+ -handling proteins like
sarco(endo)plasmic reticulum Ca 2+ -ATPase (SERCA)2a and ryanodine receptor ... Cited by 45 - Related articles - BL Direct - All 4 versions
